Absence of bone remodeling compartment canopies correlates with deficient bone formation in post-menopausal women

Bone ◽  
2010 ◽  
Vol 46 ◽  
pp. S67-S68
Author(s):  
Thomas Andersen ◽  
Ellen Hauge ◽  
Jens Bollerslev ◽  
Jean-Marie Delaisse
Keyword(s):  
Bone Formation ◽  
Bone Remodeling ◽  
Menopausal Women ◽  
Post Menopausal

Correlation between Absence of Bone Remodeling Compartment Canopies, Reversal Phase Arrest, and Deficient Bone Formation in Post-Menopausal Osteoporosis

2014 ◽  
Vol 184 (4) ◽  
pp. 1142-1151 ◽  
Author(s):  
Thomas L. Andersen ◽  
Ellen M. Hauge ◽  
Lars Rolighed ◽  
Jens Bollerslev ◽  
Per Kjærsgaard-Andersen ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Remodeling ◽  
Phase Arrest ◽  
Post Menopausal Osteoporosis ◽  
Reversal Phase ◽  
Post Menopausal ◽  
Menopausal Osteoporosis

Pravastatin therapy increases procollagen I N-terminal propeptide (PINP), a marker of bone formation in post-menopausal women

2001 ◽  
Vol 308 (1-2) ◽  
pp. 133-137 ◽  
Author(s):  
Jose M Mostaza ◽  
Concepción De la Piedra ◽  
Manuel Dı́az Curiel ◽  
Rocı́o Peña ◽  
Carlos Lahoz
Keyword(s):  
Bone Formation ◽  
Menopausal Women ◽  
Post Menopausal

scholarly journals COMPARISON OF THE EFFECTS OF WALKING AND BENCH-STEP EXERCISE ON OSTEOCALCIN AND CTX-1 IN POST-MENOPAUSAL WOMEN WITH OSTEOPENIA

2017 ◽  
Vol 20 (02) ◽  
pp. 1750012
Author(s):  
Ignatio Rika Haryono ◽  
Angela Tulaar ◽  
Herawati Sudoyo ◽  
Ambrosius Purba ◽  
Murdani Abdullah ◽  
...  
Keyword(s):  
Bone Formation ◽  
Wilcoxon Test ◽  
Enzyme Linked Immunosorbent Assay ◽  
Test Results ◽  
T Score ◽  
Menopausal Women ◽  
Before And After ◽  
Walking Exercise ◽  
The Difference ◽  
Post Menopausal

Purpose: Bench-step exercise produces biomechanical movements beneficial to improve bone remodeling. However, no studies have confirmed the effects of bench-step exercise (BE) on bone formation and resorption. The goal of this study is to compare the effects of bench-step and walking exercise (WE) on changes in osteocalcin and CTX-1 levels. Methods: Fifty-nine sedentary post-menopausal women with osteopenia (T-score between [Formula: see text]1 and [Formula: see text]2.5) were randomly divided into two groups: WE group ([Formula: see text]) and BE group ([Formula: see text]). Subjects performed 12 weeks of exercise. The osteocalcin and CTX-1 levels were analyzed using enzyme-linked immunosorbent assay. Independent [Formula: see text]-test or Wilcoxon test was used to analyze the osteocalcin and CTX-1 levels. The difference in changes in the osteocalcin and CTX-1 between the groups before and after was analyzed using Mann–Whitney test. Results: The results showed a significant increase in the osteocalcin and CTX-1 levels in both groups ([Formula: see text]). The increased levels of osteocalcin between groups were not statistically different ([Formula: see text]). The increase in CTX-1 resulting from BE was lower than that from WE ([Formula: see text]). Conclusion: This study indicates that BE may inhibit resorption stronger than WE.

The Effects of Therapy with Oestriol Succinate and Ethinyl Oestradiol on the Haemostatic Mechanism in Post-Menopausal Women

1976 ◽  
Vol 35 (02) ◽  
pp. 403-414 ◽  
Author(s):  
Terence Davies ◽  
Gillian Fieldhouse ◽  
George P. McNicol
Keyword(s):  
Coagulation Factors ◽  
Factor Vii ◽  
Oestrogen Therapy ◽  
Qualitative And Quantitative ◽  
Lysis Activity ◽  
Menopausal Women ◽  
Increased Sensitivity ◽  
Post Menopausal ◽  
Incremental Increase ◽  
Ethinyl Oestradiol

SummaryThe effects on the haemostatic mechanism of oestrogen therapy, given to prevent bone loss in post-menopausal women, have been investigated. Oestriol succinate was given orally to 10 women at a level of 2 mg/day for 1 month and for a further 3 months with incremental increase of 2 mg each month. 6 of the 10 women were subsequently treated with 25 μg/day orally of ethinyl oestradiol. Oestriol succinate therapy resulted in a small increase in the level of factor VII, a decrease in factor VIII concentration and increased sensitivity of platelets to aggregating agents. Ethinyl oestradiol treatment resulted in much more widespread changes with marked increases in coagulation factors VII, VIII, IX and X, decreased levels of antithrombin and dramatic increases in circulating plasminogen levels and euglobulin lysis activity. The data suggested that the nature of oestrogens employed therapeutically is important in determining the qualitative and quantitative effect of oestrogen therapy on components of the haemostatic mechanism.

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