Gonadal hormone regulation of glial fibrillary acidic protein immunoreactivity in the medial amygdala subnuclei across the estrous cycle and in castrated and treated female rats

2006 ◽  
Vol 1108 (1) ◽  
pp. 117-126 ◽  
Author(s):  
Flávia G. Martinez ◽  
Erica E.S. Hermel ◽  
Léder L. Xavier ◽  
Giordano G. Viola ◽  
João Riboldi ◽  
...  
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Estrous Cycle ◽  
Acidic Protein ◽  
Female Rats ◽  
Gonadal Hormone ◽  
Medial Amygdala ◽  
Hormone Regulation ◽  
Protein Immunoreactivity

Glial fibrillary acidic protein immunodetection and immunoreactivity in the anterior and posterior medial amygdala of male and female rats

2002 ◽  
Vol 58 (1) ◽  
pp. 67-75 ◽  
Author(s):  
Alberto A Rasia-Filho ◽  
Léder L Xavier ◽  
Paula dos Santos ◽  
Günther Gehlen ◽  
Matilde Achaval
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Acidic Protein ◽  
Female Rats ◽  
Medial Amygdala ◽  
Male And Female ◽  
Male And Female Rats

Neocortical and Hippocampal Glial Fibrillary Acidic Protein Immunoreactivity Shows Region-Specific Variation during the Mouse Estrous Cycle

2006 ◽  
Vol 83 (5-6) ◽  
pp. 325-335 ◽  
Author(s):  
Robert G. Struble ◽  
Seema Afridi ◽  
Shari Beckman-Randall ◽  
Miao Li ◽  
Craig Cady ◽  
...  
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Estrous Cycle ◽  
Acidic Protein ◽  
Specific Variation ◽  
Protein Immunoreactivity

Sex and estrous cycle-dependent differences in glial fibrillary acidic protein immunoreactivity in the adult rat hippocampus

2009 ◽  
Vol 55 (1) ◽  
pp. 257-263 ◽  
Author(s):  
Clorinda Arias ◽  
Angélica Zepeda ◽  
Karina Hernández-Ortega ◽  
Perla Leal-Galicia ◽  
Cinthia Lojero ◽  
...  
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Estrous Cycle ◽  
Acidic Protein ◽  
Rat Hippocampus ◽  
Adult Rat ◽  
Protein Immunoreactivity ◽  
Cycle Dependent

The anorectic effect of fenfluramine is influenced by sex and stage of the estrous cycle in rats

2005 ◽  
Vol 288 (6) ◽  
pp. R1486-R1491 ◽  
Author(s):  
Lisa A. Eckel ◽  
Heidi M. Rivera ◽  
Deann P. D. Atchley
Keyword(s):  
Food Intake ◽  
Estrous Cycle ◽  
Female Rats ◽  
Male Rats ◽  
Gonadal Hormone ◽  
Estrous Female ◽  
Male And Female Rats ◽  
Daily Food ◽  
Hormone Status ◽  
Anorectic Effect

The controls of food intake differ in male and female rats. Daily food intake is typically greater in male rats, relative to female rats, and a decrease in food intake, coincident with the estrous stage of the ovarian reproductive cycle, is well documented in female rats. This estrous-related decrease in food intake has been attributed to a transient increase in the female rat's sensitivity to satiety signals generated during feeding bouts. Here, we investigated whether sex or stage of the estrous cycle modulate the satiety signal generated by fenfluramine, a potent serotonin (5-HT) releasing agent. To examine this hypothesis, food intake was monitored in male, diestrous female, and estrous female rats after intraperitoneal injections of 0, 0.25, and 1.0 mg/kg d-fenfluramine. The lower dose of fenfluramine decreased food intake only in diestrous and estrous females, suggesting that the minimally effective anorectic dose of fenfluramine is lower in female rats, relative to male rats. Although the larger dose of fenfluramine decreased food intake in both sexes, the duration of anorexia was greater in diestrous and estrous female rats, relative to male rats. Moreover, the magnitude of the anorectic effect of the larger dose of fenfluramine was greatest in estrous rats, intermediate in diestrous rats, and least in male rats. Thus our findings indicate that the anorectic effect of fenfluramine is modulated by gonadal hormone status.

Maternal food restriction in rats of the F0 generation increases retroperitoneal fat, the number and size of adipocytes and induces periventricular astrogliosis in female F1 and male F2 generations

2017 ◽  
Vol 29 (7) ◽  
pp. 1340 ◽  
Author(s):  
A. O. Joaquim ◽  
C. P. Coelho ◽  
P. Dias Motta ◽  
L. F. Felício ◽  
E. F. Bondan ◽  
...  
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Food Restriction ◽  
Bodyweight Gain ◽  
Male Offspring ◽  
Acidic Protein ◽  
Female Rats ◽  
Juvenile Period ◽  
Gfap Expression ◽  
F2 Generation ◽  
F1 Generation

The present study investigated whether male offspring (F2 generation) from female rats (F1 generation) whose mothers (F0 generation) were food restricted during gestation inherit a phenotypic transgenerational tendency towards being overweight and obese in the juvenile period, in the absence of food restriction in the F1/F2 generations. Dams of the F0 generation were 40% food restricted during pregnancy. Bodyweight, the number and size of larger and small hypodermal adipocytes (HAs), total retroperitoneal fat (RPF) weight and the expression of glial fibrillary acidic protein (GFAP) in periventricular hypothalamic astrocytes (PHAs), as determined by immunohistochemistry, were evaluated in both generations. In the female F1 generation, there was low bodyweight gain only during the juvenile period (30–65 days of age), a decrease in the size of small adipocytes, an increase in the number of small adipocytes, an increase in RPF weight and an increase in GFAP expression in PHAs at 90–95 days of age. In males of the F2 generation at 50 days of age, there was increased bodyweight and RPF weight, and a small number of adipocytes and GFAP expression in PHAs. These data indicate that the phenotypic transgenerational tendency towards being overweight and obese was observed in females (F1) from mothers (F0) that were prenatally food restricted was transmitted to their male offspring.

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