Fore-arm speed of sound in cystic fibrosis patients: correlation with bone mineral density and cortical wall thickness assessed using pQCT

Bone ◽  
2007 ◽  
Vol 40 (6) ◽  
pp. S61-S62
Author(s):  
O. LOUIS ◽  
K. Toye ◽  
S. Van Biervliet ◽  
I. Gies ◽  
S. Goemare ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Bone Mineral ◽  
Wall Thickness ◽  
Speed Of Sound ◽  
Mineral Density

scholarly journals IL-8 correlates with reduced baseline femoral neck bone mineral density in adults with cystic fibrosis: a single center retrospective study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Grace Y. Lam ◽  
Sameer Desai ◽  
Joey Fu ◽  
Xun Yang Hu ◽  
Jiah Jang ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Femoral Neck ◽  
Bone Mineral ◽  
Forced Expiratory Volume ◽  
Inflammatory Biomarkers ◽  
Mineral Density ◽  
Baseline Serum ◽  
Average Percentage ◽  
System Disease

AbstractCystic fibrosis (CF) is a multi-system disease that is characterized by lung disease due to recurrent airway infection and inflammation. Endocrine complications, such as CF bone disease (CFBD), are increasingly identified as patients are living longer. The cause of CFBD is multifactorial with chronic systemic inflammation theorized to be a contributing factor. Thus, we attempted to identify inflammatory biomarkers that are associated with CFBD. We conducted a retrospective observational study of 56 adult patients with CF with an average percentage predictive forced expiratory volume in one second (ppFEV1) of 73.7% (standard deviation: 30.0) who underwent baseline serum analysis for osteoprotegerin (OPG) and pro-inflammatory biomarkers (IL-1β, IL-6, IL-8 and TNF-α), and had repeated dual-energy x-ray absorptiometry (DXA) scans separated by at least 2 years to examine correlations between serum biomarkers and bone mineral density (BMD) measurements. Univariate linear regression model analysis demonstrated that serum IL-1β and IL-8, but not other pro-inflammatory markers, were negatively correlated with baseline BMD results. However, after accounting for confounding variables, only the relationship between IL-8 and left femoral neck BMD remained statistically significant. Additionally, IL-8 level was associated with BMD decline over time. These results suggest that IL-8 might play a unique role in the pathophysiology of CFBD relative to other pro-inflammatory cytokines but further study is warranted before firm conclusions can be made.

scholarly journals WS16.5 Comparison of cystic fibrosis adolescents with normal and low bone mineral density

2013 ◽  
Vol 12 ◽  
pp. S33 ◽  
Author(s):  
M. Mielus ◽  
D. Sands ◽  
B. Oralewska ◽  
M. Ołtarzewski ◽  
J. Walkowiak
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Bone Mineral ◽  
Mineral Density ◽  
Low Bone Mineral Density

Bone mineral density and lean body mass in children and adolescents with cystic fibrosis

Bone ◽  
2009 ◽  
Vol 45 ◽  
pp. S72
Author(s):  
M. van Huis ◽  
J.C. Escher ◽  
P.J.F.M. Merkus ◽  
N. van Eldik ◽  
J.J.E. Hendriks ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Children And Adolescents ◽  
Lean Body Mass ◽  
Body Mass ◽  
Bone Mineral ◽  
Mineral Density

Low Serum Bone Gamma-Carboxyglutamic Acid Protein Concentrations in Patients with Cystic Fibrosis: Correlation with Hormonal Parameters and Bone Mineral Density

1993 ◽  
Vol 39 (5-6) ◽  
pp. 197-201 ◽  
Author(s):  
Jean De Schepper ◽  
Johan Smitz ◽  
Isidoor Dab ◽  
Amnon Piepsz ◽  
Marc Jonckheer ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Bone Mineral ◽  
Mineral Density ◽  
Acid Protein ◽  
Carboxyglutamic Acid ◽  
Low Serum

scholarly journals Bone mineral density and quantitative ultrasound in children and adolescents with cystic fibrosis

2010 ◽  
Vol 9 ◽  
pp. S84 ◽  
Author(s):  
E. Hatziagorou ◽  
A. Christoforidis ◽  
V. Avramidou ◽  
E. Kazantzidou ◽  
F. Kirvassilis ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Children And Adolescents ◽  
Bone Mineral ◽  
Quantitative Ultrasound ◽  
Mineral Density
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