Bone sialoprotein, but not osteopontin, deficiency impairs the mineralization of regenerating bone during cortical defect healing

Bone ◽  
2010 ◽  
Vol 46 (2) ◽  
pp. 447-452 ◽  
Author(s):  
Laurent Monfoulet ◽  
Luc Malaval ◽  
Jane E. Aubin ◽  
Susan R. Rittling ◽  
Alain P. Gadeau ◽  
...  
Keyword(s):  
Bone Sialoprotein ◽  
Defect Healing ◽  
Cortical Defect

Absence of bone sialoprotein (BSP) impairs cortical defect repair in mouse long bone

Bone ◽  
2009 ◽  
Vol 45 (5) ◽  
pp. 853-861 ◽  
Author(s):  
Luc Malaval ◽  
Laurent Monfoulet ◽  
Thierry Fabre ◽  
Laurent Pothuaud ◽  
Reine Bareille ◽  
...  
Keyword(s):  
Bone Sialoprotein ◽  
Long Bone ◽  
Cortical Defect ◽  
Defect Repair

scholarly journals Marrow compartment contribution to cortical defect healing

2017 ◽  
Vol 89 (1) ◽  
pp. 119-123 ◽  
Author(s):  
Magnus Bernhardsson ◽  
Love Tätting ◽  
Olof Sandberg ◽  
Jörg Schilcher ◽  
Per Aspenberg
Keyword(s):  
Defect Healing ◽  
Cortical Defect

Bone sialoprotein mRNA and protein expression in human multiple myeloma cell lines and patients

2000 ◽  
Vol 111 (4) ◽  
pp. 1118-1121 ◽  
Author(s):  
A. Bellahcene ◽  
I. Van Riet ◽  
C. de Greef ◽  
N. Antoine ◽  
M. F. Young ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Protein Expression ◽  
Cell Lines ◽  
Myeloma Cell ◽  
Bone Sialoprotein ◽  
Multiple Myeloma Cell ◽  
Human Multiple Myeloma ◽  
Mrna And Protein Expression

scholarly journals A rat osteogenic cell line (UMR 106-01) synthesizes a highly sulfated form of bone sialoprotein.

1990 ◽  
Vol 265 (9) ◽  
pp. 5285-5291
Author(s):  
R J Midura ◽  
D J McQuillan ◽  
K J Benham ◽  
L W Fisher ◽  
V C Hascall
Keyword(s):  
Cell Line ◽  
Bone Sialoprotein ◽  
Osteogenic Cell ◽  
Umr 106

scholarly journals A Radiological Scoring System for Differentiation between Enchondroma and Chondrosarcoma

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3558
Author(s):  
Shinji Miwa ◽  
Norio Yamamoto ◽  
Katsuhiro Hayashi ◽  
Akihiko Takeuchi ◽  
Kentaro Igarashi ◽  
...  
Keyword(s):  
Scoring System ◽  
Radiological Finding ◽  
Final Diagnosis ◽  
Radiological Findings ◽  
Abnormal Signal ◽  
Cortical Defect ◽  
Diagnostic Usefulness ◽  
Radiological Score ◽  
Sensitivity Specificity ◽  
Cartilaginous Tumors

Background: It is challenging to differentiate between enchondromas and atypical cartilaginous tumors (ACTs)/chondrosarcomas. In this study, correlations between radiological findings and final diagnosis were investigated in patients with central cartilaginous tumors. Methods: To evaluate the diagnostic usefulness of radiological findings, correlations between various radiological findings and final diagnoses were investigated in a cohort of 81 patients. Furthermore, a new radiological scoring system was developed by combining radiological findings. Results: Periosteal reaction on X-ray (p = 0.025), endosteal scalloping (p = 0.010) and cortical defect (p = 0.002) on CT, extraskeletal mass (p < 0.001), multilobular lesion (p < 0.001), abnormal signal in adjacent tissue (p = 0.004) on MRI, and increased uptake in bone scan (p = 0.002) and thallium scan (p = 0.027) was significantly correlated with final diagnoses. Based on the correlations between each radiological finding and postoperative histological diagnosis, a radiological scoring system combining these findings was developed. In another cohort of 17 patients, the sensitivity, specificity, and accuracy of the radiological score rates for differentiation between enchondromas and ACTs/chondrosarcomas were 88%, 89%, and 88%, respectively (p = 0.003). Conclusion: Radiological assessment with combined radiological findings is recommended to differentiate between enchondromas and ACT/chondrosarcomas.

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