Long-term follow-up of syndromic craniosynostosis after Le Fort III halo distraction: A cephalometric and CT evaluation

2012 ◽  
Vol 65 (4) ◽  
pp. 464-472 ◽  
Author(s):  
Maria Costanza Meazzini ◽  
Fabiana Allevia ◽  
Fabio Mazzoleni ◽  
Luca Ferrari ◽  
Mario Pagnoni ◽  
...  
2004 ◽  
Vol 41 (6) ◽  
pp. 579-583 ◽  
Author(s):  
M. Emin Mavili ◽  
Gökhan Tunçbilek

Objective The traditional treatment for patients with syndromic craniosynostosis and midfacial retrusion has consisted of Le Fort III osteotomy and advancement. Distraction with rigid external systems allows advancement of the midface segment much more than the conventional methods. This excessive advancement resulted in the superiormost margin of the advancement segment becoming prominent. It can be felt easily with palpation and may influence the appearance of the patient negatively. This article presents a procedure osteotomy designed to modify the osteotomy lines at the lateral orbital rims and smooth the step deformity at the lateral canthal region. Results The seesaw osteotomy produced a smooth contour at the lateral orbital rim. Planned advancement was achieved without difficulty and without adverse long-term effects.


2018 ◽  
Vol 97 (10-11) ◽  
pp. E36-E43
Author(s):  
Vikram Shetty ◽  
Akshaya Kulkarni ◽  
Suman Banerjee

Rhinosporidiosis is a rare, chronic, granulomatous infection of the mucous membranes that mainly involves the nose and nasopharynx; it occasionally involves the pharynx, conjunctiva, larynx, trachea and, rarely, the skin. The characteristic clinical features of this disease include the formation of painless polyps in the nasal mucosa or the nasopharynx that bleed easily on touch. At our center, excision of the lesion with a Le Fort I osteotomy is carried out in patients (1) in whom two or more previous attempts at excision of biopsy-proven rhinosporidiosis arising from the nasal mucosa was carried out or (2) in whom the rhinosporidiosis arises from the nasophayrngeal mucosa and/or extranasal sites. In this article we retrospectively present 7 cases in which, according to our inclusion criteria, complete excision of the lesion was carried out with a Le Fort I osteotomy. Excellent visualization of the entire maxillary and ethmoidal air cells after the down-fracture of the maxilla helped in the total removal of the lesions. Most of these lesions had multiple points of origin through the nasal, maxillary, and ethmoidal mucosa; the excellent visualization enabled direct cauterization of all these points of origin. The mean follow-up period was 7.96 years, and all patients were disease-free by the time the study was prepared. This article presents details of the treatment protocol and technique followed at our center for the treatment of nasopharyngeal rhinosporidiosis and the details of long-term follow-up. Through this study we hope to prove the efficacy of Le Fort I osteotomy in the definitive management of nasopharyngeal rhinosporidiosis.


1988 ◽  
Vol 9 (10) ◽  
pp. 330-330

With increasing survival statistics in childhood acute lymphoblastic leukemia, long-term sequelae of therapy have become apparent. Prophylactic treatment of the CNS has significantly contributed to this improved survival. CNS prophylaxis has been done in a variety of ways. Cranial radiation therapy and intrathecal medication are used in some regimens, whereas intrathecal medicines plus systemic chemotherapy are used in others. The acute and late effects of cranial radiation are now being assessed by long-term follow-up of survivors of acute lymphoblastic leukemia. Neuropsychiatnic testing and computed tomography (CT) evaluation have been the parameters used in testing. CT findings, even as early as several months after irradiation, have included ventricular dilation, widening of subarachnoid spaces, areas of hypodensity, and intracerebral calcifications.


2014 ◽  
Vol 67 (2) ◽  
pp. e35-e41 ◽  
Author(s):  
Kazuaki Yamaguchi ◽  
Keisuke Imai ◽  
Takuya Fujimoto ◽  
Makoto Takahashi ◽  
Yoko Maruyama ◽  
...  

2004 ◽  
Vol 62 (8) ◽  
pp. 943-952 ◽  
Author(s):  
Scott D Urban ◽  
Joe Rebellato ◽  
Eugene E Keller

2020 ◽  
Vol 145 (4) ◽  
pp. 1025-1034 ◽  
Author(s):  
Cassio Eduardo Raposo-Amaral ◽  
Rafael Denadai ◽  
Guilherme Luis Zanco ◽  
Enrico Ghizoni ◽  
Cesar Augusto Raposo-Amaral

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.


Sign in / Sign up

Export Citation Format

Share Document