scholarly journals Characterization of a novel caudal vertebral interbody fusion in a rat tail model: An implication for future material and mechanical testing

2017 ◽  
Vol 40 (1) ◽  
pp. 62-68 ◽  
Author(s):  
Yu-Cheng Yeh ◽  
Cheng-Chun Yang ◽  
Ching-Lung Tai ◽  
Tsung-Ting Tsai ◽  
Po-Liang Lai ◽  
...  
Keyword(s):  
Mechanical Testing ◽  
Interbody Fusion ◽  
Rat Tail Model ◽  
Rat Tail

scholarly journals Effects of compressive loading on biomechanical properties of disc and peripheral tissue in a rat tail model

2009 ◽  
Vol 18 (11) ◽  
pp. 1595-1603 ◽  
Author(s):  
Tomokazu Nakamura ◽  
Takaro Iribe ◽  
Yoshinori Asou ◽  
Hiroo Miyairi ◽  
Kozo Ikegami ◽  
...  
Keyword(s):  
Compressive Loading ◽  
Biomechanical Properties ◽  
Peripheral Tissue ◽  
Rat Tail Model ◽  
Rat Tail

Characterization of ethylcellulose free films by positron annihilation spectroscopy and mechanical testing

2014 ◽  
Vol 115 ◽  
pp. 47-50 ◽  
Author(s):  
Diána Hegyesi ◽  
Károly Süvegh ◽  
András Kelemen ◽  
Klára Pintye-Hódi ◽  
Géza Regdon
Keyword(s):  
Positron Annihilation ◽  
Mechanical Testing ◽  
Positron Annihilation Spectroscopy ◽  
Free Films

Characteristics of ruminant mammary epithelial cells grown in primary culture in serum-free medium

1992 ◽  
Vol 59 (4) ◽  
pp. 491-498 ◽  
Author(s):  
Steven J. Winder ◽  
Alan Turvey ◽  
Isabel A. Forsyth
Keyword(s):  
Monoclonal Antibody ◽  
Mammary Epithelial Cells ◽  
Myoepithelial Cells ◽  
Mammary Epithelial ◽  
Serum Free ◽  
Commercial Medium ◽  
Attachment Factor ◽  
Rat Tail

SummaryCells were obtained from the mammary glands of sheep and cows by collagenase–hyaluronidase digestion. Characterization of cells as epithelial was by reaction with a monoclonal antibody to cytokeratin. A subpopulation of spindle-shaped or stellate cells reacted with a monoclonal antibody to desmin and may be related to myoepithelial cells. The development is described of a simple serum-free culture system for these cells on gels of rat tail (type 1) collagen. A commercial medium (M199) was used, buffered with Hepes and with bovine serum albumin as the sole protein supplement, plus fibronectin for the first 18 h only as an attachment factor. The cell cultures showed stimulated DNA synthesis in response to mitogens on attached gels and also responded as floating cultures to lactogenic hormones with production of α-lactalbumin.

An investigation on the biodynamic foundation of a rat tail vibration model

2008 ◽  
Vol 222 (7) ◽  
pp. 1127-1141 ◽  
Author(s):  
D E Welcome ◽  
K Krajnak ◽  
M L Kashon ◽  
R G Dong
Keyword(s):  
Equivalent Model ◽  
Laser Vibrometer ◽  
Mechanical Equivalent ◽  
Biological Responses ◽  
Vibration Model ◽  
Reasonable Approach ◽  
Human Finger ◽  
Rat Tail Model ◽  
Measurement Location ◽  
Rat Tail

The objectives of this study are to examine the fundamental characteristics of the biodynamic responses of a rat tail to vibration and to compare them with those of human fingers. Vibration transmission through tails exposed to three vibration magnitudes (1 g, 5 g, and 10 g r.m.s.) at six frequencies (32 Hz, 63 Hz, 125 Hz, 160 Hz, 250 Hz, and 500 Hz) was measured using a laser vibrometer. A mechanical-equivalent model of the tail was established on the basis of the transmissibility data, which was used to estimate the biodynamic deformation and vibration power absorption at several representative locations on the tail. They were compared with those derived from a mechanical-equivalent model of human fingers reported in the literature. This study found that, similar to human fingers, the biodynamic responses of the rat tail depends on the vibration magnitude, frequency, and measurement location. With the restraint method used in this study, the natural frequency of the rat tail is in the range 161–368 Hz, which is mostly within the general range of human finger resonant frequencies (100–350 Hz). However, the damping ratios of the rat tail at the unconstrained locations are from 0.094 to 0.394, which are lower than those of human fingers (0.708–0.725). Whereas the biodynamic responses of human fingers at frequencies lower than 100 Hz could be significantly influenced by the biodynamics of the entire hand—arm system, the rat tail biodynamic responses can be considered independent of the rat body in the frequency range used in this study. Based on these findings it is concluded that, although there are some differences between the frequency dependences of the biodynamic responses of the rat tail and human fingers, the rat tail model can provide a practical and reasonable approach to examine the relationships between the biodynamic and biological responses at midrange to high frequencies, and to understand the mechanisms underlying vibration-induced finger disorders.

Vibration from a riveting hammer causes severe nerve damage in the rat tail model

2011 ◽  
Vol 44 (5) ◽  
pp. 795-804 ◽  
Author(s):  
Sandya Govinda Raju ◽  
Olaf Rogness ◽  
Magnus Persson ◽  
James Bain ◽  
Danny Riley
Keyword(s):  
Nerve Damage ◽  
Rat Tail Model ◽  
Rat Tail

Progression of Vertebral Wedging in an Asymmetrically Loaded Rat Tail Model

Spine ◽  
1997 ◽  
Vol 22 (12) ◽  
pp. 1292-1296 ◽  
Author(s):  
Peter L. Mente ◽  
lan A. F. Stokes ◽  
Holly Spence ◽  
David D. Aronsson
Keyword(s):  
Rat Tail Model ◽  
Vertebral Wedging ◽  
Rat Tail

Endothelial Cell Injury Under High Frequency Vibration in the Rat-Tail Model

2011 ◽  
Author(s):  
Shilpi Goenka ◽  
Srikara V. Peelukhana ◽  
Jay Kim ◽  
Keith F. Stringer ◽  
Rupak K. Banerjee
Keyword(s):  
Endothelial Cells ◽  
Endothelial Cell ◽  
Oxidative Damage ◽  
Cell Injury ◽  
Industrial Workers ◽  
Injury Model ◽  
Blue Stain ◽  
Hematoxylin And Eosin ◽  
Rat Tail Model ◽  
Rat Tail

Hand-Arm Vibration Syndrome (HAVS) consists of vascular, sensorineural and musculoskeletal disorders and affects around 1.7–5.8% of industrial workers. In this study, a rat-tail vibration injury model is used to assess early vascular damage due to HAVS, manifested in the form of endothelial cell vacuolation and oxidative injury. Tails were vibrated at two frequencies 125Hz and 250Hz for 4hr/day for 1 and 5 days (49m/s2). Hematoxylin and Eosin (H&E) staining was done to assess gross changes in artery sections and toluidine blue stain was done for vacuole counting. Immunohistochemical (IHC) methods were used to detect Nitrotyrosine, a potent biomarker of cell inflammation and oxidative stress. The vacuole count in Endothelial Cells (ECs) was not statistically significant after 1 and 5 days for any frequency. However IHC images showed significant oxidative damage in Endothelial Cells (ECs) with considerable oxidative damage being induced as early as 1 day for both 125Hz and 250Hz frequencies, with more EC damage induced by 250Hz frequency after 5 days. These findings indicate that higher frequency vibrations can cause severe oxidative damage to EC.

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