scholarly journals Diagnostic yield of capillary compared to venous glucose in the diagnosis of hypoglycorrhachia in children: A prospective, observational study

2021 ◽  
Vol 43 (1) ◽  
pp. 63-68
Author(s):  
Juan David Farfán-Albarracín ◽  
Cristina Lorena Ramírez-Sierra ◽  
Oscar Mauricio Espitia Segura ◽  
Sofy Helena Pérez ◽  
Hugo Andrés Téllez Prada ◽  
...  
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Diagnostic Yield ◽  
Venous Glucose

scholarly journals Bronchoscopy and fine needle aspiration cytology aided diagnosis of suspected lung malignancy- A prospective observational study

2018 ◽  
Vol 7 (4) ◽  
pp. 168-172
Author(s):  
Subash Pant ◽  
Sanjeet Krishna Shrestha ◽  
Lucky Sharma ◽  
Rinky Mahaseth ◽  
Arpana Neopane
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Diagnostic Yield ◽  
College Teaching ◽  
Needle Aspiration ◽  
Lung Lesion ◽  
Point Of View ◽  
Lung Lesions ◽  
Lung Malignancy ◽  
Endobronchial Growth

Background: Flexible bronchoscopy is the main modality of diagnosing lung malignancy as per the location of lesion in our setup. Accurate diagnosis and categorization into various types is vital for its prognostic and management point of view. Objectives: The study was conducted to find out yield of bronchoscopy and FNAC in suspected lung lesion and to know the various subtypes of bronchogenic carcinoma. Methodology: The study was conducted in Kathmandu Medical College Teaching Hospital from December 2016 to May 2018. This was a prospective observational study conducted in 90 radiological suspected lung lesions. Radiological, bronchoscopy, histopathological and cytopathological findings were analyzed and evaluated. Data were recorded on a pre-designed proforma and entered into Statistical Package for the Social Sciences version 20. Results: Among 90 suspected lung lesions who underwent contrast enhanced computed tomography, chest mass lesion was seen in 57(63.3%) subjects, nodular in 8 (8.9%), consolidation in 7 (7.8%), fibrosis in 7 (7.8%), collapse in 6 (6.7%) and pleural effusion in 3 (3. 3%).The most common malignancy was squamous cell carcinoma (53.48%). Lung malignancy was more common among endobronchial growth. The tendency of lesion to be malignant however tended to be significant at right upper lobe (p=0.02). When the suspected lesion was mass, the occurrence of malignancy was significantly higher (p<0.05). Conclusion: The diagnostic yield increases with presence of right upper lesion with endobronchial growth. When the lung lesion presents as mass, the yield of having malignancy is also higher.

Epidemiological, Clinical, and Microbiological Characteristics of Serotype-3 Streptoccocus pneumoniae Infection after a Partial Introduction of the 13-Valent Pneumococcal Conjugate Vaccine: A Prospective Observational Study

2020 ◽  
Vol 15 (04) ◽  
pp. 169-175
Author(s):  
Anna Solé-Ribalta ◽  
Maria F. de Sevilla ◽  
Fernando Moraga-Llop ◽  
Alvaro D. Conradi ◽  
Sergi Hernández ◽  
...  
Keyword(s):  
Observational Study ◽  
Real Time ◽  
Conjugate Vaccine ◽  
Invasive Pneumococcal Disease ◽  
Pneumococcal Conjugate Vaccine ◽  
Pneumococcal Disease ◽  
Prospective Observational Study ◽  
Diagnostic Yield ◽  
Positive Real ◽  
Microbiological Characteristics

Abstract Objective After the introduction of 13-valent pneumococcal conjugate vaccine (PCV13), a decrease of serotype-3 invasive pneumococcal disease (IPD) has not been homogenously observed around Europe. The aim of the study is to analyze the incidence of serotype-3 IPD in our area (Catalonia, Spain) and describe what microbiological and clinical characteristics distinguish serotype-3 IPD from nonserotype-3 IPD. Methods This study is a prospective observational study performed in three hospitals of Barcelona (Spain), from January 2012 to June 2016. Patients younger than 18 years with a diagnosis of IPD were included. Epidemiological, clinical, and microbiological data were collected. Results A total of 253 cases of IPD were included; of these, 53 were caused by serotype 3. The incidence rate of serotype-3 IPD remained stable over the study years (risk ratio [RR] = 0.64; 95% confidence interval [CI]: 0.3–1.38). In 92.5% (49/53) of the cases of serotype-3 IPD, the diagnosis was pneumonia and 89.8% (44/49) of them reported a complicated pneumonia. Also, 98.1% (52/53) were detected by positive real-time polymerase chain reaction (PCR) in blood or pleural effusion. Seventeen patients were properly vaccinated with PCV13 before the infection. Conclusion After the introduction of PCV13 a global decline of invasive pneumococcal disease has been reported, specially, due to a decrease of serotypes 1 and 19A cases. Serotype-3 Streptococcus pneumoniae IPD remained stable throughout the years of study, being currently the main serotype causing IPD in our area. Serotype 3 causes mostly pneumonia and physicians must be aware of possible complications. Real-time PCR have a significantly higher diagnostic yield for serotype 3 compared with culture. Some vaccination failures were observed.

Prospective Observational Study of Sleep and PTSD Symptoms in Patients Undergoing PTSD Treatment

2009 ◽  
Author(s):  
Ihori Kobayashi ◽  
Brian Hall ◽  
Courtney Hout ◽  
Vanessa Springston ◽  
Patrick Palmieri
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Ptsd Symptoms ◽  
Ptsd Treatment

The 1000Plus study protocol – a prospective observational study on the mismatch concept in a 3.0 T MRI

2009 ◽  
Vol 36 (S 02) ◽  
Author(s):  
B Hotter ◽  
S Pittl ◽  
M Ebinger ◽  
G Oepen ◽  
K Jegzentis ◽  
...  
Keyword(s):  
Observational Study ◽  
Study Protocol ◽  
Prospective Observational Study ◽  
3.0 T ◽  
3.0 T Mri
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