Internal model sliding mode control approach for glucose regulation in type 1 diabetes

2010 ◽  
Vol 5 (2) ◽  
pp. 94-102 ◽  
Author(s):  
Amjad Abu-Rmileh ◽  
Winston Garcia-Gabin ◽  
Darine Zambrano
Keyword(s):  
Type 1 Diabetes ◽  
Sliding Mode Control ◽  
Internal Model ◽  
Sliding Mode ◽  
Glucose Regulation ◽  
Control Approach ◽  
Mode Control

A sliding mode control approach for patients with type 1 diabetes

2017 ◽  
Author(s):  
Eduardo Alvaro ◽  
Sebastian Rivadeneira ◽  
Danilo Chavez ◽  
Oscar Camacho ◽  
Pablo S. Rivadeneira
Keyword(s):  
Type 1 Diabetes ◽  
Sliding Mode Control ◽  
Sliding Mode ◽  
Control Approach ◽  
Mode Control

scholarly journals Glucose–insulin stabilization in type-1 diabetic patient: A uniform exact differentiator–based robust integral sliding mode control approach

2019 ◽  
Vol 15 (3) ◽  
pp. 155014771983357 ◽  
Author(s):  
Waqar Alam ◽  
Qudrat Khan ◽  
Raja Ali Riaz ◽  
Rini Akmeliawati
Keyword(s):  
Sliding Mode Control ◽  
Diabetic Patient ◽  
Sliding Mode ◽  
Control Law ◽  
Integral Sliding Mode Control ◽  
Integral Sliding Mode ◽  
Control Approach ◽  
Model Based ◽  
Mode Control

Diabetes mellitus is a persistent metabolic syndrome caused by impaired capability of the body’s production and usage of insulin. This impaired capability results in chronic hyperglycaemia, the elevated glucose concentration in the bloodstream, which may lead to many incurable complications. To escape this dire situation, a proper model-based exogenous infusion of insulin bolus is required, which is usually established via different feedback control strategies. In this article, the authors present a mathematical model–based robust integral sliding mode control approach for stabilization of internal glucose–insulin regulatory system in type-1 diabetic patient. Since the state variables of the system are not directly available to the controller, a uniform exact differentiator observer is employed to accomplish the aforementioned task. In the proposed control law, the incorporation of integral term in the switching manifold eliminates the reaching phase, which causes the sliding mode to establish from the very initial point, thus enhances the robustness property of the proposed control scheme. Moreover, the chattering problem is also substantially suppressed to a considerable extent along a defined manifold. To verify the theoretical analysis, the proposed control law is verified via computer simulations which demonstrate the effectiveness of the proposed control law against the external perturbations, that is, unannounced meal intake and physical exercise.

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