Total synthesis and biological evaluation of viscolin, a 1,3-diphenylpropane as a novel potent anti-inflammatory agent

2006 ◽  
Vol 16 (24) ◽  
pp. 6155-6160 ◽  
Author(s):  
Chung-Ren Su ◽  
Yuh-Chiang Shen ◽  
Ping-Chung Kuo ◽  
Yann-Lii Leu ◽  
Amooru G. Damu ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Biological Evaluation ◽  
Inflammatory Agent ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation

Total synthesis and biological evaluation of seven new anti-inflammatory oxacyclododecindione-type macrolactones

2020 ◽  
Vol 18 (30) ◽  
pp. 5906-5917
Author(s):  
Carina Weber ◽  
Nina Vierengel ◽  
Thorsten Walter ◽  
Torsten Behrendt ◽  
Tobias Lucas ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Inhibitory Activity ◽  
Biological Evaluation ◽  
Signalling Pathways ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation

Seven new macrolactones of the oxacyclododecindione family have been synthesized and tested for their inhibitory activity on TGF-β-inducible Smad2/3- as well as IL-4-inducible STAT6-dependent signalling pathways.

Synthesis and biological evaluation of a novel baicalein glycoside as an anti-inflammatory agent

2014 ◽  
Vol 744 ◽  
pp. 147-156 ◽  
Author(s):  
Kyun Ha Kim ◽  
Young-Don Park ◽  
Heejin Park ◽  
Keum-Ok Moon ◽  
Ki-Tae Ha ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Inflammatory Agent ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation

Neural Anti-Inflammatory Natural Product Periconianone A: Total Synthesis and Biological Evaluation

2019 ◽  
Vol 2019 (13) ◽  
pp. 2376-2381 ◽  
Author(s):  
Hanuman P. Kalmode ◽  
Suhag S. Patil ◽  
Kishor L. Handore ◽  
Paresh R. Athawale ◽  
Rambabu Dandela ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Biological Evaluation ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation

Design, synthesis and biological evaluation of hesperetin derivatives as potent anti-inflammatory agent

Fitoterapia ◽  
2017 ◽  
Vol 121 ◽  
pp. 212-222 ◽  
Author(s):  
Hai-Wen Ding ◽  
Ai-Ling Huang ◽  
Yi-Long Zhang ◽  
Bo Li ◽  
Chen Huang ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Inflammatory Agent ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation

Docking Studies, Synthesis and Biological Evaluation of β-aryl-β-hydroxy Propanoic Acids for Anti-inflammatory Activity

2017 ◽  
Vol 13 (2) ◽  
pp. 186-195 ◽  
Author(s):  
Jelena Savic ◽  
Sanda Dilber ◽  
Marina Milenkovic ◽  
Jelena Kotur-Stevuljevic ◽  
Bojan Markovic ◽  
...  
Keyword(s):  
Docking Studies ◽  
Biological Evaluation ◽  
Inflammatory Activity ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation

scholarly journals Xylochemical Synthesis and Biological Evaluation of Shancigusin C and Bletistrin G

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3224
Author(s):  
Leander Geske ◽  
Ulrich Kauhl ◽  
Mohamed E. M. Saeed ◽  
Anja Schüffler ◽  
Eckhard Thines ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Biological Activities ◽  
Biological Evaluation ◽  
Aromatic Substitution ◽  
Substitution Reactions ◽  
Total Syntheses ◽  
Wittig Olefination ◽  
Starting Point ◽  
Perkin Reaction ◽  
Synthesis And Biological Evaluation

The biological activities of shancigusin C (1) and bletistrin G (2), natural products isolated from orchids, are reported along with their first total syntheses. The total synthesis of shancigusin C (1) was conducted by employing the Perkin reaction to forge the central stilbene core, whereas the synthesis of bletistrin G (2) was achieved by the Wittig olefination followed by several regioselective aromatic substitution reactions. Both syntheses were completed by applying only renewable starting materials according to the principles of xylochemistry. The cytotoxic properties of shancigusin C (1) and bletistrin G (2) against tumor cells suggest suitability as a starting point for further structural variation.

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