Mammillary body alterations and spatial memory impairment in Wistar rats with thioacetamide-induced cirrhosis

2008 ◽  
Vol 1233 ◽  
pp. 185-195 ◽  
Author(s):  
Marta Méndez ◽  
Magdalena Méndez-López ◽  
Laudino Lopez ◽  
María A. Aller ◽  
Jaime Arias ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Memory Impairment ◽  
Wistar Rats ◽  
Mammillary Body

scholarly journals Reduction of Phosphorylated Synapsin I (Ser-553) Leads to Spatial Memory Impairment by Attenuating GABA Release after Microwave Exposure in Wistar Rats

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e95503 ◽  
Author(s):  
Simo Qiao ◽  
Ruiyun Peng ◽  
Haitao Yan ◽  
Yabing Gao ◽  
Changzhen Wang ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Memory Impairment ◽  
Wistar Rats ◽  
Gaba Release ◽  
Synapsin I ◽  
Microwave Exposure

scholarly journals Effects of Ficus umbellata (Moraceae) Aqueous Extract and 7-Methoxycoumarin on Scopolamine-Induced Spatial Memory Impairment in Ovariectomized Wistar Rats

2018 ◽  
Vol 2018 ◽  
pp. 1-14 ◽  
Author(s):  
Stéphane Zingue ◽  
Harquin Simplice Foyet ◽  
Sefirin Djiogue ◽  
Yannick Ezo’o Ezo’o ◽  
Hervé Hervé Ngatanko Abaïssou ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Aqueous Extract ◽  
Memory Impairment ◽  
Wistar Rats ◽  
Reference Memory ◽  
Ovariectomized Rats ◽  
Estradiol Valerate ◽  
Memory Errors ◽  
Neuroprotective Effects ◽  
Before And After

The present work was undertaken to evaluate the ability of F. umbellata aqueous extract and its major component 7-methoxycoumarin (MC) to improve scopolamine-induced spatial memory impairment in ovariectomized Wistar rats. For this to be done, 10 sham-operated and 30 postmenopausal-like rats were randomly distributed in eight groups (n=5) and treated with distilled water (2 mL/250 g), estradiol valerate (1 mg/kg BW), piracetam (1.5 mg/kg BW), F. umbellata aqueous extract (50 and 200 mg/kg BW), or MC (1 mg/kg BW) for 21 consecutive days. Before and after the memory impairment with scopolamine (2 mg/kg BW), animals underwent behavioral evaluations on Y- and radial mazes. As results, age and ovariectomy did not induce significant changes in the reference memory errors. While age decreased working memory errors, ovariectomy increased it. The MC as well as F. umbellata extract significantly increased (p<0.01) the percentage of spontaneous alternation and decreased (p<0.001) working and spatial reference memory errors and anxiety parameters (rearing and grooming) in ovariectomized rats. MC significantly reduced (p<0.05) the MDA level, but resulted in an increase in GSH level in brain homogenates. These results suggest that MC is endowed with neuroprotective effects and could account for the neuroprotective effects of F. umbellata in rats.

Geraniol improved memory impairment and neurotoxicity induced by zinc oxide nanoparticles in male wistar rats through its antioxidant effect

Life Sciences ◽  
2021 ◽  
pp. 119823
Author(s):  
Maryam Farokhcheh ◽  
Leilabeigom Hejazian ◽  
Zeinab Akbarnejad ◽  
Fereshteh Pourabdolhossein ◽  
Seyed Mohammad Hosseini ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Memory Impairment ◽  
Wistar Rats ◽  
Antioxidant Effect ◽  
Oxide Nanoparticles ◽  
Male Wistar Rats
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