Crystal structure, docking study and structure–activity relationship of carborane-containing androgen receptor antagonist 3-(12-hydroxymethyl-1,12-dicarba-closo-dodecaboran-1-yl)benzonitrile

Kiminori Ohta; Tokuhito Goto; Shinya Fujii; Masatoshi Kawahata; Akifumi Oda; Shigeru Ohta; Kentaro Yamaguchi; Shuichi Hirono; Yasuyuki Endo

doi:10.1016/j.bmc.2011.04.017

Crystal structure, docking study and structure–activity relationship of carborane-containing androgen receptor antagonist 3-(12-hydroxymethyl-1,12-dicarba-closo-dodecaboran-1-yl)benzonitrile

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2011.04.017 ◽

2011 ◽

Vol 19 (11) ◽

pp. 3540-3548 ◽

Cited By ~ 17

Author(s):

Kiminori Ohta ◽

Tokuhito Goto ◽

Shinya Fujii ◽

Masatoshi Kawahata ◽

Akifumi Oda ◽

...

Keyword(s):

Crystal Structure ◽

Androgen Receptor ◽

Receptor Antagonist ◽

Docking Study ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Androgen Receptor Antagonist ◽

Structure Activity ◽

Relationship Of

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Structure-activity relationship of nantenine, a novel 5-HT2A receptor antagonist and its analysis by molecular modeling

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)47568-9 ◽

2000 ◽

Vol 82 ◽

pp. 22

Author(s):

Yasushi Ohizumi-Indra ◽

Kimihiro Matsunaga ◽

Osamu Hoshino ◽

Masaji Ishiguro

Keyword(s):

Molecular Modeling ◽

Receptor Antagonist ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Its Analysis ◽

Structure Activity ◽

Relationship Of

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Molecular determinants for improved activity at PPARα: Structure–activity relationship of pirinixic acid derivatives, docking study and site-directed mutagenesis of PPARα

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2014.05.058 ◽

2014 ◽

Vol 24 (16) ◽

pp. 4048-4052 ◽

Cited By ~ 6

Author(s):

Christina Lamers ◽

Michaela Dittrich ◽

Ramona Steri ◽

Ewgenij Proschak ◽

Manfred Schubert-Zsilavecz

Keyword(s):

Docking Study ◽

Structure Activity Relationship ◽

Site Directed Mutagenesis ◽

Activity Relationship ◽

Directed Mutagenesis ◽

Structure Activity ◽

Molecular Determinants ◽

Relationship Of

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Structure–Activity Relationship of the Tyrosinase Inhibitors Kuwanon G, Mulberrofuran G, and Albanol B from Morus Species: A Kinetics and Molecular Docking Study

Molecules ◽

10.3390/molecules23061413 ◽

2018 ◽

Vol 23 (6) ◽

pp. 1413 ◽

Cited By ~ 9

Author(s):

Prashamsa Koirala ◽

Su Seong ◽

Yajuan Zhou ◽

Srijan Shrestha ◽

Hyun Jung ◽

...

Keyword(s):

Molecular Docking ◽

Docking Study ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Molecular Docking Study ◽

Structure Activity ◽

Tyrosinase Inhibitors ◽

Relationship Of

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Structure-activity relationship of [Nphe1 ]-NC-(1-13)-NH2 , a pure and selective nociceptin/orphanin FQ receptor antagonist

Journal of Peptide Research ◽

10.1111/j.1399-3011.2001.00820.x ◽

2001 ◽

Vol 57 (3) ◽

pp. 215-222 ◽

Cited By ~ 2

Author(s):

R. Guerrini ◽

S. Salvadori ◽

G. Calo' ◽

R. Bigoni ◽

D. Rizzi ◽

...

Keyword(s):

Receptor Antagonist ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Orphanin Fq ◽

Structure Activity ◽

Relationship Of

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Structure–activity relationship of [Nphe1]-NC-(1-13)-NH2, a pure and selective nociceptin/orphanin FQ receptor antagonist

Journal of Peptide Research ◽

10.1034/j.1399-3011.2001.057003215.x ◽

2001 ◽

Vol 57 (3) ◽

pp. 215-222

Author(s):

R. Guerrini ◽

S. Salvadori ◽

G. Calo' ◽

R. Bigoni ◽

D. Rizzi ◽

...

Keyword(s):

Receptor Antagonist ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Orphanin Fq ◽

Structure Activity ◽

Relationship Of

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C19-Steroids as androgen receptor modulators: Design, discovery, and structure-activity relationship of new steroidal androgen receptor antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2006.05.022 ◽

2006 ◽

Vol 14 (17) ◽

pp. 5933-5947 ◽

Cited By ~ 18

Author(s):

Padma Marwah ◽

Ashok Marwah ◽

Henry A. Lardy ◽

Hiroshi Miyamoto ◽

Chawnshang Chang

Keyword(s):

Androgen Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Receptor Antagonists ◽

Structure Activity ◽

Relationship Of ◽

Receptor Modulators ◽

Androgen Receptor Antagonists

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Studies of the New Herbicide KIH-6127. 4. Crystal Structure of KIH-6127 and Quantitative Structure−Activity Relationship of the Iminoxy Moiety of KIH-6127 Derivatives

Journal of Agricultural and Food Chemistry ◽

10.1021/jf960844v ◽

1997 ◽

Vol 45 (7) ◽

pp. 2777-2783 ◽

Cited By ~ 10

Author(s):

Masatoshi Tamaru ◽

Jun Inoue ◽

Ryo Hanai ◽

Shigehiko Tachikawa

Keyword(s):

Crystal Structure ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Of

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Structure-activity relationship of cytokinins: Crystal structure and conformation of 6-furfurylaminopurine (kinetin)

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(75)90155-2 ◽

1975 ◽

Vol 64 (3) ◽

pp. 1062-1068 ◽

Cited By ~ 17

Author(s):

M. Soriano-Garcia ◽

R. Parthasarathy

Keyword(s):

Crystal Structure ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of

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Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis

Planta Medica ◽

10.1055/s-0028-1084781 ◽

2008 ◽

Vol 74 (09) ◽

Author(s):

MA Brenzan ◽

CV Nakamura ◽

BPD Filho ◽

T Ueda-Nakamura ◽

MCM Young ◽

...

Keyword(s):

Structure Activity Relationship ◽

Leishmania Amazonensis ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of

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Structure Activity Relationship of Kahalalide F and its Analogs Against Fusarium Spp

Planta Medica ◽

10.1055/s-2008-1075262 ◽

2008 ◽

Vol 74 (03) ◽

Author(s):

N Kasanah ◽

AG Shilabin ◽

DE Wedge ◽

MT Hamann

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Fusarium Spp ◽

Structure Activity ◽

Kahalalide F ◽

Relationship Of

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