In vivo imaging of apoptosis in patients with acute stroke: Correlation with blood–brain barrier permeability

2006 ◽  
Vol 1103 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Mordechai Lorberboym ◽  
Francis G. Blankenberg ◽  
Menahem Sadeh ◽  
Yair Lampl
Keyword(s):  
Acute Stroke ◽  
Blood Brain Barrier ◽  
In Vivo Imaging ◽  
Brain Barrier ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Blood Brain ◽  
Brain Barrier Permeability

scholarly journals Dynamic in vivo imaging of cerebral blood flow and blood–brain barrier permeability

NeuroImage ◽  
2010 ◽  
Vol 49 (1) ◽  
pp. 337-344 ◽  
Author(s):  
Ofer Prager ◽  
Yoash Chassidim ◽  
Chen Klein ◽  
Haviv Levi ◽  
Ilan Shelef ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Blood Brain Barrier ◽  
In Vivo Imaging ◽  
Brain Barrier ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Blood Brain ◽  
Brain Barrier Permeability

scholarly journals Blood-brain barrier permeability imaging using perfusion computed tomography

2015 ◽  
Vol 49 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Jernej Avsenik ◽  
Sotirios Bisdas ◽  
Katarina Surlan Popovic
Keyword(s):  
Computed Tomography ◽  
Acute Stroke ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Microvascular Endothelium ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Perfusion Computed Tomography ◽  
Blood Brain ◽  
Brain Barrier Permeability

Abstract Background. The blood-brain barrier represents the selective diffusion barrier at the level of the cerebral microvascular endothelium. Other functions of blood-brain barrier include transport, signaling and osmoregulation. Endothelial cells interact with surrounding astrocytes, pericytes and neurons. These interactions are crucial to the development, structural integrity and function of the cerebral microvascular endothelium. Dysfunctional blood-brain barrier has been associated with pathologies such as acute stroke, tumors, inflammatory and neurodegenerative diseases. Conclusions. Blood-brain barrier permeability can be evaluated in vivo by perfusion computed tomography - an efficient diagnostic method that involves the sequential acquisition of tomographic images during the intravenous administration of iodinated contrast material. The major clinical applications of perfusion computed tomography are in acute stroke and in brain tumor imaging.

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