Juvenile myoclonic epilepsy: Long-term prognosis and risk factors

2021 ◽  
Author(s):  
Nicola Pietrafusa ◽  
Angela La Neve ◽  
Luca de Palma ◽  
Giovanni Boero ◽  
Concetta Luisi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Juvenile Myoclonic Epilepsy ◽  
Myoclonic Epilepsy ◽  
Long Term Prognosis

Long-term prognosis of typical childhood absence epilepsy: Remission or progression to juvenile myoclonic epilepsy

Neurology ◽  
1996 ◽  
Vol 47 (4) ◽  
pp. 912-918 ◽  
Author(s):  
E. C. Wirrell ◽  
C. S. Camfield ◽  
P. R. Camfield ◽  
K. E. Gordon ◽  
J. M. Dooley
Keyword(s):  
Juvenile Myoclonic Epilepsy ◽  
Absence Epilepsy ◽  
Myoclonic Epilepsy ◽  
Childhood Absence Epilepsy ◽  
Long Term Prognosis

scholarly journals Long-term prognosis of juvenile myoclonic epilepsy: A systematic review searching for sex differences

Seizure ◽  
2021 ◽  
Vol 86 ◽  
pp. 41-48
Author(s):  
Loretta Giuliano ◽  
Greta Mainieri ◽  
Umberto Aguglia ◽  
Leonilda Bilo ◽  
Vania Durante ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sex Differences ◽  
Juvenile Myoclonic Epilepsy ◽  
Myoclonic Epilepsy ◽  
Long Term Prognosis

scholarly journals Juvenile myoclonic epilepsy subsyndromes: family studies and long-term follow-up

Brain ◽  
2006 ◽  
Vol 129 (5) ◽  
pp. 1269-1280 ◽  
Author(s):  
Iris E. Martínez-Juárez ◽  
María Elisa Alonso ◽  
Marco T. Medina ◽  
Reyna M. Durón ◽  
Julia N. Bailey ◽  
...  
Keyword(s):  
Family Studies ◽  
Juvenile Myoclonic Epilepsy ◽  
Myoclonic Epilepsy ◽  
Long Term Follow Up

scholarly journals The cause of death, risk factors and long-term prognosis of acute myocardial infarction.

1987 ◽  
Vol 51 (3) ◽  
pp. 332-337 ◽  
Author(s):  
MIKIO ARITA ◽  
YUJI UENO ◽  
OSAMU MOHARA ◽  
HIDEYA NAKAMURA ◽  
YOSHIAKI TOMOBUCHI ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cause Of Death ◽  
Death Risk ◽  
Long Term Prognosis

Characterization of Sepsis and Sepsis-Associated Encephalopathy

2017 ◽  
Vol 34 (11-12) ◽  
pp. 938-945 ◽  
Author(s):  
Qing Feng ◽  
Yu-Hang Ai ◽  
Hua Gong ◽  
Long Wu ◽  
Mei-Lin Ai ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Risk Factor ◽  
Diagnostic Criteria ◽  
Mortality Rates ◽  
Apache Ii ◽  
Apache Ii Score ◽  
Long Term Prognosis

Background: Sepsis and sepsis-associated encephalopathy (SAE) are common intensive care unit (ICU) diseases; the morbidity and mortality are high. The present study analyzed the sensitivity of different diagnostic criteria of sepsis 1.0 and 3.0, epidemiological characteristics of sepsis and SAE, and explored its risk factors for death, short-term, and long-term prognosis. Methods: The retrospective study included patients in ICU from January 2015 to June 2016. After excluding 58 patients, 175 were assigned to either an SAE or a non-SAE group (patients with sepsis but no encephalopathy). The sensitivity of the diagnostic criteria was compared between sepsis 1.0 and 3.0, respectively. Between-group differences in baseline data, Acute Physiology and Chronic Health Evaluation II score (APACHE II score), Sequential Organ Failure Assessment score (SOFA score), etiological data, biochemical indicators, and 28-day and 180-day mortality rates were analyzed. Survival outcomes and long-term prognosis were observed, and risk factors for death were analyzed through 180-day follow-up. Results: The sensitivity did not differ significantly between the diagnostic criteria of sepsis 1.0 and 3.0 ( P = .286). The 42.3% incidence of SAE presented a significantly high APACHE II and SOFA scores as well as 28-day mortality and 180-day mortality (all P < .001). The incidence of death was 37.1%. The multivariate stepwise regression analysis demonstrated that the risk of death in SAE group was significantly higher than the non-SAE group ( P < .001). Sepsis-associated encephalopathy is a risk factor for sepsis-related death (relative risk [RR] = 2.868; 95% confidence interval: 1.730-4.754; P < .001). Although males showed a significantly high rate of 28-day and 180-day mortality ( P = .035 and .045), it was not an independent risk factor for sepsis-related death ( P = .072). The long-term prognosis of patients with sepsis was poor with decreased quality of life. No significant difference was observed in prognosis between the SAE and non-SAE groups ( P > .05). Conclusion: Both diagnostic criteria cause misdiagnosis, and the sensitivity did not differ significantly. The incidence of SAE was high, and 28-day and 180-day mortality rates were significantly higher than those without SAE. Sepsis-associated encephalopathy is a risk factor for poor outcome. The overall long-term prognosis of patients with sepsis was poor, and the quality of life decreased.

scholarly journals Refractory juvenile myoclonic epilepsy: a meta‐analysis of prevalence and risk factors

2018 ◽  
Vol 26 (6) ◽  
pp. 856-864 ◽  
Author(s):  
R. Stevelink ◽  
B. P. C. Koeleman ◽  
J. W. Sander ◽  
F. E. Jansen ◽  
K. P. J. Braun
Keyword(s):  
Risk Factors ◽  
Meta Analysis ◽  
Juvenile Myoclonic Epilepsy ◽  
Myoclonic Epilepsy

scholarly journals Infective endocarditis at a tertiary care hospital in South Korea

Heart ◽  
2020 ◽  
Vol 107 (2) ◽  
pp. 135-141 ◽  
Author(s):  
Jung Ho Kim ◽  
Hi Jae Lee ◽  
Nam Su Ku ◽  
Seung Hyun Lee ◽  
Sak Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Infective Endocarditis ◽  
Mortality Rate ◽  
South Korea ◽  
Hospital Mortality ◽  
Care Hospital ◽  
Multivariable Logistic Regression ◽  
Long Term Prognosis

ObjectiveThe treatment of infective endocarditis (IE) has become more complex with the current myriad healthcare-associated factors and the regional differences in causative organisms. We aimed to investigate the overall trends, microbiological features, and outcomes of IE in South Korea.MethodsA 12-year retrospective cohort study was performed. Poisson regression was used to estimate the time trends of IE incidence and mortality rate. Risk factors for in-hospital mortality were identified with multivariable logistic regression, and model comparison was performed to evaluate the predictive performance of notable risk factors. Kaplan-Meier survival analysis and Cox regression were performed to assess long-term prognosis.ResultsWe included 419 patients with IE, the incidence of which showed an increasing trend (relative risk 1.06, p=0.005), whereas mortality demonstrated a decreasing trend (incidence rate ratio 0.93, p=0.020). The in-hospital mortality rate was 14.6%. On multivariable logistic regression analysis, aortic valve endocarditis (OR 3.18, p=0.001), IE caused by Staphylococcus aureus (OR 2.32, p=0.026), neurological complications (OR 1.98, p=0.031), high Sequential Organ Failure Assessment score (OR 1.22, p=0.023) and high Charlson Comorbidity Index (OR 1.11, p=0.019) were predictors of in-hospital mortality. Surgical intervention for IE was a protective factor against in-hospital mortality (OR 0.25, p<0.001) and was associated with improved long-term prognosis compared with medical treatment only (p<0.001).ConclusionsThe incidence of IE is increasing in South Korea. Although the mortality rate has slightly decreased, it remains high. Surgery has a protective effect with respect to both in-hospital mortality and long-term prognosis in patients with IE.

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