Cilnidipine, a N+L-type dihydropyridine ca channel blocker, suppresses the occurrence of ventricular premature arrythmia during ischemia and reperfusion in rabbits

2004 ◽  
Vol 10 (5) ◽  
pp. S165
Author(s):  
Nagai Hiroshi ◽  
Minatoguchi Shinya ◽  
Hirohito Onogi ◽  
Chen Xuehai ◽  
Maruyama Rumiko ◽  
...  
Keyword(s):  
Channel Blocker ◽  
Ischemia And Reperfusion ◽  
Ca Channel

scholarly journals Pheochromocytoma and Ca++ channel blocker.

1986 ◽  
Vol 27 (3) ◽  
pp. 429-436 ◽  
Author(s):  
Akihisa TOMARU ◽  
Kinjo OH ◽  
Yoshitaro MIURA ◽  
Hitoshi NAKAMURA ◽  
Makoto YOSHIKAWA ◽  
...  
Keyword(s):  
Channel Blocker ◽  
Ca Channel

scholarly journals Role of protein kinase C in Ca channel blocker-induced renal arteriolar dilation in spontaneously hypertensive rats

2005 ◽  
Vol 54 (2) ◽  
pp. 102-108 ◽  
Author(s):  
Koichi Hayashi ◽  
Shu Wakino ◽  
Yuri Ozawa ◽  
Koichiro Homma ◽  
Takeshi Kanda ◽  
...  
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Spontaneously Hypertensive Rats ◽  
Channel Blocker ◽  
Ca Channel ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Kinase C

scholarly journals Effects of a dual L/N-type Ca channel blocker, cilnidipine, on neural regulations of heart rate in anesthetized dogs.

1999 ◽  
Vol 79 ◽  
pp. 179
Author(s):  
Tomoyuki Konda ◽  
Akira Takahara ◽  
Hideki Dohmoto ◽  
Kazutoshi Maeda ◽  
Ryota Yoshimoto
Keyword(s):  
Heart Rate ◽  
Channel Blocker ◽  
Ca Channel ◽  
Anesthetized Dogs

Differential role of sarcolemmal and mitochondrial KATP channels in adenosine-enhanced ischemic preconditioning

2000 ◽  
Vol 279 (6) ◽  
pp. H2694-H2703 ◽  
Author(s):  
Yoshiya Toyoda ◽  
Ingeborg Friehs ◽  
Robert A. Parker ◽  
Sidney Levitsky ◽  
James D. McCully
Keyword(s):  
Infarct Size ◽  
Functional Recovery ◽  
Ischemic Preconditioning ◽  
Channel Blocker ◽  
Katp Channels ◽  
Size Reduction ◽  
Ischemia And Reperfusion ◽  
Infarct Size Reduction ◽  
Mitochondrial Katp Channels

Adenosine-enhanced ischemic preconditioning (APC) extends the protection afforded by ischemic preconditioning (IPC) by both significantly decreasing infarct size and significantly enhancing postischemic functional recovery. The purpose of this study was to determine whether APC is modulated by ATP-sensitive potassium (KATP) channels and to determine whether this modulation occurs before ischemia or during reperfusion. The role of KATP channels before ischemia (I), during reperfusion (R), or during ischemia and reperfusion (IR) was investigated using the nonspecific KATP blocker glibenclamide (Glb), the mitochondrial (mito) KATP channel blocker 5-hydroxydecanoate (5-HD), and the sarcolemmal (sarc) KATPchannel blocker HMR-1883 (HMR). Infarct size was significantly increased ( P < 0.05) in APC hearts with Glb-I, Glb-R, and 5-HD-I treatment and partially with 5-HD-R. Glb-I and Glb-R treatment significantly decreased APC functional recovery ( P < 0.05 vs. APC), whereas 5-HD-I and 5-HD-R had no effect on APC functional recovery. HMR-IR significantly decreased postischemic functional recovery ( P < 0.05 vs. APC) but had no effect on infarct size. These data indicate that APC infarct size reduction is modulated by mitoKATP channels primarily during ischemia and suggest that functional recovery is modulated by sarcKATP channels during ischemia and reperfusion.

EFFECT OF A Ca++ CHANNEL BLOCKER ON CEREBRAL REFLOW PHENOMENON IN THE DOG

1982 ◽  
Vol 57 (3) ◽  
pp. A363-A363 ◽  
Author(s):  
S. D. Gergis ◽  
M. D. Sokoll ◽  
S. M. Sarracino ◽  
N. F. Kassell
Keyword(s):  
Channel Blocker ◽  
Ca Channel

scholarly journals Effects of L- and N-Type Ca Channel Blocker Cilnidipine on Changes in Heart Rate and QT Interval During Dialysis

2017 ◽  
Vol 42 (5) ◽  
pp. 933-941
Author(s):  
Takeshi Iida ◽  
Satoshi Morimoto ◽  
Yoshifumi Amari ◽  
Takashi Ando ◽  
Atsuhiro Ichihara
Keyword(s):  
Heart Rate ◽  
Qt Interval ◽  
Channel Blocker ◽  
Ca Channel

Ca-channel blocker-induced gingival overgrowth that improved with non-surgical therapy during visiting care: a case report

Gerodontology ◽  
2015 ◽  
Vol 32 (4) ◽  
pp. 318-320 ◽  
Author(s):  
Tomotaka Kato ◽  
Hiroya Takiuchi ◽  
Masahiro Yamaguchi ◽  
Toru Naito
Keyword(s):  
Case Report ◽  
Surgical Therapy ◽  
Channel Blocker ◽  
Ca Channel ◽  
Gingival Overgrowth
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