The relationship between vitamin D and parathyroid hormone: calcium homeostasis, bone turnover, and bone mineral density in postmenopausal women with established osteoporosis

Bone ◽  
2004 ◽  
Vol 35 (1) ◽  
pp. 312-319 ◽  
Author(s):  
O Sahota ◽  
M.K Mundey ◽  
P San ◽  
I.M Godber ◽  
N Lawson ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Bone Turnover ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Calcium Homeostasis ◽  
Mineral Density ◽  
Established Osteoporosis ◽  
The Relationship

The relationship of vitamin D status to bone mineral density in an Italian population of postmenopausal women

2005 ◽  
Vol 16 (12) ◽  
pp. 1691-1697 ◽  
Author(s):  
Nazzarena Malavolta ◽  
Loredana Pratelli ◽  
Marilena Frigato ◽  
Rita Mulè ◽  
Maria Lucia Mascia ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Italian Population ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Relationship Of ◽  
The Relationship

scholarly journals Vitamin D and parathyroid hormone in relation to bone mineral density in postmenopausal women

2012 ◽  
Vol 69 (3) ◽  
pp. 243-248 ◽  
Author(s):  
Marina Vuceljic ◽  
Olivera Ilic-Stojanovic ◽  
Milica Lazovic ◽  
Mirko Grajic
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Epidemiological Data ◽  
Significant Negative Correlation ◽  
Vitamin D Insufficiency ◽  
Mineral Density ◽  
Hydroxyvitamin D

Background/Aim. Despite vitamin D insufficiency being widely reported, in Serbia the epidemiological data lack information regarding vitamin D status in the sera of postmenopausal women. The aim of this study was to establish the prevalence of inadequate serum 25-hydroxyvitamin D [25(OH)D] concentrations in postmenopausal Serbian women with seasonal variations of 25(OH)D, in relation to parathyroid hormone (PTH) and bone mineral density (BMD). Methods. A total of 95 postmenopausal women, mean age 65.1 ? 9.08 years, were examined. Measurements of 25(OH)D and PTH were performed both in the winter and the summer period, using electrochemiluminiscence immunoassays. BMD (g/cm2) was measured by the dualenergy x-Ray absortimetry (DXA) method on the spine and hip areas. Results. A decreased value of vitamin D (< 75 nmol/L) in 88.4% of postmenopausal women and an elevated level of PTH (> 65 pg/mL) in 25.3% of the cases were found. Elevated PTH varied individually, but was mostly increased if 25(OH)D was equal or lower than 37.6 nmol/L. 25(OH)D insufficiency was found in winter in 94.5% and in summer in 80% of the cases (p < 0.01). The mean of the PTH was higher (p < 0.05) in winter than in summer. A significant negative correlation between 25(OH)D and PTH (p < 0.001) was proved. Correlation between 25(OH)D and PTH with BMD at lumbar spine was established in the whole group, but at the femoral neck in women aged over 65 years (p < 0.05). Conclusion. Our results showed a high prevalence of vitamin D insufficiency (88.4%) among postmenopausal women. The levels of 25(OH)D and PTH changed significantly according to the season.

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