Right Ventricular Longitudinal Strain Correlates Well With Right Ventricular Stroke Work Index in Patients With Advanced Heart Failure Referred for Heart Transplantation

2012 ◽  
Vol 18 (3) ◽  
pp. 208-215 ◽  
Author(s):  
Matteo Cameli ◽  
Matteo Lisi ◽  
Francesca Maria Righini ◽  
Charilaos Tsioulpas ◽  
Sonia Bernazzali ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Transplantation ◽  
Right Ventricular ◽  
Longitudinal Strain ◽  
Advanced Heart Failure ◽  
Stroke Work ◽  
Work Index ◽  
Stroke Work Index ◽  
Ventricular Stroke Work Index ◽  
Right Ventricular Stroke Work

scholarly journals High Right Ventricular Stroke Work Index Is Associated with Worse Kidney Function in Patients with Heart Failure with Preserved Ejection Fraction

2018 ◽  
Vol 8 (2) ◽  
pp. 123-129 ◽  
Author(s):  
Napatt Kanjanahattakij ◽  
Natee Sirinvaravong ◽  
Francisco Aguilar ◽  
Akanksha Agrawal ◽  
Parasuram Krishnamoorthy ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Right Ventricular ◽  
Linear Regression Analysis ◽  
Stroke Work ◽  
Work Index ◽  
Patients With Heart Failure ◽  
Stroke Work Index ◽  
Ventricular Stroke Work Index ◽  
Right Ventricular Stroke Work

Background: In patients with heart failure with preserved ejection fraction (HFpEF), worse kidney function is associated with worse overall cardiac mechanics. Right ventricular stroke work index (RVSWI) is a parameter of right ventricular function. The aim of our study was to determine the relationship between RVSWI and glomerular filtration rate (GFR) in patients with HFpEF. Method: This was a single-center cross-sectional study. HFpEF is defined as patients with documented heart failure with ejection fraction > 50% and pulmonary wedge pressure > 15 mm Hg from right heart catheterization. RVSWI (normal value 8–12 g/m/beat/m2) was calculated using the formula: RVSWI = 0.0136 × stroke volume index × (mean pulmonary artery pressure – mean right atrial pressure). Univariate and multivariate linear regression analysis was performed to study the correlation between RVSWI and GFR. Result: Ninety-one patients were included in the study. The patients were predominantly female (n = 64, 70%) and African American (n = 61, 67%). Mean age was 66 ± 12 years. Mean GFR was 59 ± 35 mL/min/1.73 m2. Mean RVSWI was 11 ± 6 g/m/beat/m2. Linear regression analysis showed that there was a significant independent inverse relationship between RVSWI and GFR (unstandardized coefficient = –1.3, p = 0.029). In the subgroup with combined post and precapillary pulmonary hypertension (Cpc-PH) the association remained significant (unstandardized coefficient = –1.74, 95% CI –3.37 to –0.11, p = 0.04). Conclusion: High right ventricular workload indicated by high RVSWI is associated with worse renal function in patients with Cpc-PH. Further prospective studies are needed to better understand this association.

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