Vasculitis of the mesenteric circulation

Matthew J. Koster; Kenneth J. Warrington

doi:10.1016/j.bpg.2016.12.003

Predicting Perinatal Outcome from Prenatal Ultrasound Characteristics in Pregnancies Complicated by Gastroschisis

Fetal Diagnosis and Therapy ◽

10.1159/000440699 ◽

2015 ◽

Vol 39 (4) ◽

pp. 279-286 ◽

Cited By ~ 13

Author(s):

Gabriella Martillotti ◽

Isabelle Boucoiran ◽

Amélie Damphousse ◽

Andrée Grignon ◽

Eric Dubé ◽

...

Keyword(s):

Gestational Age ◽

Predictive Value ◽

Intrauterine Growth Restriction ◽

Adverse Outcome ◽

Prenatal Ultrasound ◽

Intestinal Lumen ◽

Third Trimester ◽

Mesenteric Circulation ◽

Intrauterine Growth ◽

Bowel Dilatation

Introduction: The objective of the study was to establish the predictive value of prenatal ultrasound markers for complex gastroschisis (GS) in the first 10 days of life. Material and Methods: In this retrospective cohort study over 11 years (2000-2011) of 117 GS cases, the following prenatal ultrasound signs were analyzed at the last second- and third-trimester ultrasounds: intrauterine growth restriction, intra-abdominal bowel dilatation (IABD) adjusted for gestational age, extra-abdominal bowel dilatation (EABD) ≥25 mm, stomach dilatation, stomach herniation, perturbed mesenteric circulation, absence of bowel lumen and echogenic dilated bowel loops (EDBL). Results: Among 114 live births, 16 newborns had complex GS (14.0%). Death was seen in 16 cases (13.7%): 3 intrauterine fetal deaths, 9 complex GS and 4 simple GS. Second-trimester markers had limited predictive value. Third-trimester IABD, EABD, EDBL, absence of intestinal lumen and perturbed mesenteric circulation were statistically associated with complex GS and death. IABD was able to predict complex GS with a sensitivity of 50%, a specificity of 91%, a positive predictive value of 47% and a negative predictive value of 92%. Discussion: Third-trimester IABD adjusted for gestational age appears to be the prenatal ultrasound marker most strongly associated with adverse outcome in GS.

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Efferent Function of Capsaicin-Sensitive Nerves and Neurogenic Vasodilation in Rat Mesenteric Circulation

Advances in Experimental Medicine and Biology - Sensory Nerves and Neuropeptides in Gastroenterology ◽

10.1007/978-1-4899-0744-8_22 ◽

1991 ◽

pp. 241-248

Author(s):

Stefano Manzini ◽

Manuela Tramontana ◽

Francesca Perretti

Keyword(s):

Mesenteric Circulation ◽

Efferent Function ◽

Neurogenic Vasodilation

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Vascular anomalies in the mesenteric circulation of patients with Crohn’s disease: a pilot study

Veins and Lymphatics ◽

10.4081/vl.2017.6817 ◽

2017 ◽

Vol 6 (2) ◽

Author(s):

Matilde Zamboni ◽

Maria Grazia Sibilla ◽

Roberto Galeotti ◽

Massimo Pedriali ◽

Simona Ascanelli

Keyword(s):

Crohn’S Disease ◽

Pilot Study ◽

Crohn's Disease ◽

Vascular System ◽

Current Treatment ◽

Small Sample ◽

Vascular Anomalies ◽

Chronic Inflammatory Bowel Disease ◽

Mesenteric Circulation ◽

Inflammatory Bowel

Crohn’s disease (CD) is a chronic inflammatory bowel disease and its pathogenesis is still not well understood. Previous studies suggested the possibility of the involvement of vascular system, but, todate, the mesenteric circulation has poor been investigated, especially in complicated CD cases requiring colectomy. We investigated the mesenteric circulation in a case-control pilot study, including 19 controls and 7 patients affected by complicated cases of CD. Cases and controls underwent selective angiography of both superior and inferior mesenteric district. Transit time was found either significantly shortened in 2/7 cases (29%), or prolonged 5/7 (71%) (P=0.0034 in the superior mesenteric district; P=0.0079 in the inferior mesenteric district), respectively due to the presence of A-V malformations and of a miscellaneous of venous abnormalities, which included thrombosis, hypoplasia and extra-truncular venous malformations. Our study demonstrates the presence of congenital or acquired vascular anomalies in a small sample of CD patients not responder to current treatment and with severe complications. The present pilot study warrants further investigations.

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