Quantitative micro-computed tomography: A non-invasive method to assess equivalent bone mineral density

Bone ◽  
2008 ◽  
Vol 43 (2) ◽  
pp. 302-311 ◽  
Author(s):  
Ara Nazarian ◽  
Brian D. Snyder ◽  
David Zurakowski ◽  
Ralph Müller
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Micro Computed Tomography ◽  
Mineral Density ◽  
Non Invasive ◽  
Invasive Method

scholarly journals Influence of reconstruction parameters of micro-computed tomography on the analysis of bone mineral density

2020 ◽  
Vol 50 (2) ◽  
pp. 153
Author(s):  
Hugo Gaêta-Araujo ◽  
Eduarda Helena Leandro Nascimento ◽  
Danieli Moura Brasil ◽  
Daniela Verardi Madlum ◽  
Francisco Haiter-Neto ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Micro Computed Tomography ◽  
Mineral Density

Further improvements on the factors affecting bone mineral density measured by quantitative micro-computed tomography

Bone ◽  
2012 ◽  
Vol 50 (3) ◽  
pp. 611-618 ◽  
Author(s):  
Vahid Entezari ◽  
Vartan Vartanians ◽  
David Zurakowski ◽  
Nipun Patel ◽  
Roberto J. Fajardo ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Micro Computed Tomography ◽  
Mineral Density ◽  
Factors Affecting

VALIDATION OF A BONE MINERAL DENSITY CALIBRATION PROTOCOL FOR MICRO-COMPUTED TOMOGRAPHY

2017 ◽  
Vol 17 (01) ◽  
pp. 1750015
Author(s):  
FABIO BARUFFALDI ◽  
ROSSELLA STOICO ◽  
SIMONE TASSANI ◽  
LAURA MECOZZI ◽  
STEFANO FALCIONI ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Bone Structure ◽  
Tissue Type ◽  
Micro Ct ◽  
Micro Computed Tomography ◽  
Mineral Density ◽  
Calibration Protocol

Micro-computed tomography (micro-CT) is widely used for in vitro studies to characterize bone structure at the resolution of 10–100 microns. However, a densitometric calibration protocol is necessary to convert the X-ray attenuation coefficient provided by micro-CT in bone mineral density (BMD). The lastest one has an important role to improve the accuracy of subject-specific finite element models. This work presents a simple calibration protocol based on the use of solid hydroxyapatite phantoms with the correction of the beam hardening effect. The method was validated in comparison to ashing measures of cortical and trabecular human bone. In addition, bone samples tissue mineral density (TMD) was calculated with two different methods. The correlation between ash density and BMD was linear both for cortical ([Formula: see text]) and trabecular bone ([Formula: see text]). The analysis stratified by tissue type versus the pooled analysis confirmed the validity of a common linear model for both types of tissue ([Formula: see text]). Despite its simplicity, the correlation obtained in this work does not depend on the acquisition settings of the micro-CT. TMD was shown to be dependent on the tissue investigated, with values in the range of 1.15–1.21[Formula: see text]mg/mm3 for trabecular bone, and 1.19–1.29[Formula: see text]mg/mm3 for cortical bone. Results are of some interest for generating micro finite elements models.

Bone Mineral Density Attenuation in Obstructive Sleep Apnea by Derived Computed Tomography Screening

2021 ◽  
Author(s):  
Sharon Daniel ◽  
Yafit Cohen-Freud ◽  
Ilan Shelef ◽  
Ariel Tarasiuk
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Bone Mineral ◽  
Clinical Information ◽  
Mineral Density ◽  
Peak Voltage ◽  
Arousal Index ◽  
Obstructive Sleep

Abstract The association between obstructive sleep apnea (OSA) and bone mineral density (BMD) is poorly elucidated with contradictory findings. We retrospectively explored the association between OSA and BMD by examining abdominal computed tomography (CT) vertebrae images using clinical information. We included 315 subjects (174 with OSA and 141 without OSA) who performed at least two CT scans (peak voltage of 120 kV). Bone mineral density was attenuated in those with OSA and increased age. BMD attenuation was not associated with the apnea–hypopnea score, nocturnal oxygen saturation, or arousal index. A multivariate linear regression indicated that OSA is associated with BMD attenuation after controlling for age, gender, and cardiovascular diseases. Here, we report that OSA is associated with BMD attenuation. Further studies are required to untangle the complex affect of OSA on BMD loss and possible clinical implication of vertebra depressed fracture or femoral neck fracture.

scholarly journals Evaluation of Bone Mineral Density by Computed Tomography in Patients with Obstructive Sleep Apnea

2016 ◽  
Vol 12 (01) ◽  
pp. 25-34 ◽  
Author(s):  
Satoshi Hamada ◽  
Kohei Ikezoe ◽  
Toyohiro Hirai ◽  
Tsuyoshi Oguma ◽  
Kiminobu Tanizawa ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Bone Mineral ◽  
Mineral Density ◽  
Obstructive Sleep
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