Effects of diet-induced obesity and voluntary wheel running on bone mechanical properties from male young C57/6J mice

Bone ◽  
2011 ◽  
Vol 48 ◽  
pp. S177
Author(s):  
H. Ma ◽  
M. Silvennoinen ◽  
S. Torvinen ◽  
R. Rinnankoski-Tuikka ◽  
H. Kainulainen ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Wheel Running ◽  
Voluntary Wheel Running ◽  
Bone Mechanical Properties ◽  
Diet Induced Obesity ◽  
Voluntary Wheel

Effects of diet-induced obesity and voluntary wheel running on the axial and peripheral skeleton microstructure in mice

Bone ◽  
2010 ◽  
Vol 47 ◽  
pp. S86
Author(s):  
H. Ma ◽  
T. Turpeinen ◽  
S. Torvinen ◽  
M. Silvennoinen ◽  
R. Rinnankoski-Tuikka ◽  
...  
Keyword(s):  
Wheel Running ◽  
Voluntary Wheel Running ◽  
Diet Induced Obesity ◽  
Peripheral Skeleton ◽  
Voluntary Wheel

Effects of Diet-Induced Obesity and Voluntary Wheel Running on Bone Properties in Young Male C57BL/6J Mice

2010 ◽  
Vol 86 (5) ◽  
pp. 411-419 ◽  
Author(s):  
Hongqiang Ma ◽  
Sira Torvinen ◽  
Mika Silvennoinen ◽  
Rita Rinnankoski-Tuikka ◽  
Heikki Kainulainen ◽  
...  
Keyword(s):  
Wheel Running ◽  
Young Male ◽  
Voluntary Wheel Running ◽  
Diet Induced Obesity ◽  
Bone Properties ◽  
Voluntary Wheel

EFFECTS OF VOLUNTARY WHEEL RUNNING ON THE DEVELOPMENT OF DIET-INDUCED OBESITY IN C57BL/6 MICE

2001 ◽  
Vol 33 (5) ◽  
pp. S336
Author(s):  
Stephanie M. Jimenez ◽  
Peter F. Bodary ◽  
J Mark Davis ◽  
Russell R. Pate
Keyword(s):  
Wheel Running ◽  
Voluntary Wheel Running ◽  
Diet Induced Obesity ◽  
Voluntary Wheel

scholarly journals Effects of diet-induced obesity and voluntary wheel running on the microstructure of the murine distal femur

2011 ◽  
Vol 8 (1) ◽  
pp. 1 ◽  
Author(s):  
Hongqiang Ma ◽  
Tuomas Turpeinen ◽  
Mika Silvennoinen ◽  
Sira Torvinen ◽  
Rita Rinnankoski-Tuikka ◽  
...  
Keyword(s):  
Distal Femur ◽  
Wheel Running ◽  
Voluntary Wheel Running ◽  
Diet Induced Obesity ◽  
Voluntary Wheel

scholarly journals Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action

2019 ◽  
Vol 126 (4) ◽  
pp. 993-1005 ◽  
Author(s):  
Emilie Dalbram ◽  
Astrid L. Basse ◽  
Juleen R. Zierath ◽  
Jonas T. Treebak
Keyword(s):  
Insulin Action ◽  
Wheel Running ◽  
Body Weight Gain ◽  
Internal Clock ◽  
Time Of Day ◽  
Glucose Disposal ◽  
Dark Phase ◽  
Voluntary Wheel Running ◽  
Diet Induced Obesity ◽  
Voluntary Wheel

Metabolic dysfunction and Type 2 diabetes are associated with perturbed circadian rhythms. However, exercise appears to ameliorate circadian disturbances, as it can phase-shift or reset the internal clock system. Evidence is emerging that exercise at a distinct time of day can correct misalignments of the circadian clock and influence energy metabolism. This suggests that timing of exercise training can be important for the prevention and management of metabolic dysfunction. In this study, obese, high-fat diet-fed mice were subjected to voluntary wheel running (VWR) at two different periods of the day to determine the effects of time-of-day-restricted VWR on basal and insulin-stimulated glucose disposal. VWR in the late dark phase reduced body weight gain compared with VWR in the beginning of the dark phase. Conversely, time-of-day-restricted VWR did not influence insulin action and glucose disposal, since skeletal muscle and adipose tissue glucose uptake and insulin signaling remained unaffected. Protein abundance of the core clock proteins, brain-muscle arnt-like 1 (BMAL1), and circadian locomotor output control kaput (CLOCK), were increased in skeletal muscle after VWR, independent of whether mice had access to running wheels in the early or late dark phase. Collectively, we provide evidence that VWR in the late dark phase ameliorates diet-induced obesity without altering insulin action or glucose homeostasis. NEW & NOTEWORTHY Exercise appears to ameliorate circadian disturbances as it can entrain the internal clock system. We provide evidence that voluntary wheel running increases core clock protein abundance and influences diet-induced obesity in mice in a time-of-day-dependent manner. However, the effect of time-of-day-restricted voluntary wheel running on body weight gain is not associated with enhanced basal- and insulin-stimulated glucose disposal, suggesting that time-of-day-restricted voluntary wheel running affects energy homeostasis rather than glucose homeostasis.

scholarly journals Voluntary Wheel Running Selectively Augments Insulin-Stimulated Vasodilation in Arterioles from White Skeletal Muscle of Insulin-Resistant Rats

2012 ◽  
Vol 19 (8) ◽  
pp. 729-738 ◽  
Author(s):  
Catherine R. Mikus ◽  
Bruno T. Roseguini ◽  
Grace M. Uptergrove ◽  
E. Matthew Morris ◽  
Randy Scott Rector ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Wheel Running ◽  
Voluntary Wheel Running ◽  
Insulin Resistant ◽  
Voluntary Wheel

scholarly journals The Effect of Voluntary Wheel Running on Muscle Mass, Mitochondrial Function and Oxidative Damage in Sod1???/???mice

2006 ◽  
Vol 38 (Suppl 1) ◽  
pp. S12
Author(s):  
Michael S. Lustgarten ◽  
Young C. Jang ◽  
Wook Song ◽  
Yuhong Liu ◽  
Anson Pierce ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Muscle Mass ◽  
Mitochondrial Function ◽  
Wheel Running ◽  
Voluntary Wheel Running ◽  
Voluntary Wheel

P.1.05 Involvement of DARPP-32, FosB, and dynorphin in voluntary wheel running

2008 ◽  
Vol 18 ◽  
pp. s5-s6 ◽  
Author(s):  
A. Borgkvist ◽  
E.J. Nestler ◽  
P. Greengard ◽  
G. Fisone ◽  
S. Brené
Keyword(s):  
Wheel Running ◽  
Voluntary Wheel Running ◽  
Voluntary Wheel
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