scholarly journals Age-related changes in bone density, geometry and biomechanical properties of the proximal femur: CT-based 3D hip structure analysis in normal postmenopausal women

Bone ◽  
2011 ◽  
Vol 48 (3) ◽  
pp. 627-630 ◽  
Author(s):  
Masako Ito ◽  
Tomoko Nakata ◽  
Akifumi Nishida ◽  
Masataka Uetani
2020 ◽  
Vol 21 (S2) ◽  
Author(s):  
Hayman Saddik ◽  
Riad Nasr ◽  
Antonio Pinti ◽  
Eric Watelain ◽  
Ibrahim Fayad ◽  
...  

2016 ◽  
Vol 24 (3) ◽  
pp. 362-366 ◽  
Author(s):  
Junichi Takada ◽  
Hiroshi Wada ◽  
Kousuke Iba ◽  
Kouichi Sasaki ◽  
Takayuki Dohke ◽  
...  

Purpose To evaluate the effect of combined use of ibandronate and eldecalcitol for 6 to 12 months on bone mineral density (BMD) and bone strength of the proximal femur in postmenopausal Japanese women with osteoporosis. Methods BMD and bone strength of the proximal femur were evaluated in 78 postmenopausal women (mean age, 73.6 years) who underwent treatment for osteoporosis with combined use of ibandronate and eldecalcitol for at least 6 months. BMD was measured at the lumbar spine, femoral neck, and total hip using dual-energy X-ray absorptiometry (DXA) at baseline and every 6 months thereafter. Hip structure analysis of the narrow neck and intertrochanter was performed by a radiologist using DXA images. Results Respectively for the lumbar spine, femoral neck, and total hip, BMD significantly increased (from baseline) by 4.54%, 2.31%, and 1.56% at 6 months and by 5.92%, 3.02%, and 2.70% at 12 months. In hip structure analysis, most parameters improved significantly. Respectively for the narrow neck and intertrochanter, BMD significantly increased (from baseline) by 2.37% and 2.71% at 6 months and by 3.46% and 3.52% at 12 months; cross-sectional area significantly increased by 1.83% and 3.39% at 6 months and by 2.91% and 3.46% at 12 months; section modulus significantly increased by 2.42% and 4.11% at 6 months and by 4.84% and 3.26% at 12 months; cortical thickness significantly increased by 2.49% and 3.33% at 6 months and by 3.73% and 3.37% at 12 months; and buckling ratio significantly decreased by 2.97% and 2.57% at 6 months and by 3.86% and 2.99% at 12 months. Conclusion Combined use of ibandronate and eldecalcitol for 6 months significantly improved bone strength of the proximal femur in postmenopausal Japanese women with osteoporosis.


2010 ◽  
Vol 29 (4) ◽  
pp. 458-465 ◽  
Author(s):  
Junichi Takada ◽  
Genichiro Katahira ◽  
Kousuke Iba ◽  
Takashi Yoshizaki ◽  
Toshihiko Yamashita

1995 ◽  
Vol 33 (4) ◽  
pp. 633
Author(s):  
Yang Gu Joo ◽  
Cheol Ho Sohn ◽  
Young Sik Pyun ◽  
Mi Ok Park ◽  
Soo Jhi Suh ◽  
...  

2016 ◽  
Vol 13 (4) ◽  
pp. 414-418 ◽  
Author(s):  
Takeshi Mochizuki ◽  
Koichiro Yano ◽  
Katsunori Ikari ◽  
Kosei Kawakami ◽  
Ryo Hiroshima ◽  
...  

2020 ◽  
Vol 26 (3) ◽  
pp. 147-154
Author(s):  
Thiran D Dias ◽  
Thilina S Palihawadana ◽  
Malitha Patabendige ◽  
Mary BC Motha ◽  
Hithanadura J de Silva

Objective To describe the ultrasound parameters of pelvic organs and their age-related changes in a cohort of asymptomatic postmenopausal women and to describe the prevalence of ultrasound-detected pathologies in a Sri Lankan population. Study design A large community-based longitudinal study using a randomly selected sample of postmenopausal women who have never used hormone replacement therapy. Main outcome measures Uterine, endometrial and ovarian measurements at pelvic ultrasonography as described by the International Endometrial Tumor Analysis and the International Ovarian Tumor Analysis groups. Results A total of 815 postmenopausal women were approached and all volunteered to participate. This included women between the ages of 45 and 74 years with a median (interquartile range (IQR)) of 62.0 (10.0) years. The median (IQR) uterine volume was 18.1 (17) ml, while the median (IQR) of right and left ovarian volumes were 17.3 (22.9) ml and 18.2 (21.5) ml. Both uterine and ovarian volumes showed an age-related decline (p < 0.01). Furthermore, the ovarian volumes demonstrated an increase in size with a higher body mass index (p < 0.03 for left and p < 0.01 for right, respectively). Median (IQR) endometrial thickness among the population was 3.0 (1.0) mm and there was no age-related change observed. Sixty-one women had an ultrasound-detected gynaecological pathology with a prevalence of 7.5% (95% confidence interval (CI) 5.6–9.5). Conclusions This study aimed at describing ultrasound parameters of pelvic organs among postmenopausal women of Sri Lanka was able to provide the reference values for uterine and ovarian volume among asymptomatic postmenopausal women. Both uterine and ovarian volumes demonstrated an age-related decline, whereas the endometrial thickness does not seem to relate to the age.


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