Primary liver cancer incidence and survival in ethnic groups in England, 2001–2007

2013 ◽  
Vol 37 (1) ◽  
pp. 34-38 ◽  
Author(s):  
Ruth H. Jack ◽  
Julie Konfortion ◽  
Victoria H. Coupland ◽  
Hemant M. Kocher ◽  
David P. Berry ◽  
...  
Livers ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 49-59
Author(s):  
Philavanh Sitbounlang ◽  
Agnès Marchio ◽  
Eric Deharo ◽  
Phimpha Paboriboune ◽  
Pascal Pineau

Laos is a landlocked country in South East Asia, ranking fifth for primary liver cancer incidence worldwide. Risk factors that might explain this worrying situation are poorly known. We conducted a review of the literature concerning the etiologies of terminal liver diseases in Laos. A double infectious burden with hepatitis B and C viruses and the liver fluke Opisthorchis viverrini seems to be the main cause of the high liver cancer incidence. Moreover, it was also suggested that mutagenic substances frequently found in tobacco, alcoholic beverages, fermented fish, and mold-contaminated cereals or nuts, which are all substances heavily consumed by Lao people, lead to the accumulation of DNA mutations in the liver cell genome causing tumor processes. However, the respective proportions of liver cancer cases attributable to each category of infections and substances consumed, as well as the histological nature of the neoplasia are still not precisely documented in Laos. The international medical and scientific communities as well as public health stakeholders should urgently consider the alarming situation of liver health in Laos to stimulate both research and subsequent implementation of prevention policies.


Cancer ◽  
2008 ◽  
Vol 113 (S5) ◽  
pp. 1244-1255 ◽  
Author(s):  
Melissa A. Jim ◽  
David G. Perdue ◽  
Lisa C. Richardson ◽  
David K. Espey ◽  
John T. Redd ◽  
...  

2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Marie Pedersen* ◽  
Zorana J Andersen ◽  
Mette Sørensen ◽  
Andrea Jaensch ◽  
Fulvio Ricceri ◽  
...  

2017 ◽  
Vol 154 ◽  
pp. 226-233 ◽  
Author(s):  
Marie Pedersen ◽  
Zorana J. Andersen ◽  
Massimo Stafoggia ◽  
Gudrun Weinmayr ◽  
Claudia Galassi ◽  
...  

2013 ◽  
Vol 22 (5) ◽  
pp. 448-454 ◽  
Author(s):  
Jing Gao ◽  
Li Xie ◽  
Wan-Qing Chen ◽  
Si-Wei Zhang ◽  
Qi-Jun Wu ◽  
...  

Author(s):  
Audrius Dulskas ◽  
Povilas Kavaliauskas ◽  
Kestutis Zagminas ◽  
Ligita Jancoriene ◽  
Giedre Smailyte

Background: Recently, reports have suggested that rates of liver cancer have increased during the last decades in developed countries; increasing hepatocellular carcinoma and cholangiocarcinoma rates were reported. The aim of this study was to examine time trends in incidence and mortality rates of liver cancer for the period of 1998–2015 in Lithuania by sex, age, and histology. Methods: We examined the incidence of liver cancer from 1998 to 2015 using data from the Lithuanian Cancer Registry. Age-standardized incidence rates were calculated by sex, age, and histology. Trends were analyzed using the Joinpoint Regression Program to estimate the annual percent change. Results: A total of 3086 primary liver cancer cases were diagnosed, and 2923 patients died from liver cancer. The total number of liver cancer cases changed from 132 in 1998 to 239 in 2015. Liver cancer incidence rates changed during the study period from 5.02/100,000 in 1998 to 10.54/100,000 in 2015 in men and from 2.43/100,000 in 1998 to 6.25/100,000 in 2015 in women. Annual percentage changes (APCs) in the age-standardized rates over this period were 4.5% for incidence and 3.6% for mortality. Hepatocellular cancer incidence rates were stable from 1998 to 2005 (APC −5.9, p = 0.1) and later increased by 6.7% per year (p < 0.001). Intrahepatic ductal carcinoma incidence increased by 8.9% per year throughout the study period. The rise in incidence was observed in all age groups; however, in age groups < 50 and between 70 and 79 years, observed changes were not statistically significant. For mortality, the significant point of trend change was detected in 2001, where after stable mortality, rates started to increase by 2.4% per year. Conclusions: Primary liver cancer incidence and mortality increased in both sexes in Lithuania. The rise om incidence was observed in both sexes and main histology groups. The increasing incidence trend may be related to the prevalence of main risk factors (alcohol consumption, hepatitis B and C infections. and diabetes).


BMC Cancer ◽  
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Wenyi Liu ◽  
Qing Liu ◽  
Qihong Huang ◽  
Yuqiang Lu ◽  
Shanghang Xie ◽  
...  

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