Quantitative analysis of aggregation in dilute solutions of effectively rigid biomacromolecules via the combination of oscillatory flow birefringence and viscoelasticity measurements: example study of aggregation of bovine fibrinogen in aqueous glycerol, and detection of a large aggregate formed on addition of guanidine hydrochloride

2004 ◽  
Vol 112 (2-3) ◽  
pp. 155-163 ◽  
Author(s):  
J.W. Miller ◽  
F.H.M. Nestler ◽  
J.L. Schrag
Biorheology ◽  
1973 ◽  
Vol 10 (3) ◽  
pp. 351-360 ◽  
Author(s):  
George B. Thurston ◽  
Robert S. Wilkinson

1997 ◽  
Vol 30 (18) ◽  
pp. 5527-5540 ◽  
Author(s):  
Jacques Bossart ◽  
Hans Christian Öttinger

1944 ◽  
Vol 27 (3) ◽  
pp. 201-232 ◽  
Author(s):  
A. S. C. Lawrence ◽  
Joseph Needham ◽  
Shih-Chang Shen

1. A coaxial viscosimeter which permits the simultaneous determination of relative and anomalous viscosity and of flow-birefringence is described. Flow-anomaly and flow-birefringence are regarded as characteristic of elongated micelles and molecules. 2. Such methods have been applied to dilute solutions of proteins. The conditions under which the coaxial (Couette) viscosimeter measures the viscosity of the bulk phase and the surface film phase respectively have been investigated and are described. 3. The general behaviour of protein solutions subjected to shear is summarised.


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