scholarly journals Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American—Diabetes Heart Study

Bone ◽  
2016 ◽  
Vol 87 ◽  
pp. 71-77 ◽  
Author(s):  
Nicholette D. Palmer ◽  
Jasmin Divers ◽  
Lingyi Lu ◽  
Thomas C. Register ◽  
J. Jeffrey Carr ◽  
...  
Keyword(s):  
Vitamin D ◽  
African American ◽  
Parathyroid Hormone ◽  
Serum Vitamin ◽  
Admixture Mapping ◽  
Serum Vitamin D ◽  
Heart Study ◽  
Diabetes Heart Study

scholarly journals Thecomparisonofserumbiomarkersin patients with osteoarthritisand rheumatoidarthritis

2018 ◽  
Vol 6 (2) ◽  
pp. 1-11
Author(s):  
Almandlawi S G ◽  
Ahmed A S
Keyword(s):  
Rheumatoid Arthritis ◽  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Parathyroid Hormone ◽  
Calcium Phosphate ◽  
Serum Vitamin ◽  
Type Ii Collagen ◽  
Healthy Controls ◽  
Type Ii ◽  
Serum Vitamin D

Introduction: This study aims to assess the status of serum vitamin D, parathyroid hormone, type II collagen, calcium, phosphate,albumin, and alkaline phosphatase in osteoarthritis and rheumatoidarthritis patients and to study their association with rheumatoid arthritis disease activity. Materials and Methods: This prospectivecross-sectional study was conducted at the clinical analysis department, College of Pharmacy, Hawler Medical University in 2017.They study samples were collected at Rizgary Teaching Hospitalduring the period September 2015 to January 2016. A total of(N=156) participants were included: (N=53) patients with rheumatoid arthritis (RA), (N=53) with osteoarthritis (OA), and (N=50)healthy controls. Enzyme Linked Immuno Sorbent Assay kits determined serum vitamin D, parathyroid hormone, and type II collagen; and serum albumin, calcium, phosphate and alkaline phosphatase, were determined by standard colorimetric methods. Resultsand Discussion: Statistically significant higher levels of parathyroid hormone and type II collagen, with lower levels of Vitamin D,were found in the osteoarthritis group than the rheumatoid arthritisgroup and the healthy controls (P=0.007, P<0.001, P= 0.005) respectively. Multiple linear regression showed a statistically significant difference in serum type II collagen as a dependent variable, inpatients suffering from RA or OA compared to the healthy controlgroup; after adjusting for the effect of other independent studyvariables, there was a mean increase of (45.90 nmol/L, P<0.001)in RA patients, and OA patients showed greater levels of type IIcollagen (73.950 nmol/L) than the health control group (P<0.001).Conclusions: Elevated type II collagen levels, in conjunction witha low vitamin D status, may be strong discriminator between osteoarthritis and rheumatoid arthritis patients.

scholarly journals Relationship between Parathyroid Hormone Level and Early Remodeling Heart Failure after Acute Myocardial Infarction

2020 ◽  
Author(s):  
Zohreh Firouzi ◽  
Saeideh Mahdizadeh Sajjadieh ◽  
Saeideh Mahdizadeh Sajjadieh ◽  
Maryam Mousavi ◽  
Zahra Erfanian ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Acute Myocardial Infarction ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Serum Vitamin ◽  
Current Evidence ◽  
Serum Vitamin D ◽  
Serum Pth ◽  
Pth Level

Background: Previous studies have indicated that parathyroid hormone (PTH) has been linked to post-myocardial infarction (MI) development. The aim of this cross-sectional study was to evaluate the relationship between PTH level and heart failure due to post infarction remodeling during the first 72 hours of hospitalization. Methods: Seventy patients with a diagnosis of acute MI (age ≥18 years, 22 females and 48 males) were enrolled. Patients were admitted to the Imam Raza Educational, Research and Treatment Center, Mashhad University of Medical Sciences, Iran between July 2014 to September 2015. We measured PTH and vitamin D level. Blood samples were taken after 24 hours and 72 hours. Results: During the first 72 hours, the PTH level significantly increased in patients with Post-MI heart failure. 68% of the subjects had an inappropriate vitamin D level at the time of admission. Mean levels of vitamin D and PTH increased compared with the baselines (95% CI, 0.15 to 10.03, P: 0.044), (95% CI, 6.5 to 24.8, P:0.001) respectively. Conclusion: Acute elevations of serum PTH levels increased early remodeling heart failure after MI. Serum vitamin D status was independent of high serum PTH level. Based on the current evidence, PTH excess may be a risk factor for heart failure, so early treatment and omitting risk factors are the most effective strategies for the patients with acute myocardial infarction. J Pharm Care 2020; 8(1): 11-15.

Seasonal Periodicity of Serum Vitamin D and Parathyroid Hormone, Bone Resorption, and Fractures: The Geelong Osteoporosis Study

2004 ◽  
Vol 19 (5) ◽  
pp. 752-758 ◽  
Author(s):  
Julie A Pasco ◽  
Margaret J Henry ◽  
Mark A Kotowicz ◽  
Kerrie M Sanders ◽  
Ego Seeman ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Bone Resorption ◽  
Serum Vitamin ◽  
Seasonal Periodicity ◽  
Serum Vitamin D ◽  
Geelong Osteoporosis Study

scholarly journals Association of serum vitamin D and parathyroid hormone with subclinical atherosclerotic phenotypes: The Dong-gu Study

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0186421 ◽  
Author(s):  
Young-Hoon Lee ◽  
Sun-Seog Kweon ◽  
Jin-Su Choi ◽  
Hae-Sung Nam ◽  
Kyeong-Soo Park ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Serum Vitamin ◽  
Serum Vitamin D

scholarly journals Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study

2016 ◽  
Vol 51 (2) ◽  
pp. 451-461 ◽  
Author(s):  
Ioannis Karakis ◽  
Matthew P. Pase ◽  
Alexa Beiser ◽  
Sarah L. Booth ◽  
Paul F. Jacques ◽  
...  
Keyword(s):  
Vitamin D ◽  
Framingham Heart Study ◽  
Brain Aging ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Incident Dementia ◽  
Heart Study
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