scholarly journals TBS in early postmenopausal women with severe vertebral osteoporosis

Bone ◽  
2021 ◽  
Vol 142 ◽  
pp. 115698
Author(s):  
Jean-Michel Pouillès ◽  
Anna Gosset ◽  
Alice Breteau ◽  
Florence Anne Trémollieres
Author(s):  
Eleni Armeni ◽  
Areti Augoulea ◽  
Anastasia Palaiologou ◽  
Foteini Christidi ◽  
Anastasia Soureti ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e103444 ◽  
Author(s):  
Ruth Clapauch ◽  
André Felipe Mourão ◽  
Anete S. Mecenas ◽  
Priscila A. Maranhão ◽  
Ana Rossini ◽  
...  

Menopause ◽  
2021 ◽  
Vol 28 (11) ◽  
pp. 1214-1224
Author(s):  
Tine Vrist Dam ◽  
Line Barner Dalgaard ◽  
Christian Bejlegaard Thomsen ◽  
Rikke Hjortebjerg ◽  
Steffen Ringgaard ◽  
...  

2019 ◽  
Vol 105 (5) ◽  
pp. e2050-e2060 ◽  
Author(s):  
Jennifer L Gordon ◽  
David R Rubinow ◽  
Lana Watkins ◽  
Alan L Hinderliter ◽  
Melissa C Caughey ◽  
...  

Abstract Background The arterial effects of hormone therapy remain controversial. This study tested the effects of transdermal estradiol plus intermittent micronized progesterone (TE + IMP) in healthy perimenopausal and early postmenopausal women on several mechanisms involved in the pathophysiology of arterial disease. Methods Healthy perimenopausal and early postmenopausal women, ages 45 to 60 years, were enrolled in this randomized, double-blind, placebo-controlled trial. Women were randomized to receive TE (0.1 mg/day) + IMP (200 mg/day for 12 days) or identical placebo patches and pills for 12 months. Outcomes included: change in stress reactivity composite z-score (combining inflammatory, cortisol, and hemodynamic responses to a standardized psychological laboratory stressor); flow-mediated dilation (FMD) of the brachial artery (an index of vascular endothelial function); baroreflex sensitivity; and metabolic risk (presence of the metabolic syndrome or insulin resistance), all assessed at baseline and at months 6 and 12. Results Of 172 women enrolled, those assigned to TE + IMP tended to have higher resting baroreflex sensitivity than those assigned to placebo across the 6- and 12-month visits. Although treatment groups did not differ in terms of the other prespecified outcomes, a significant treatment-by-age interaction was found for FMD and stress reactivity such that an age-related decrease in FMD and increase in stress reactivity were seen among women assigned to placebo but not those assigned to TE + IMP. Women on TE + IMP also had lower resting diastolic blood pressure, lower levels of low-density lipoprotein cholesterol, and higher baroreflex sensitivity during stress testing. Conclusions TE + IMP tended to improve cardiac autonomic control and prevented age-related changes in stress reactivity and endothelial function among healthy perimenopausal and early postmenopausal women.


Sign in / Sign up

Export Citation Format

Share Document