Synthesis and anti-inflammatory activity evaluation of a novel series of 6-phenoxy-[1,2,4]triazolo[3,4- a ]phthalazine-3-carboxamide derivatives

2016 ◽  
Vol 26 (6) ◽  
pp. 1576-1579 ◽  
Author(s):  
Da-Chuan Liu ◽  
Guo-Hua Gong ◽  
Cheng-Xi Wei ◽  
Xue-Jun Jin ◽  
Zhe-Shan Quan
Keyword(s):  
Inflammatory Activity ◽  
Activity Evaluation ◽  
Anti Inflammatory

Synthesis and anti-inflammatory activity evaluation of unsymmetrical selenides

2008 ◽  
Vol 43 (7) ◽  
pp. 1432-1437 ◽  
Author(s):  
Federico Martínez-Ramos ◽  
Hector Salgado-Zamora ◽  
Maria Elena Campos-Aldrete ◽  
Estela Melendez-Camargo ◽  
Yazmín Márquez-Flores ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Activity Evaluation ◽  
Anti Inflammatory

scholarly journals Sesquiterpenoids and Their Anti-Inflammatory Activity: Evaluation of Ainsliaea yunnanensis

Molecules ◽  
2019 ◽  
Vol 24 (9) ◽  
pp. 1701
Author(s):  
Jinjie Li ◽  
Xiuting Li ◽  
Xin Wang ◽  
Xiangjian Zhong ◽  
Linlin Ji ◽  
...  
Keyword(s):  
Nlrp3 Inflammasome ◽  
Ethanolic Extract ◽  
The Self ◽  
Inflammatory Activity ◽  
Spectroscopic Methods ◽  
Activity Evaluation ◽  
Caspase 1 ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Four new sesquiterpenoids (1–4) and six known sesquiterpenoids (5–10), were isolated from the EtOAc phase of the ethanolic extract of Ainsliaea yunnanensis. Their structures were established by spectroscopic methods, including 1-D, 2-D NMR and HPLC-MS. All compounds were tested for their anti-inflammatory effect by the inhibition of the activity of NLRP3 inflammasome by blocking the self-slicing of pro-caspase-1, which is induced by nigericin, then the secretion of mature IL-1β, mediated by caspase-1, was suppressed. Unfortunately none of the compounds showed an anti-inflammatory effect.

scholarly journals Synthesis and anti-inflammatory activity evaluation of novel triazolyl-isatin hybrids

2016 ◽  
Vol 31 (6) ◽  
pp. 1520-1526 ◽  
Author(s):  
Pramod K. Sharma ◽  
Sakshi Balwani ◽  
Divya Mathur ◽  
Shashwat Malhotra ◽  
Brajendra K. Singh ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Activity Evaluation ◽  
Anti Inflammatory

Isolation and Anti-Inflammatory Activity Evaluation of Triterpenoids and a Monoterpenoid Glycoside fromHarpagophytum procumbens

Planta Medica ◽  
2010 ◽  
Vol 76 (16) ◽  
pp. 1892-1896 ◽  
Author(s):  
Jin Qi ◽  
Na Li ◽  
Jia-Hong Zhou ◽  
Bo-Yang Yu ◽  
Samuel Qiu
Keyword(s):  
Inflammatory Activity ◽  
Activity Evaluation ◽  
Anti Inflammatory

Synthesis and Anti-inflammatory Activity Evaluation of Novel 7-Alkoxy-1-amino-4,5-dihydro[1,2,4]triazole[4,3-a]quinolines

2008 ◽  
Vol 341 (5) ◽  
pp. 288-293 ◽  
Author(s):  
Xian-Yu Sun ◽  
Cheng-Xi Wei ◽  
Kyu-Yun Chai ◽  
Hu-Ri Piao ◽  
Zhe-Shan Quan
Keyword(s):  
Inflammatory Activity ◽  
Activity Evaluation ◽  
Anti Inflammatory

Norursane-type triterpenoids from Rosmarinus officinalis and their anti-inflammatory activity evaluation

Fitoterapia ◽  
2021 ◽  
pp. 104982
Author(s):  
Na Zhou ◽  
Ze-yu Wang ◽  
Wu Yong ◽  
Xiang-jian Zhong ◽  
Xin Wang ◽  
...  
Keyword(s):  
Rosmarinus Officinalis ◽  
Inflammatory Activity ◽  
Activity Evaluation ◽  
Anti Inflammatory

scholarly journals New thiopyridine complexes: design, electrochemical preparation and biological assessment

2019 ◽  
Vol 21 (4) ◽  
pp. 20-25
Author(s):  
Osama I. El-Sabbagh ◽  
Yamany B. Yamany ◽  
Hany A. Eldeab
Keyword(s):  
Inflammatory Activity ◽  
Biological Assessment ◽  
The Novel ◽  
Copper Metal ◽  
Chemical Methods ◽  
Reference Drug ◽  
Electrochemical Preparation ◽  
Activity Evaluation ◽  
Elemental Analyses ◽  
Anti Inflammatory

Abstract Novel complexes of Ru (III), Cu (II) and Au (III) (2–4) were prepared using 6-phenyl-2-thioxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile (HL, 1) adopting either electrochemical or traditional chemical methods. The electrochemical method is preferred in the synthesis of the complexes than the chemical one because it affords pure products with higher yields in shorter reaction time. The novel thiopyridine complexes were characterized by elemental analyses, IR, 1H, 19F-NMR, TGA and DTA measurements. The antimicrobial activity evaluation revealed that the complex bearing copper metal 3 has nearly the same activity as the reference drug ciprofloxacin. Anti-inflammatory activity evaluation showed that complex 4 containing gold displayed anti-inflammatory activity higher than the reference drug celecoxib upon using carrageenan rat hind paw edema method.

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