scholarly journals Probing the in vivo biosynthesis of scytonemin, a cyanobacterial ultraviolet radiation sunscreen, through small scale stable isotope incubation studies and MALDI-TOF mass spectrometry

2011 ◽  
Vol 19 (22) ◽  
pp. 6620-6627 ◽  
Author(s):  
Carla S. Jones ◽  
Eduardo Esquenazi ◽  
Pieter C. Dorrestein ◽  
William H. Gerwick
Keyword(s):  
Mass Spectrometry ◽  
Stable Isotope ◽  
Ultraviolet Radiation ◽  
Small Scale ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof

A small-scale method for the preparation of plant N-linked glycans from soluble proteins for analysis by MALDI-TOF mass spectrometry

2009 ◽  
Vol 47 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Saskia R. Karg ◽  
Alexander D. Frey ◽  
Claudia Ferrara ◽  
Daniel K. Streich ◽  
Pablo Umaña ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Soluble Proteins ◽  
Small Scale ◽  
Maldi Tof Mass Spectrometry ◽  
Scale Method ◽  
Maldi Tof

Stable-Isotope-Assisted MALDI-TOF Mass Spectrometry for Accurate Determination of Nucleotide Compositions of PCR Products

1999 ◽  
Vol 71 (15) ◽  
pp. 3118-3125 ◽  
Author(s):  
Xian Chen ◽  
Zhengdong Fei ◽  
Lloyd M. Smith ◽  
E. Morton Bradbury ◽  
Vahid Majidi
Keyword(s):  
Mass Spectrometry ◽  
Stable Isotope ◽  
Accurate Determination ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof ◽  
Pcr Products

scholarly journals Quantifying the Matrix Metalloproteinase 2 (MMP2) Spatially in Tissues by Probe via MALDI Imaging Mass Spectrometry

2021 ◽  
Vol 9 ◽  
Author(s):  
Daojiang Yu ◽  
Peng Lai ◽  
Tao Yan ◽  
Kai Fang ◽  
Lei Chen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Matrix Metalloproteinase ◽  
Cancer Progression ◽  
Imaging Mass Spectrometry ◽  
Matrix Metalloproteinase 2 ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof ◽  
The Matrix ◽  
Important Approach

As a matrix metalloproteinase, the abnormal expression of MMP2 is associated with multiple biological processes, including tissue remodeling and cancer progression. Therefore, spatial analysis of MMP2 protein in tissues can be used as an important approach to evaluate the expression distribution of MMP2 in complex tissue environments, which will help the diagnosis and treatment of various diseases, including tissue or organ injuries. Moreover, this analysis will also help the evaluation of prognoses. However, MMP2 is difficult to be spatially determined by MALDI TOF mass spectrometry due to its large molecular weight (over 72 KD) and low content. Therefore, a new method should be developed to help this detection. Here, we have designed a specific MMP2 probe that closely binds to MMP2 protein in tissue. This probe has a Cl on Tyr at the terminal, which can provide two isotope peaks to help the accuracy quantitative of MMP2 protein. Based on this, we used the probe to determine the spatial expression of MMP2 in the tissues based on MALDI TOF mass spectrometry. This approach may help to study the influence of multifunctional proteases on the degree of malignancy in vivo.

scholarly journals Klebsiella MALDI TypeR: a web-based tool for Klebsiella identification based on MALDI-TOF mass spectrometry

2021 ◽  
pp. 103835
Author(s):  
Sébastien Bridel ◽  
Stephen C. Watts ◽  
Louise M. Judd ◽  
Taylor Harshegyi ◽  
Virginie Passet ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Web Based ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof

Partial Fluorination of Hydroxyl End-Capped Oligoesters Revealed by MALDI−TOF Mass Spectrometry

2001 ◽  
Vol 34 (7) ◽  
pp. 2389-2393 ◽  
Author(s):  
Weihua Ming ◽  
Xianwen Lou ◽  
Robert D. van de Grampel ◽  
Joost L. J. van Dongen ◽  
Rob van der Linde
Keyword(s):  
Mass Spectrometry ◽  
Maldi Tof Mass Spectrometry ◽  
Maldi Tof
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