The PI3K/Akt/mTOR signaling pathway mediates insulin-like growth factor 1-induced E-cadherin down-regulation and cell proliferation in ovarian cancer cells

Man-Tat Lau; Peter C.K. Leung

doi:10.1016/j.canlet.2012.08.016

The PI3K/Akt/mTOR signaling pathway mediates insulin-like growth factor 1-induced E-cadherin down-regulation and cell proliferation in ovarian cancer cells

Cancer Letters ◽

10.1016/j.canlet.2012.08.016 ◽

2012 ◽

Vol 326 (2) ◽

pp. 191-198 ◽

Cited By ~ 80

Author(s):

Man-Tat Lau ◽

Peter C.K. Leung

Keyword(s):

Ovarian Cancer ◽

Cell Proliferation ◽

Growth Factor ◽

Cancer Cells ◽

Signaling Pathway ◽

Mtor Signaling ◽

Ovarian Cancer Cells ◽

Insulin Like Growth Factor ◽

Mtor Signaling Pathway ◽

Down Regulation

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MiR-206 inhibits epithelial ovarian cancer cells growth and invasion via blocking c-Met/AKT/mTOR signaling pathway

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2018.05.077 ◽

2018 ◽

Vol 104 ◽

pp. 763-770 ◽

Cited By ~ 30

Author(s):

Chunxiu Dai ◽

Yongyong Xie ◽

Xiaoping Zhuang ◽

Zhengzhong Yuan

Keyword(s):

Ovarian Cancer ◽

Epithelial Ovarian Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Mtor Signaling ◽

Ovarian Cancer Cells ◽

Mtor Signaling Pathway

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Hyperactivation of the Insulin-like Growth Factor Receptor I Signaling Pathway Is an Essential Event for Cisplatin Resistance of Ovarian Cancer Cells

Cancer Research ◽

10.1158/0008-5472.can-08-3153 ◽

2009 ◽

Vol 69 (7) ◽

pp. 2996-3003 ◽

Cited By ~ 111

Author(s):

Niels Eckstein ◽

Kati Servan ◽

Barbara Hildebrandt ◽

Anne Pölitz ◽

Georg von Jonquières ◽

...

Keyword(s):

Ovarian Cancer ◽

Growth Factor ◽

Cancer Cells ◽

Signaling Pathway ◽

Cisplatin Resistance ◽

Growth Factor Receptor ◽

Ovarian Cancer Cells ◽

Insulin Like Growth Factor

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Antisense phosphorothioate oligodeoxynucleotide down-regulation of the insulin-like growth factor I receptor in ovarian cancer cells

International Journal of Cancer ◽

10.1002/(sici)1097-0215(19980812)77:4<567::aid-ijc16>3.0.co;2-3 ◽

1998 ◽

Vol 77 (4) ◽

pp. 567-571 ◽

Cited By ~ 24

Author(s):

Markus Müller ◽

Manfred Dietel ◽

Andreas Turzynski ◽

Kai Wiechen

Keyword(s):

Ovarian Cancer ◽

Growth Factor ◽

Cancer Cells ◽

Ovarian Cancer Cells ◽

Insulin Like Growth Factor ◽

Down Regulation ◽

Factor I ◽

Growth Factor I

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LSD1 negatively regulates autophagy through the mTOR signaling pathway in ovarian cancer cells

Oncology Reports ◽

10.3892/or.2018.6432 ◽

2018 ◽

Cited By ~ 1

Author(s):

Ye Wei ◽

Tiantian Han ◽

Ranran Wang ◽

Jing Wei ◽

Ke Peng ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Mtor Signaling ◽

Ovarian Cancer Cells ◽

Mtor Signaling Pathway

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Resveratrol inhibits the proliferation and induces the apoptosis in ovarian cancer cells via inhibiting glycolysis and targeting AMPK/mTOR signaling pathway

Journal of Cellular Biochemistry ◽

10.1002/jcb.26822 ◽

2018 ◽

Vol 119 (7) ◽

pp. 6162-6172 ◽

Cited By ~ 30

Author(s):

Yu Liu ◽

Lin Tong ◽

Yan Luo ◽

Xin Li ◽

Gaowen Chen ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Mtor Signaling ◽

Ovarian Cancer Cells ◽

Mtor Signaling Pathway

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[Corrigendum] LSD1 negatively regulates autophagy through the mTOR signaling pathway in ovarian cancer cells

Oncology Reports ◽

10.3892/or.2018.6495 ◽

2018 ◽

Author(s):

Ye Wei ◽

Tiantian Han ◽

Ranran Wang ◽

Jing Wei ◽

Ke Peng ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Mtor Signaling ◽

Ovarian Cancer Cells ◽

Mtor Signaling Pathway

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Knockdown of Hypoxia-Inducible Factor 1α (HIF-1α) Promotes Autophagy and Inhibits Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Ovarian Cancer Cells

Medical Science Monitor ◽

10.12659/msm.915730 ◽

2019 ◽

Vol 25 ◽

pp. 4250-4263 ◽

Cited By ~ 3

Author(s):

Jinling Huang ◽

Likun Gao ◽

Bingshu Li ◽

Cheng Liu ◽

Shasha Hong ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Mammalian Target Of Rapamycin ◽

Hypoxia Inducible Factor ◽

Mtor Signaling ◽

Ovarian Cancer Cells ◽

Mtor Signaling Pathway ◽

Phosphatidylinositol 3 Kinase ◽

Hypoxia Inducible Factor 1Α

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Polypeptide LTX‐315 reverses the cisplatin chemoresistance of ovarian cancer cells via regulating Beclin‐1/PI3K/mTOR signaling pathway

Journal of Biochemical and Molecular Toxicology ◽

10.1002/jbt.22853 ◽

2021 ◽

Author(s):

Jian Ma ◽

Lei Liu ◽

Yang Ling ◽

Jianhua Zheng

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Mtor Signaling ◽

Beclin 1 ◽

Ovarian Cancer Cells ◽

Mtor Signaling Pathway ◽

Cisplatin Chemoresistance

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Anticancer Activity of Metformin, an Antidiabetic Drug, Against Ovarian Cancer Cells Involves Inhibition of Cysteine-Rich 61 (Cyr61)/Akt/Mammalian Target of Rapamycin (mTOR) Signaling Pathway

Medical Science Monitor ◽

10.12659/msm.909745 ◽

2018 ◽

Vol 24 ◽

pp. 6093-6101 ◽

Cited By ~ 2

Author(s):

Fengli Zhang ◽

Huixiao Chen ◽

Jing Du ◽

Bin Wang ◽

Lixiao Yang

Keyword(s):

Ovarian Cancer ◽

Anticancer Activity ◽

Cancer Cells ◽

Signaling Pathway ◽

Mammalian Target Of Rapamycin ◽

Mtor Signaling ◽

Target Of Rapamycin ◽

Ovarian Cancer Cells ◽

Mtor Signaling Pathway ◽

Antidiabetic Drug

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Retracted: Anticancer Activity of Metformin, an Antidiabetic Drug, Against Ovarian Cancer Cells Involves Inhibition of Cysteine-Rich 61 (Cyr61)/Akt/Mammalian Target of Rapamycin (mTOR) Signaling Pathway

Medical Science Monitor ◽

10.12659/msm.932331 ◽

2021 ◽

Vol 27 ◽

Author(s):

Fengli Zhang ◽

Huixiao Chen ◽

Jing Du ◽

Bin Wang ◽

Lixiao Yang

Keyword(s):

Ovarian Cancer ◽

Anticancer Activity ◽

Cancer Cells ◽

Signaling Pathway ◽

Mammalian Target Of Rapamycin ◽

Mtor Signaling ◽

Target Of Rapamycin ◽

Ovarian Cancer Cells ◽

Mtor Signaling Pathway ◽

Antidiabetic Drug

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