A modeling strategy for cell dynamic morphology classification based on local deformation patterns

2019 ◽  
Vol 54 ◽  
pp. 101587 ◽  
Author(s):  
Heng Li ◽  
Fengqian Pang ◽  
Zhiwen Liu
Author(s):  
Paul Briant ◽  
Scott Bevill ◽  
Thomas P. Andriacchi

Mechanical loads have been shown in numerous studies to affect the health of articular cartilage [1]. Regional variations in the local deformation within articular cartilage under both normal and abnormal loading are, however, poorly understood. Understanding these deformation patterns is important, since conditions such as anterior cruciate ligament injury have been suggested to initiate cartilage breakdown by shifting the regions of frequent loading within the joint [2]. Quantifying variations in the deformation behavior of the collagen matrix in cartilage under load will therefore provide insight into the mechanical environment within cartilage and test the feasibility of a kinematic pathway to the initiation of osteoarthritis (OA). The objective of this study was to test the hypothesis that the collagen matrix in two regions of cartilage that normally experience different applied loads will deform differently under the same applied load.


Author(s):  
Arman U. Ahmed ◽  
Sreekanta Das ◽  
J. J. Roger Cheng

Steel pipelines, buried in cold regions, often respond to thermal strains and/or geotechnical movement caused by factors such as thaw settlement, frost heave, and slope instability. These complex field conditions can impose large displacements on these pipelines, resulting in localized wrinkles well into the plastic range of the pipe material. Eventually, there is a possibility of a fracture occurring at a wrinkled location under continuous deformation. A recent field fracture and a failed laboratory specimen have been observed within a telescopic wrinkle under tearing action and the loading histories have been found to be monotonic, without significant strain reversals. These incidents underscore the need for a detailed investigation, which seeks to answer fundamental questions regarding this unique mode of failure. In this study, a finite element model has been developed, which is capable of accounting for material nonlinearity effects, large displacements, large rotations, initial imperfections, and possible complex contact surfaces. Based on limited test data, the comparison of the numerical and the experimental results demonstrates the ability of the present model to predict the local buckling behavior of pipes when deformed well into the postwrinkling range. The results of this analytical work include the global and local deformation patterns and a detailed assessment of the stress-strain relations at the region of the telescopic wrinkle. The results obtained from this study have recognized the occurrence of strain reversal at the sharp fold of the wrinkle on the compression side of the pipe, a phenomenon that could be considered to be the key factor for triggering this unique failure mechanism.


Author(s):  
Todd C. Doehring

Deformation, crimp, and alignment patterns of collagen fibers in soft tissues have been measured using a novel testing system combining controlled loading with synchronized high-resolution imaging. Marker-less feature tracking was used to measure 2-D local deformations, and a radon transform was used to compute quantitative maps of crimp patterns and local tissue fiber orientation. We found highly nonuniform deformation and crimp patterns, with the highest strains near the clamps, and the lowest strains in the midsubstance region.


2012 ◽  
Vol 19 (4) ◽  
pp. 515-525 ◽  
Author(s):  
Pawel Woelke ◽  
Najib Abboud ◽  
Darren Tennant ◽  
Eric Hansen ◽  
Chad Mcarthur

The current paper presents the results of a ship impact study conducted using various analytical approaches available in the literature with the results obtained from detailed finite element analysis. Considering a typical container vessel impacting a rigid wall with an initial speed of 10 knots, the study investigates the forces imparted on the struck obstacle, the energy dissipated through inelastic deformation, penetration, local deformation patterns, and local failure of the ship elements. The main objective of the paper is to study the accuracy and generality of the predictions of the vessel collision forces, obtained by means of analytical closed-form solutions, in reference to detailed finite element analyses. The results show that significant discrepancies between simplified analytical approaches and detailed finite element analyses can occur, depending on the specific impact scenarios under consideration.


Author(s):  
D. L. Callahan

Modern polishing, precision machining and microindentation techniques allow the processing and mechanical characterization of ceramics at nanometric scales and within entirely plastic deformation regimes. The mechanical response of most ceramics to such highly constrained contact is not predictable from macroscopic properties and the microstructural deformation patterns have proven difficult to characterize by the application of any individual technique. In this study, TEM techniques of contrast analysis and CBED are combined with stereographic analysis to construct a three-dimensional microstructure deformation map of the surface of a perfectly plastic microindentation on macroscopically brittle aluminum nitride.The bright field image in Figure 1 shows a lg Vickers microindentation contained within a single AlN grain far from any boundaries. High densities of dislocations are evident, particularly near facet edges but are not individually resolvable. The prominent bend contours also indicate the severity of plastic deformation. Figure 2 is a selected area diffraction pattern covering the entire indentation area.


2018 ◽  
Vol 46 (2) ◽  
pp. 78-92 ◽  
Author(s):  
A. I. Kubba ◽  
G. J. Hall ◽  
S. Varghese ◽  
O. A. Olatunbosun ◽  
C. J. Anthony

ABSTRACT This study presents an investigation of the inner tire surface strain measurement by using piezoelectric polymer transducers adhered on the inner liner of the tire, acting as strain sensors in both conventional and dual-chamber tires. The piezoelectric elements generate electrical charges when strain is applied. The inner liner tire strain can be found from the generated charge. A wireless data logger was employed to measure and transmit the measured signals from the piezoelectric elements to a PC to store and display the readout signals in real time. The strain data can be used as a monitoring system to recognize tire-loading conditions (e.g., traction, braking, and cornering) in smart tire technology. Finite element simulations, using ABAQUS, were employed to estimate tire deformation patterns in both conventional and dual-chamber tires for pure rolling and steady-state cornering conditions for different inflation pressures to simulate on-road and off-road riding tire performances and to compare with the experimental results obtained from both the piezoelectric transducers and tire test rig.


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