scholarly journals Elevated Cystatin C Predicts Long-Term Adverse Cardiac Events in Patients with Heart Failure Independent of Natriuretic Peptide Levels and Creatinine Clearance

2011 ◽  
Vol 17 (8) ◽  
pp. S23
Author(s):  
Matthias Dupont ◽  
Earl B. Britt ◽  
Yuping Wu ◽  
Stanley L. Hazen ◽  
Wilson W.H. Tang
Keyword(s):  
Heart Failure ◽  
Creatinine Clearance ◽  
Natriuretic Peptide ◽  
Cystatin C ◽  
Cardiac Events ◽  
Adverse Cardiac Events ◽  
Patients With Heart Failure

scholarly journals Liver Stiffness for Predicting Adverse Cardiac Events in Chinese Patients With Heart Failure: A Two-year Prospective Study

2021 ◽  
Author(s):  
Qian Wang ◽  
Yuqing Song ◽  
Qiming Wu ◽  
Qian Dong ◽  
Song Yang
Keyword(s):  
Heart Failure ◽  
Platelet Count ◽  
Natriuretic Peptide ◽  
Liver Stiffness ◽  
Chinese Patients ◽  
Cardiac Events ◽  
Natriuretic Peptide Level ◽  
Adverse Cardiac Events ◽  
Patients With Heart Failure

Abstract Background. To investigate whether liver stiffness (LS) can predict adverse cardiac events in Chinese patients with heart failure (HF). Methods. Total of 53 hospitalized patients with HF were enrolled and LS and tricuspid annual plane systolic excursion (TAPSE)were determined before discharge with Fibroscan® and Echocardiography. The patients were divided into two groups: High LS group(LS >6.9Kpa, n=23) and Low LS group(LS ≤6.9Kp, n=30) . Patients were followed up for 24 months at interval of 3 months. The endpoint of follow-up is death or rehospitalization for HF. Results. All patients were followed up for 24 months or until the endpoint. Patients in High LS group had lower platelet count(P=0.014), lower creatine clear rate (P=0.014), higher level of B-type natriuretic peptide at discharge(P=0.012), and lower tricuspid annual plane systolic excursion (P<0.001). During 24 months follow-up, 3(5.7%) deaths and 21(39.6%) hospitalization were observed. Patients in high LS group had a higher rate of death/rehospitalization when compared with patient in low LS group (Hazard ratio: 4.81; 95% confidence interval:1.69-13.7, P=0.003) after adjustment for age, sex, platelet count, creatine clear rate, and B-type natriuretic peptide level. Also, TAPSE≤16 can predict adverse cardiac events with HR of 6.63 (95% confidence interval:1.69-13.7, P=0.004) for age, sex, platelet count, creatine clear rate, and B-type natriuretic peptide level.Conclusion. LS and TAPSE may be considered for predicting worse outcomes for patients with heart failure.

Cystatin C, a Novel Measure of Renal Function, Is an Independent Predictor of Cardiac Events in Patients With Heart Failure

2005 ◽  
Vol 11 (8) ◽  
pp. 595-601 ◽  
Author(s):  
Takanori Arimoto ◽  
Yasuchika Takeishi ◽  
Takeshi Niizeki ◽  
Noriaki Takabatake ◽  
Hidenobu Okuyama ◽  
...  
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Cystatin C ◽  
Independent Predictor ◽  
Cardiac Events ◽  
Patients With Heart Failure
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