Sclerostin antibody increased modeling-based bone formation and decreased bone resorption on endocortical surfaces in male cynomolgus monkeys

Bone ◽  
2012 ◽  
Vol 50 ◽  
pp. S34 ◽  
Author(s):  
M.S. Ominsky⁎ ◽  
Q.-T. Niu ◽  
H.Z. Ke
Keyword(s):  
Bone Resorption ◽  
Bone Formation ◽  
Cynomolgus Monkeys ◽  
Sclerostin Antibody

Sclerostin antibody increases bone mass by stimulating bone formation and inhibiting bone resorption in a hindlimb-immobilization rat model

Bone ◽  
2011 ◽  
Vol 48 (2) ◽  
pp. 197-201 ◽  
Author(s):  
XiaoYan Tian ◽  
Webster S.S. Jee ◽  
Xiaodong Li ◽  
Chris Paszty ◽  
Hua Zhu Ke
Keyword(s):  
Bone Resorption ◽  
Bone Formation ◽  
Bone Mass ◽  
Rat Model ◽  
Sclerostin Antibody

scholarly journals Sclerostin Antibody Reverses Bone Loss by Increasing Bone Formation and Decreasing Bone Resorption in a Rat Model of Male Osteoporosis

Endocrinology ◽  
2017 ◽  
Vol 159 (1) ◽  
pp. 260-271 ◽  
Author(s):  
Xiaodong Li ◽  
Michael S Ominsky ◽  
Kelly S Villasenor ◽  
Qing-Tian Niu ◽  
Frank J Asuncion ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Bone Loss ◽  
Bone Formation ◽  
Rat Model ◽  
Male Osteoporosis ◽  
Sclerostin Antibody

Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength

2010 ◽  
Vol 25 (5) ◽  
pp. 948-959 ◽  
Author(s):  
Michael S Ominsky ◽  
Fay Vlasseros ◽  
Jacquelin Jolette ◽  
Susan Y Smith ◽  
Brian Stouch ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Formation ◽  
Bone Strength ◽  
Bone Mineral ◽  
Mineral Density ◽  
Cynomolgus Monkeys ◽  
Sclerostin Antibody

Changes in bone metabolism associated with exposure to industrial vibration

2020 ◽  
pp. 766-766
Author(s):  
A. V. Sukhova ◽  
E. N. Kryuchkova
Keyword(s):  
Bone Mineral Density ◽  
Alkaline Phosphatase ◽  
Bone Resorption ◽  
Bone Formation ◽  
Bone Metabolism ◽  
Biochemical Markers ◽  
Mineral Density ◽  
Local Vibration ◽  
Markers Of Bone Formation

The influence of general and local vibration on bone remodeling processes is investigated. The interrelations between the long - term exposure of industrial vibration and indicators of bone mineral density (T-and Z-criteria), biochemical markers of bone formation (osteocalcin, alkaline phosphatase) and bone resorption (ionized calcium, calcium/creatinine) were established.

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