Minodronic acid ameliorates vertebral bone strength by increasing bone mineral density in 9-month treatment of ovariectomized cynomolgus monkeys

Bone ◽  
2016 ◽  
Vol 88 ◽  
pp. 157-164 ◽  
Author(s):  
Makoto Tanaka ◽  
Hiroshi Mori ◽  
Kazuhito Kawabata ◽  
Tasuku Mashiba
Keyword(s):  
Bone Mineral Density ◽  
Bone Strength ◽  
Bone Mineral ◽  
Mineral Density ◽  
Cynomolgus Monkeys ◽  
Vertebral Bone ◽  
Minodronic Acid

Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength

2010 ◽  
Vol 25 (5) ◽  
pp. 948-959 ◽  
Author(s):  
Michael S Ominsky ◽  
Fay Vlasseros ◽  
Jacquelin Jolette ◽  
Susan Y Smith ◽  
Brian Stouch ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Formation ◽  
Bone Strength ◽  
Bone Mineral ◽  
Mineral Density ◽  
Cynomolgus Monkeys ◽  
Sclerostin Antibody

Influence of electro-acupuncture on bone mineral density, bone strength and ultrastructure in ovariectomized rats

Bone ◽  
2006 ◽  
Vol 38 (3) ◽  
pp. 27-28 ◽  
Author(s):  
Z.G. Luo ◽  
A.T. Wang ◽  
W.S. Yu ◽  
Y. Zhao ◽  
P. Hu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Strength ◽  
Bone Mineral ◽  
Ovariectomized Rats ◽  
Mineral Density

Vertebral bone mineral density of the elderly in the urban community by mobile DXA

1994 ◽  
Vol 12 (1) ◽  
pp. 9-16 ◽  
Author(s):  
Takao Suzuki ◽  
Hiroshi Haga ◽  
Seiji Yasumura ◽  
Harumi Nagai ◽  
Hidenori Amano ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Urban Community ◽  
The Elderly ◽  
Mineral Density ◽  
Vertebral Bone ◽  
Vertebral Bone Mineral Density

475 A Novel Means of Assessing Bone Mineral Density and Bone Strength in Patients With Inflammatory Bowel Disease Undergoing CT Enterography

2013 ◽  
Vol 144 (5) ◽  
pp. S-86
Author(s):  
Nicholas K. Weber ◽  
Jeff L. Fidler ◽  
Bart L. Clarke ◽  
Sundeep Khosla ◽  
Joel G. Fletcher ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Inflammatory Bowel Disease ◽  
Bone Strength ◽  
Bone Mineral ◽  
Bowel Disease ◽  
Ct Enterography ◽  
Mineral Density ◽  
Inflammatory Bowel

scholarly journals Beyond Bone Mineral Density: A New Dual X-Ray Absorptiometry Index of Bone Strength to Predict Fragility Fractures, the Bone Strain Index

2021 ◽  
Vol 7 ◽  
Author(s):  
Fabio Massimo Ulivieri ◽  
Luca Rinaudo
Keyword(s):  
Bone Mineral Density ◽  
Density Distribution ◽  
Bone Strength ◽  
Bone Quality ◽  
Bone Mineral ◽  
Fragility Fracture ◽  
Bone Strain ◽  
Mineral Density ◽  
Strain Index ◽  
X Ray

For a proper assessment of osteoporotic fragility fracture prediction, all aspects regarding bone mineral density, bone texture, geometry and information about strength are necessary, particularly in endocrinological and rheumatological diseases, where bone quality impairment is relevant. Data regarding bone quantity (density) and, partially, bone quality (structure and geometry) are obtained by the gold standard method of dual X-ray absorptiometry (DXA). Data about bone strength are not yet readily available. To evaluate bone resistance to strain, a new DXA-derived index based on the Finite Element Analysis (FEA) of a greyscale of density distribution measured on spine and femoral scan, namely Bone Strain Index (BSI), has recently been developed. Bone Strain Index includes local information on density distribution, bone geometry and loadings and it differs from bone mineral density (BMD) and other variables of bone quality like trabecular bone score (TBS), which are all based on the quantification of bone mass and distribution averaged over the scanned region. This state of the art review illustrates the methodology of BSI calculation, the findings of its in reproducibility and the preliminary data about its capability to predict fragility fracture and to monitor the follow up of the pharmacological treatment for osteoporosis.

scholarly journals Effect of minodronic acid (ONO-5920) on bone mineral density and arthritis in adult rats with collagen-induced arthritis

2003 ◽  
Vol 48 (6) ◽  
pp. 1732-1741 ◽  
Author(s):  
Itsuro Yamane ◽  
Hiroshi Hagino ◽  
Toru Okano ◽  
Makoto Enokida ◽  
Daisuke Yamasaki ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Collagen Induced Arthritis ◽  
Adult Rats ◽  
Minodronic Acid
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