A multiscale study of structural and compositional changes in a natural nanocomposite: Osteoporotic bone with chronic endogenous steroid excess

Bone ◽  
2021 ◽  
Vol 143 ◽  
pp. 115666
Author(s):  
Li Xi ◽  
Yi Zhang ◽  
Himadri Gupta ◽  
Nick Terrill ◽  
Pan Wang ◽  
...  
Author(s):  
D.C. Dufner

The general goal of this research is to clarify mechanisms of solid state reactions at the atomic level as a step in the rationalization of macroscopic reaction behavior in solids. A study of intermetallic alloy formation resulting from interdiffusion of metals in thin films can be made by HREM. In this work, reactions between Pt and Sn in thin films are studied to elucidate mechanisms for structural and compositional changes during the interdiffusion process.Thin films of Pt and Sn used in this study were prepared by the two-film method introduced by Shiojiri. Few hundred angstroms of Pt were vacuum-deposited onto holey carbon films mounted on TEM grids. Sn films with an average thickness of 200Å were created by evaporation at rates of 15-30 Å/sec onto air-cleaved KBr substrates. The Sn films were wet-stripped and collected on the holey Pt grids. Figure 1 shows a cross-section schematic of a Pt-Sn couple. While this two-film arrangement did not allow observations of the actual reaction interface, microtomy was used to produce cross-sections.


2016 ◽  
Author(s):  
Scheidt Annika vom ◽  
Matthias Krause ◽  
Klaus Puschel ◽  
Michael Amling ◽  
Bjorn Busse

GYNECOLOGY ◽  
2019 ◽  
Vol 21 (2) ◽  
pp. 76-79
Author(s):  
Anastasia G Syrkasheva ◽  
Yana A Petrosyan ◽  
Natalia V Dolgushina

Background. Luteal phase (LP) drug support is an important step in assisted reproductive technology (ART) programs efficacy. Aim. To present up-to-date data on an efficacy of LP hormonal support during ART cycles as well as to conduct a comparative analysis of various gestagen drug effectiveness. Materials and methods. To write this review domestic and foreign publications were searched in Russian and international search systems (PubMed, eLibrary, etc.) for the last 8 years. The review includs articles from peer-reviewed literature. Results. LP drug support becomes an essential step in infertility treatment in various ART programs. Although human chorionic gonadotropin drug injections in the posttransfer period leads to an activation of endogenous steroid hormones synthesis, exogenous hormones use is currently preferred because of not having a risk of ovarian hyperstimulation syndrome. Conclusions. The variety of progesterone drugs is accompanied by a lack of algorithms for their use in various clinical situations. Further studies are required to evaluate progesterone drugs efficacy for various subgroups of patients.


2002 ◽  
Vol 202 (3-4) ◽  
pp. 183-198 ◽  
Author(s):  
C.C Surdu-Bob ◽  
J.L Sullivan ◽  
S.O Saied ◽  
R Layberry ◽  
M Aflori

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