High bone mineral density in sickle cell disease: Prevalence and characteristics

Bone ◽  
2018 ◽  
Vol 110 ◽  
pp. 199-203 ◽  
Author(s):  
Gonzalo De Luna ◽  
Brigitte Ranque ◽  
Marie Courbebaisse ◽  
Jean-Antoine Ribeil ◽  
Djamal Khimoud ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Bone Mineral ◽  
Disease Prevalence ◽  
High Bone Mineral Density ◽  
Cell Disease ◽  
Mineral Density ◽  
High Bone

Bone Mineral Density in Sickle Cell Disease Patients

2014 ◽  
Vol 65 (1-3) ◽  
pp. 151-160
Author(s):  
Galila M. Mokhtar ◽  
Azza A. Tantawy ◽  
Ahmed E. Hamed ◽  
Amira A. Adly ◽  
Eman A. Ismail ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Bone Mineral ◽  
Cell Disease ◽  
Mineral Density

Evaluation of bone mineral density in children with sickle cell disease

2015 ◽  
Vol 82 (4) ◽  
pp. 216-221
Author(s):  
C. Garrido Colino ◽  
C. Beléndez Bieler ◽  
M. Pérez Díaz ◽  
E. Cela de Julián
Keyword(s):  
Bone Mineral Density ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Bone Mineral ◽  
Cell Disease ◽  
Mineral Density

Analysis of Calcium Profile and Bone Mineral Density in Patients with Sickle Cell Disease

Blood ◽  
2010 ◽  
Vol 116 (21) ◽  
pp. 4810-4810
Author(s):  
Lucila Macedo Gonçalves ◽  
Rodolfo Cancado ◽  
Tarissa Beatrice Zanata Petry ◽  
Murilo Rezende Melo ◽  
João Eduardo Salles ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Bone Mineral ◽  
Conflicts Of Interest ◽  
Genetic Disorder ◽  
Urinary Calcium ◽  
Cell Disease ◽  
Mineral Density ◽  
Subsequent Increase

Abstract Abstract 4810 Introduction: Sickle Cell Disease (SCD) is a genetic disorder where the red blood cells assume an abnormal, rigid, sickle shape, causing tissue hypoxia with subsequent increase of osteoclastic activity, originating osteopenia and osteoporosis. The prevalence of the osteoporosis in the SCD can vary from 25 a 50%, affecting more commonly the children. There are few data regarding the prevalence of bone mineral low density in adults. Our objective was to analyse the calcium profile and bone mineral density (BMD) of pacients with SCD and describe the prevalence of osteopenia in this group. Material and Methods: We have studied 49 patients with SCD analysing the serum and 24 hours urinary calcium, serum ferritin, LDH, parathyroid hormone (PTH) and BMD in the lombar vertebrae and proximal femoral. Results: From the 49 patients, 21(42.9%) were males and 28(57.1%) females, mean age of 27 years old (16-51 yr), 55.1% (27) of the patients presented osteopenia and 26.5% (13) osteoporosis, considering lombar vertebrae BMD. Only 18.4% (9) had normal BMD. Mean ± DP PTH was 85.3 ± 79.32 and mean ± DP serum calcium of 8.9 ± 0.44. Mean ± DP LDH was 970.8 ± 492.36 and we have observed significant correlation between this variable and low BMD (p<0.02). Conclusion: The prevalence of osteopenia and osteoporosis was extremely high (81.6%) in the studied patitents. The secondary hyperparatireoidism was present in many patients and we did not find hypoparathyroidism. The hemolysis appears as a factor that contributes for the low BMD. Disclosures: No relevant conflicts of interest to declare.

Klotho Level as a Marker of Low Bone Mineral Density in Egyptian Sickle Cell Disease Patients

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Mona Hamdy ◽  
Iman Shaheen ◽  
Hadeel Seif El Din ◽  
Basma Ali ◽  
Omnia Abdel Dayem
Keyword(s):  
Bone Mineral Density ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Bone Mineral ◽  
Cell Disease ◽  
Mineral Density ◽  
Low Bone Mineral Density

A pilot study of hormonal contraceptive use and bone mineral density in young women with sickle cell disease

2018 ◽  
Vol 65 (12) ◽  
pp. e27398
Author(s):  
Kristina J. Harrell ◽  
Joseph Stanek ◽  
Andrea E. Bonny ◽  
Myra Christian-Rancy ◽  
Susan E. Creary ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Pilot Study ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Bone Mineral ◽  
Young Women ◽  
Contraceptive Use ◽  
Hormonal Contraceptive ◽  
Cell Disease ◽  
Mineral Density

High prevalence and correlates of low bone mineral density in young adults with sickle cell disease

2006 ◽  
Vol 81 (4) ◽  
pp. 236-241 ◽  
Author(s):  
Redonda G. Miller ◽  
Jodi B. Segal ◽  
Bimal H. Ashar ◽  
Sophia Leung ◽  
Shamim Ahmed ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Young Adults ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Bone Mineral ◽  
Cell Disease ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
High Prevalence
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