Osteomalacia induced by long-term low-dose adefovir dipivoxil: Clinical characteristics and genetic predictors

Bone ◽  
2016 ◽  
Vol 93 ◽  
pp. 97-103 ◽  
Author(s):  
Zhe Wei ◽  
Jin-wei He ◽  
Wen-zhen Fu ◽  
Zhen-lin Zhang
Keyword(s):  
Clinical Characteristics ◽  
Adefovir Dipivoxil ◽  
Low Dose ◽  
Genetic Predictors

Low-dose adefovir dipivoxil may induce Fanconi syndrome: clinical characteristics and long-term follow-up for Chinese patients

2015 ◽  
Vol 20 (6) ◽  
pp. 603-611 ◽  
Author(s):  
Li-Jun Xu ◽  
Yan Jiang ◽  
Ruo-Xi Liao ◽  
Hua-Bing Zhang ◽  
Jiang-Feng Mao ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Adefovir Dipivoxil ◽  
Fanconi Syndrome ◽  
Low Dose ◽  
Chinese Patients ◽  
Long Term Follow Up

scholarly journals Osteomalacia and renal failure due to Fanconi syndrome caused by long-term low-dose Adefovir Dipivoxil: a case report

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Qian Xiang ◽  
Zhiyan Liu ◽  
Yanyan Yu ◽  
Hanxu Zhang ◽  
Qiufen Xie ◽  
...  
Keyword(s):  
Renal Failure ◽  
Case Report ◽  
Adefovir Dipivoxil ◽  
Fanconi Syndrome ◽  
Low Dose

Osteomalacia and Fanconi's syndrome caused by long-term low-dose adefovir dipivoxil

2015 ◽  
Vol 40 (3) ◽  
pp. 345-348 ◽  
Author(s):  
B.-F. Wang ◽  
Y. Wang ◽  
B.-Y. Wang ◽  
F.-R. Sun ◽  
D. Zhang ◽  
...  
Keyword(s):  
Adefovir Dipivoxil ◽  
Low Dose ◽  
Fanconi’S Syndrome ◽  
Fanconi's Syndrome

Osteomalacia due to Fanconi’s syndrome and renal failure caused by long-term low-dose adefovir dipivoxil

2012 ◽  
Vol 17 (1) ◽  
pp. 147-148 ◽  
Author(s):  
Homare Shimohata ◽  
Shinsuke Sakai ◽  
Yujiro Ogawa ◽  
Kouichi Hirayama ◽  
Masaki Kobayashi
Keyword(s):  
Renal Failure ◽  
Adefovir Dipivoxil ◽  
Low Dose ◽  
Fanconi’S Syndrome ◽  
Fanconi's Syndrome

scholarly journals Clinical features of hypophosphatemic osteomalacia induced by long-term low-dose adefovir dipivoxil

2017 ◽  
Vol Volume 12 ◽  
pp. 41-45 ◽  
Author(s):  
Sheng Zhu ◽  
Yu-Hui Yang ◽  
Rong-Wei Gao ◽  
Ran Li ◽  
Yu-Zhen Zou ◽  
...  
Keyword(s):  
Clinical Features ◽  
Adefovir Dipivoxil ◽  
Low Dose ◽  
Hypophosphatemic Osteomalacia

Ovarian Dysfunction in Fetally Irradiated Beagles

1977 ◽  
Vol 35 ◽  
pp. 658-659
Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Long Term Effects ◽  
Ovarian Dysfunction ◽  
Dose Rates ◽  
Highly Sensitive ◽  
Microscopic Evaluation ◽  
Ovarian Pathology ◽  
Normal Offspring

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.

The Acute Effect of Alcohol on Various Memory Processes

2010 ◽  
Vol 24 (4) ◽  
pp. 249-252 ◽  
Author(s):  
Márk Molnár ◽  
Roland Boha ◽  
Balázs Czigler ◽  
Zsófia Anna Gaál
Keyword(s):  
Low Dose ◽  
Short Term Memory ◽  
Acute Effect ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Processes ◽  
Different Types ◽  
The Brain ◽  
Legal Consequences

This review surveys relevant and recent data of the pertinent literature regarding the acute effect of alcohol on various kinds of memory processes with special emphasis on working memory. The characteristics of different types of long-term memory (LTM) and short-term memory (STM) processes are summarized with an attempt to relate these to various structures in the brain. LTM is typically impaired by chronic alcohol intake but according to some data a single dose of ethanol may have long lasting effects if administered at a critically important age. The most commonly seen deleterious acute effect of alcohol to STM appears following large doses of ethanol in conditions of “binge drinking” causing the “blackout” phenomenon. However, with the application of various techniques and well-structured behavioral paradigms it is possible to detect, albeit occasionally, subtle changes of cognitive processes even as a result of a low dose of alcohol. These data may be important for the consideration of legal consequences of low-dose ethanol intake in conditions such as driving, etc.

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