scholarly journals Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women

Bone ◽  
2010 ◽  
Vol 47 (1) ◽  
pp. 83-92 ◽  
Author(s):  
Anita Undale ◽  
Bhuma Srinivasan ◽  
Matthew Drake ◽  
Louise McCready ◽  
Elizabeth Atkinson ◽  
...  
Bone ◽  
2011 ◽  
Vol 48 (3) ◽  
pp. 671
Author(s):  
Anita Undale ◽  
Bhuma Srinivasan ◽  
Matthew Drake ◽  
Louise McCready ◽  
Elizabeth Atkinson ◽  
...  

Climacteric ◽  
2011 ◽  
Vol 14 (1) ◽  
pp. 105-111 ◽  
Author(s):  
A. Tarakida ◽  
K. Iino ◽  
K. Abe ◽  
R. Taniguchi ◽  
T. Higuchi ◽  
...  

1993 ◽  
Vol 53 (5) ◽  
pp. 307-311 ◽  
Author(s):  
M. Revel ◽  
M. A. Mayoux-Benhamou ◽  
J. P. Rabourdin ◽  
F. Bagheri ◽  
C. Roux

2015 ◽  
Vol 38 (14) ◽  
pp. 1407-1414
Author(s):  
Juha Suuronen ◽  
Samu Sjöblom ◽  
Risto Honkanen ◽  
Heli Koivumaa-Honkanen ◽  
Heikki Kröger ◽  
...  

The Lancet ◽  
1987 ◽  
Vol 329 (8542) ◽  
pp. 1105-1108 ◽  
Author(s):  
C. Christiansen ◽  
B.J. Riis ◽  
P. Rødbro

2020 ◽  
Vol 9 (7) ◽  
pp. R158-R172 ◽  
Author(s):  
Alessandro Brancatella ◽  
Claudio Marcocci

Thyroid hormones stimulate bone turnover in adults by increasing osteoclastic bone resorption. TSH suppressive therapy is usually applied in patients with differentiated thyroid cancer (DTC) to improve the disease outcome. Over the last decades several authors have closely monitored the potential harm suffered by the skeletal system. Several studies and meta-analyses have shown that chronic TSH suppressive therapy is safe in premenopausal women and men. Conversely, in postmenopausal women TSH suppressive therapy is associated with a decrease of bone mineral density, deterioration of bone architecture (quantitative CT, QCT; trabecular bone score, TBS), and, possibly, an increased risk of fractures. The TSH receptor is expressed in bone cells and the results of experimental studies in TSH receptor knockout mice and humans on whether low TSH levels, as opposed to solely high thyroid hormone levels, might contribute to bone loss in endogenous or exogenous thyrotoxicosis remain controversial. Recent guidelines on the use of TSH suppressive therapy in patients with DTC give value not only to its benefit on the outcome of the disease, but also to the risks associated with exogenous thyrotoxicosis, namely menopause, osteopenia or osteoporosis, age >60 years, and history of atrial fibrillation. Bone health (BMD and/or preferably TBS) should be evaluated in postmenopausal women under chronic TSH suppressive therapy or in those patients planning to be treated for several years. Antiresorptive therapy could also be considered in selected cases (increased risk of fracture or significant decline of BMD/TBS during therapy) to prevent bone loss.


2001 ◽  
Vol 84 (8) ◽  
pp. 1047-1051 ◽  
Author(s):  
T Saarto ◽  
L Vehmanen ◽  
I Elomaa ◽  
M Välimäki ◽  
P Mäkelä ◽  
...  

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