Artificial liver support devices as treatment option for liver failure

2012 ◽  
Vol 26 (1) ◽  
pp. 17-26 ◽  
Author(s):  
Frederik Nevens ◽  
Wim Laleman
Keyword(s):  
Liver Failure ◽  
Treatment Option ◽  
Artificial Liver ◽  
Liver Support ◽  
Artificial Liver Support ◽  
Liver Support Devices ◽  
Support Devices

ARTIFICIAL LIVER SUPPORT DEVICES FOR FULMINANT LIVER FAILURE

2001 ◽  
Vol 5 (2) ◽  
pp. 415-430 ◽  
Author(s):  
Anna Sechser ◽  
Joseph Osorio ◽  
Chris Freise ◽  
Robert W. Osorio
Keyword(s):  
Liver Failure ◽  
Artificial Liver ◽  
Fulminant Liver Failure ◽  
Liver Support ◽  
Artificial Liver Support ◽  
Liver Support Devices ◽  
Support Devices

Detoxification Capabilities of Adsorbents for Artificial Liver Support Devices: A Comparison

2014 ◽  
Vol 936 ◽  
pp. 789-794
Author(s):  
Wei Ping Ding ◽  
Li Li Zou ◽  
Ying Ying Pei ◽  
Si Jie Sun ◽  
Da Yong Gao
Keyword(s):  
Activated Carbon ◽  
Adsorption Rate ◽  
Artificial Liver ◽  
Order Kinetic ◽  
Liver Support ◽  
Artificial Liver Support ◽  
Anion Resin ◽  
Adsorption Technology ◽  
Liver Support Devices ◽  
Support Devices

Adsorption performances of activated carbon Norit RO 0.8, neutral resin Amberlite XAD-7, anion resin Dowex 1x4 and cation resin Dowex 50wx4 were investigated in detail for artificial liver support devices. Firstly, equilibrium adsorption experiments of these adsorbents to albumin, creatinine, bilirubin, tryptophan and cholic acid were conducted respectively. Then their adsorption capacities were obtained by curve fitting. The results indicate that activated carbon Norit RO 0.8 and anion resin Dowex 1x4 are two better adsorbents for removing toxins. Lastly, adsorption rate constants of activated carbon Norit RO 0.8 and anion resin Dowex 1x4 to all above solutes were studied with pseudo-first and second-order kinetic adsorption models. The results show that the toxin adsorption rate of anion resin Dowex 1x4 is faster than that of activated carbon Norit RO 0.8. The systematical experimental results in this paper are very important references for researchers in the field of blood purification based on adsorption technology.

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