The Challenge of Radiation-Induced Restrictive Cardiomyopathy and Outcomes After Heart Transplantation

2016 ◽  
Vol 22 (6) ◽  
pp. 479-480 ◽  
Author(s):  
Guy A. MacGowan
Keyword(s):  
Heart Transplantation ◽  
Restrictive Cardiomyopathy ◽  
Radiation Induced

Restrictive Cardiomyopathy and Risk of Mortality on Waiting List for Heart Transplantation

2014 ◽  
Vol 33 (4) ◽  
pp. S66-S67 ◽  
Author(s):  
E.M. Hsich ◽  
R.C. Starling ◽  
E. Blackstone ◽  
J. Rogers ◽  
D.O. Taylor ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Restrictive Cardiomyopathy ◽  
Waiting List ◽  
Risk Of Mortality

scholarly journals Idiopathic endomyocardial fibrosis in a Western European: a case report

2020 ◽  
Vol 4 (3) ◽  
pp. 1-5
Author(s):  
Guillaume Théry ◽  
Laurent Faroux ◽  
Philippe Deleuze ◽  
Damien Metz
Keyword(s):  
Heart Failure ◽  
Heart Transplantation ◽  
Restrictive Cardiomyopathy ◽  
Functional Class ◽  
First Episode ◽  
Endomyocardial Fibrosis ◽  
Optimal Management ◽  
Poor Outcomes ◽  
End Stage

Abstract Background Endomyocardial fibrosis (EMF) is a rare cause of restrictive cardiomyopathy, mainly found in tropical/subtropical country. Endomyocardial fibrosis causes severe congestive symptoms and may lead to end-stage heart failure. Case summary A French Caucasian 44-year-old man without noticeable medical history and who had never travelled outside of France was hospitalized for a first episode of acute heart failure revealing an atypical appearance of the left ventricle. Cardiac magnetic resonance (CMR) identified EMF, but investigations did not identify any aetiology (no eosinophilia). Despite optimal management of chronic heart failure, functional class declined rapidly resulting in several hospitalizations for heart failure. The patient finally underwent an elective heart transplantation with good results at 6-month follow-up. Discussion Endomyocardial fibrosis exact physiopathology remains unclear, although association with eosinophilia has been reported. Diagnosis is challenging and is based on multi-modal imagery with a central role of CMR. There is no consensus on optimal management, medical therapy having poor outcomes and rate of peri-operative complications being high. Heart transplantation should be considered for eligible patients.

Pediatric Heart Transplantation for Congenital and Restrictive Cardiomyopathy

2013 ◽  
Vol 95 (5) ◽  
pp. 1675-1684 ◽  
Author(s):  
Bari Murtuza ◽  
Matthew Fenton ◽  
Michael Burch ◽  
Arun Gupta ◽  
Nagarajan Muthialu ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Restrictive Cardiomyopathy ◽  
Pediatric Heart Transplantation

Use of oral budesonide in the management of protein-losing enteropathy due to restrictive cardiomyopathy

2013 ◽  
Vol 24 (4) ◽  
pp. 764-766 ◽  
Author(s):  
Hazım A. Gursu ◽  
Birgul Varan ◽  
Ilkay Erdogan
Keyword(s):  
Heart Failure ◽  
Serum Albumin ◽  
Heart Transplantation ◽  
Male Patient ◽  
Cardiac Transplantation ◽  
Serum Albumin Level ◽  
Restrictive Cardiomyopathy ◽  
Albumin Level ◽  
Protein Losing Enteropathy ◽  
Eyelid Oedema

AbstractA 7-year-old male patient who had abdominal swelling and eyelid oedema was diagnosed with restrictive cardiomyopathy. His serum albumin level was 2.3 g/dl. Protein-losing enteropathy due to restrictive cardiomyopathy was diagnosed and oral budesonide was started. His serum albumin level began to rise and ascites and peripheric oedema disappeared. The patient underwent a successful cardiac transplantation and budesonide was stopped. After the heart transplantation, the albumin level decreased to 2.3 g/dl, and therefore it was restarted. When the serum albumin level increased, the budesonide dose was tapered and stopped in 1 month. Budesonide may be an effective drug in patients with protein-losing enteropathy due to heart failure.

scholarly journals Coronary pathology in patients after chest radiotherapy

2021 ◽  
Vol 27 (2) ◽  
pp. 78-83
Author(s):  
Denislav Biserov ◽  
Mariana Konteva ◽  
Ivaneta Yoncheva ◽  
Svetoslav Gogov
Keyword(s):  
Radiation Therapy ◽  
Clinical Picture ◽  
Clinical Symptoms ◽  
Acute Myocarditis ◽  
Restrictive Cardiomyopathy ◽  
Heart Damage ◽  
The Past ◽  
Oncological Patients ◽  
Radiation Induced ◽  
Artery Disease

Radiation therapy is the main treatment for a large number of neoplastic diseases. Improved survival in this group of patients led to the emergence of a new nosological unit – radiation-induced damage to neighbouring organs and systems. Data accumulated in recent decades has proven conclusively that chest radiotherapy could result in heart damage. Cardiovascular diseases are the leading cause of death in oncological patients in remission. The onset of radiation-induced heart disease (RIHD) can be early with clinical picture of acute myocarditis and late with manifestations of constrictive pericarditis, restrictive cardiomyopathy, coronary artery disease, valvular involvement, heart failure and conduction pathology. Clinical symptoms may manifest years after exposure to radiation. Our team performed a mini-review on the topic, after which we shared our own experience in 10 patients who underwent radiation therapy in the past and were admitted to the Clinic of Cardiology of University Multyprofile Hospital for Active Treatment „Deva Mariya“ with a clinical picture of ACS.

scholarly journals Successful Heart Transplantation Following Decompressive Craniectomy in a Patient with Restrictive Cardiomyopathy and Extensive Stroke in the Region of the Right Middle Cerebral Artery

2014 ◽  
Vol 2 (3) ◽  
pp. 474-478
Author(s):  
Salih Gulsen
Keyword(s):  
Heart Transplantation ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Decompressive Craniectomy ◽  
Antithrombotic Therapy ◽  
Heart Diseases ◽  
Restrictive Cardiomyopathy ◽  
Embolic Stroke ◽  
The Right ◽  
Patients Experience

Restrictive cardiomyopathy (RCM) in children is associated with a greater risk of embolic stroke than are other congenital heart diseases. After diagnosis, 50% of children with RCM die within 2 years without heart transplantation. As such, all RCM patients are placed on the heart transplantation list and must wait for an appropriate heart for transplantation. Every type of embolic stroke can occur while waiting for a donor heart; therefore, the cardiovascular team must initiate antithrombotic therapy at time RCM is diagnosed. Some pediatric RCM patients experience embolic stroke (50% are the cerebral type) despite antithrombotic therapy, including acetylsalicylic acid, warfarin, and heparine. Neurosurgeons working in hospitals that perform organ transplantation expect to see RCM cases with restrictive large cerebral infarct. We think that decompressive craniectomy should be performed as soon as possible after determining the clinical condition of any patient with RCM and a large right middle cerebral artery (MCA) infarct.

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