Metabolic syndrome and the risk of bone fractures: A Meta-analysis of prospective cohort studies

Bone ◽  
2016 ◽  
Vol 84 ◽  
pp. 52-56 ◽  
Author(s):  
Libo Yang ◽  
Xiaohong Lv ◽  
Dailin Wei ◽  
Feng Yue ◽  
Jinying Guo ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Bone Fractures ◽  
Meta Analysis ◽  
Prospective Cohort Studies

scholarly journals Associations of Whole Grain and Refined Grain Consumption With Metabolic Syndrome. A Meta-Analysis of Observational Studies

2021 ◽  
Vol 8 ◽  
Author(s):  
Hongbin Guo ◽  
Jun Ding ◽  
Jieyu Liang ◽  
Yi Zhang
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Observational Studies ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Whole Grain ◽  
Cross Sectional ◽  
Prospective Cohort Studies ◽  
Embase Database

Background: The associations of whole grain and refined grain consumption with metabolic syndrome (MetS) has been evaluated in several epidemiological studies with conflicting results. This meta-analysis was therefore employed to further investigate the above associations.Method: We searched the PubMed, Web of Science and Embase database until March 2021 (without restriction for inclusion time), for observational studies on the associations of whole grain and refined grain consumption with MetS. The pooled relative risk (RR) of MetS for the highest vs. lowest category of whole grain and refined grain consumption, as well as their corresponding 95% confidence interval (CI) were calculated.Results: A total of 14 observational studies, which involved seven cross-sectional and seven prospective cohort studies, were identified. Specifically, nine studies were related to whole grain consumption, and the overall multi-variable adjusted RR demonstrated that the whole grain consumption was inversely associated with MetS (RR = 0.80, 95%CI: 0.67–0.97; P = 0.021). With regard to refined grain consumption, 13 studies were included. The overall multi-variable adjusted RR indicated that refined grain consumption was positively associated with MetS (RR = 1.37, 95%CI: 1.02–1.84; P = 0.036).Conclusions: The existing evidence suggests that whole grain consumption is negatively associated with MetS, whereas refined grain consumption is positively associated with MetS. Our result might be helpful to better consider the diet effect on MetS. However, more well-designed prospective cohort studies are needed to elaborate the concerned issues further.

scholarly journals Metabolic syndrome and the incidence of knee osteoarthritis: A meta-analysis of prospective cohort studies

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243576
Author(s):  
Daqing Nie ◽  
Guixin Yan ◽  
Wenyu Zhou ◽  
Zhengyi Wang ◽  
Guimei Yu ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Risk Factor ◽  
General Population ◽  
Knee Osteoarthritis ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Independent Risk Factor ◽  
Meta Analysis ◽  
Prospective Cohort Studies ◽  
Increased Risk

Background Cross-sectional studies suggest an association between metabolic syndrome (MetS) and knee osteoarthritis (KOA). We performed a meta-analysis to evaluate whether MetS is an independent risk factor for KOA. Methods Prospective cohort studies evaluating the association between MetS and KOA in general population were retrieved from PubMed and Embase. Only studies with multivariate analyses were included. Data were pooled with a random-effect model, which is considered to incorporate heterogeneity among the included studies. Results Five studies including 94,965 participants were included, with 18,990 people with MetS (20.0%). With a mean follow-up duration of 14.5 years, 2,447 KOA cases occurred. Pooled results showed that MetS was not significant associated with an increased risk of KOA after controlling of factors including body mass index (adjusted risk ratio [RR]: 1.06, 95% CI: 0.92~1.23, p = 0.40; I2 = 33%). Subgroup analysis showed that MetS was independently associated with an increased risk of severe KOA that needed total knee arthroplasty (RR = 1.16, 95% CI: 1.03~1.30, p = 0.02), but not total symptomatic KOA (RR = 0.84, 95% CI: 0.65~1.08, p = 0.18). Stratified analyses suggested that MetS was independently associated with an increased risk of KOA in women (RR = 1.23, 95% CI: 1.03~1.47, p = 0.02), but not in men (RR = 0.90, 95% CI: 0.70~1.14, p = 0.37). Conclusions Current evidence from prospective cohort studies did not support MetS was an independent risk factor of overall KOA in general population. However, MetS may be associated with an increased risk of severe KOA in general population, or overall KOA risk in women.

Metabolic syndrome and stroke: A meta-analysis of prospective cohort studies

2017 ◽  
Vol 40 ◽  
pp. 34-38 ◽  
Author(s):  
Xuelong Li ◽  
Xianliang Li ◽  
Hualiang Lin ◽  
Xian Fu ◽  
Wanrong Lin ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Prospective Cohort Studies

scholarly journals Association of Red Meat and Poultry Consumption With the Risk of Metabolic Syndrome: A Meta-Analysis of Prospective Cohort Studies

2021 ◽  
Vol 8 ◽  
Author(s):  
Hongbin Guo ◽  
Jun Ding ◽  
Jieyu Liang ◽  
Yi Zhang
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Lower Risk ◽  
Meta Analysis ◽  
Meat Consumption ◽  
Red Meat ◽  
Current Evidence ◽  
Prospective Cohort Studies ◽  
Randomized Controlled

Objective: This study aims to investigate the association of red meat (processed and unprocessed) and poultry consumption with the risk of metabolic syndrome (MetS).Methods: Prospective cohort studies on the association of red meat (processed and unprocessed) and poultry consumption with the risk of MetS were identified by comprehensive literature search in the PubMed, Web of Science, and Embase databases up to March 2021. The pooled relative risk (RR) of MetS with 95% CIs for the highest vs. lowest category of red meat or poultry consumption was extracted for meta-analysis.Results: A total of nine prospective cohort studies were included in this study. Among them, eight studies were identified for red meat consumption. The overall multi-variable adjusted RR demonstrated that red meat consumption was associated with a higher risk of MetS (RR = 1.35, 95% CI: 1.13–1.62; P = 0.001). Moreover, four and three studies were specifically related to processed and unprocessed red meat consumption, respectively. Both processed (RR = 1.48, 95% CI: 1.11–1.97; P = 0.007) and unprocessed red meat (RR = 1.32, 95% CI: 1.14–1.54; P = 0.0003) consumption was associated with a higher risk of MetS. With regard to poultry consumption, three studies were included. The overall multi-variable adjusted RR suggested that poultry consumption was associated with lower risk of MetS (RR = 0.85, 95% CI: 0.75–0.97; P = 0.02).Conclusions: The current evidence indicates that red meat (processed and unprocessed) consumption is associated with a higher risk of MetS, whereas, poultry consumption is associated with a lower risk of MetS. More well-designed randomized controlled trials are still needed to address the issues further.

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