Vitamin D levels (25OHD): Do they have any effect on muscle mass (MM) and bone mineral content (BMC) in patients with chronic renal failure (CRF) undergoing haemodialysis (HD)

Bone ◽  
2006 ◽  
Vol 38 (5) ◽  
pp. S8-S9
Author(s):  
J. Fassi ◽  
G. Rosa Diez ◽  
M.S. Crucelegui ◽  
M. Trillini ◽  
H. Rivera Nuñez ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Bone Mineral Content ◽  
Muscle Mass ◽  
Bone Mineral ◽  
Mineral Content ◽  
Vitamin D Levels

Response of vitamin D binding protein and free vitamin D concentrations to vitamin D supplementation in hospitalized premature infants

2015 ◽  
Vol 28 (9-10) ◽  
Author(s):  
Corrine Hanson ◽  
Elizabeth Lyden ◽  
Amy Nelson ◽  
Melissa Thoene ◽  
Julie Wagner ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Premature Infants ◽  
Vitamin D3 ◽  
Mineral Content ◽  
Binding Protein ◽  
Vitamin D Binding Protein ◽  
Vitamin D Levels ◽  
Free Vitamin D

AbstractThe objective of this study was to evaluate the relationship between 25(OH)D, Vitamin D Binding Protein (DBP), and free vitamin D in premature infants.Thirty-two infants <32 weeks’ gestation were randomized to two different levels of vitamin D3 supplementation (400 vs. 800 IU/day). 25(OH)D levels were measured by LC-MS/MS; DBP was measured by validated ELISA. Free vitamin D was calculated using molar ratios of 25(OH)D and DBP. The Wilcoxon signed rank test was used to compare DBP, free D and 25(OH)D levels; Spearman’s correlation coefficients were used to assess correlations.The mean gestational age at birth was 30.5 weeks; mean birth weight was 1405 g. Mean 25(OH)D levels at birth were 17.3 ng/mL; DBP levels were 297 mg/L, and estimated free vitamin D levels were 18.9. There was a statistically significant change in 25(OH)D levels after 8 weeks (24.6 vs. 39.1 ng/mL in the 400 vs. 800 group, respectively, p=0.02). DBP levels from birth to 8 weeks showed a statistically significant decrease (267 vs. 208, p=0.04). Estimated free 25(OH)D concentrations increased over the study period, from 18.9 at birth to 64.7 at 8 weeks of age (p=0.0001). Free vitamin D levels at birth were associated with global DEXA bone mineral content at discharge from the NICU (r=0.58, p=0.05).Supplementation with vitamin D3 increased the free portion of the vitamin D metabolite, providing increased bioavailable substrate. Improved free vitamin D levels may improve measurable outcomes such as bone mineral content and deserve further evaluation.

scholarly journals Relation of Serum 25(OH)-Vitamin D to Fat Mass and Lean Mass, Bone Mineral Content and Body Composition in Adults – a DXA-Based Study

2018 ◽  
Vol 45 (2) ◽  
pp. 5-11
Author(s):  
M. G. Nikolova ◽  
A. B. Penkov ◽  
M. A. Boyanov
Keyword(s):  
Vitamin D ◽  
Body Composition ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Fat Mass ◽  
Lean Mass ◽  
Mineral Content ◽  
Fat Free Mass ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D

Abstract Obesity has been linked with vitamin D deficiency in a number of cross-sectional studies, reviews and meta-analyses. The aim of the present study was to assess the correlations of plasma 25(OH) vitamin D levels with indices of body composition examined by DXA with an emphasis on lean and bone mass as well as on indices such as android/gynoid fat, appendicular lean mass, fat-mass indexes (FMI) and fat-free mass indexes (FFMI). 62 adult subjects consented to participate – 27 men (43.5%) and 35 women (56.5%). Their mean age was 45.3 ± 9.5 years. Fan-beam dual-energy X-ray (DXA) body composition analysis was performed on a Lunar Prodigy Pro bone densitometer with software version 12.30. Vitamin D was measured by electro-hemi-luminescent detection as 25(OH) D Total (ECLIA, Elecsys 2010 analyzer, Roche Diagnostics). Statistical analyses were done using the SPSS 23.0 statistical package. The serum 25(OH)D level was correlated significantly only to the whole body bone mineral content, the appendicular lean mass index (ALMI) and the ALM-to-BMI index, underlining a predominant role for lean and fat-free mass. Vitamin D showed a very weak correlation to % Body Fat and the Fat Mass Index (FMI) in men only. Moreover, the multiple regression equation including the associated parameters could explain only 7% of the variation in the serum 25(OH) D levels. Our conclusion was, that there are differences in the associations of the vitamin D levels with the different body composition indices, but these associations are generally very weak and therefore – negligible.

A longitudinal study of bone-mineral content and intestinal calcium absorption in patients with chronic renal failure

Metabolism ◽  
1979 ◽  
Vol 28 (11) ◽  
pp. 1114-1121 ◽  
Author(s):  
J.R. Juttmann ◽  
J.C.W. Hagenouw-Taal ◽  
L.D.F. Lameyer ◽  
A.M. Ruis ◽  
J.C. Birkenhäger
Keyword(s):  
Renal Failure ◽  
Longitudinal Study ◽  
Chronic Renal Failure ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Calcium Absorption ◽  
Intestinal Calcium Absorption
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