scholarly journals Ethnic and geographic variations in the epidemiology of childhood fractures in the United Kingdom

Bone ◽  
2016 ◽  
Vol 85 ◽  
pp. 9-14 ◽  
Author(s):  
Rebecca J. Moon ◽  
Nicholas C. Harvey ◽  
Elizabeth M. Curtis ◽  
Frank de Vries ◽  
Tjeerd van Staa ◽  
...  
2018 ◽  
Vol 84 (8) ◽  
pp. e02590-17 ◽  
Author(s):  
Geng Zou ◽  
Jianwei Zhou ◽  
Ran Xiao ◽  
Liangsheng Zhang ◽  
Yuting Cheng ◽  
...  

ABSTRACTStreptococcus suis, a global zoonosis of pigs, shows regional differences in the prevalence of human-associated disease for Asian and non-Asian countries. The isolation rates and diversities ofS. suison tonsils of healthy slaughter pigs in China and the United Kingdom were studied for effects of geography, temperature, pig age, and farm type. Isolates underwent analysis of molecular serotype and multilocus sequence type and virulence-associated genotyping. Although we found no significant difference in positive isolation rates between Chinese and UK farms, the prevalences of serotypes previously associated with human disease were significantly greater in the Chinese collection (P= 0.003). A significant effect of temperature was found on the positive isolation rate of the Chinese samples and the prevalence of human disease-associated serotypes in the UKS. suispopulation (China,P= 0.004; United Kingdom,P= 0.024) and on the prevalence of isolates carrying key virulence genes in China (P= 0.044). Finally, we found marked diversity amongS. suisisolates, with statistically significant temperature effects on detection of multiple strain types within individual pigs. This study highlighted the high carriage prevalence and diversity ofS. suisamong clinically healthy pig herds of China and the United Kingdom. The significant effect of temperature on prevalence of isolation, human disease-associated serotypes, and diversity carried by individual pigs may shed new light on geographic variations in humanS. suis-associated disease.IMPORTANCEStreptococcus suisis a global zoonotic pathogen and also a normal colonizer mainly carried on the tonsil of pigs. Thus, it is important to study the effect of environmental and management-associated factors on theS. suispopulations in clinically healthy pigs. In this research, we investigated the similarities and differences between theS. suispopulations obtained from different pig ages, seasons, and farm management systems and discovered the relationship between high climatic temperature and the prevalence ofS. suis.


2009 ◽  
pp. 1-6 ◽  
Author(s):  
Nishan Fernando ◽  
Gordon Prescott ◽  
Jennifer Cleland ◽  
Kathryn Greaves ◽  
Hamish McKenzie

1990 ◽  
Vol 35 (8) ◽  
pp. 800-801
Author(s):  
Michael F. Pogue-Geile

1992 ◽  
Vol 37 (10) ◽  
pp. 1076-1077
Author(s):  
Barbara A. Gutek

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