Construction of a highly sensitive non-enzymatic sensor for superoxide anion radical detection from living cells

2017 ◽  
Vol 90 ◽  
pp. 39-45 ◽  
Author(s):  
Yuelin Liu ◽  
Xiuhui Liu ◽  
Yidan Liu ◽  
Guoan Liu ◽  
Lan Ding ◽  
...  
Keyword(s):  
Superoxide Anion ◽  
Anion Radical ◽  
Living Cells ◽  
Superoxide Anion Radical ◽  
Enzymatic Sensor ◽  
Highly Sensitive ◽  
Radical Detection

A highly selective and sensitive nanoprobe for detection and imaging of the superoxide anion radical in living cells

2012 ◽  
Vol 48 (19) ◽  
pp. 2507 ◽  
Author(s):  
Na Li ◽  
Hui Wang ◽  
Mei Xue ◽  
Chenyang Chang ◽  
Zhenzhen Chen ◽  
...  
Keyword(s):  
Superoxide Anion ◽  
Anion Radical ◽  
Living Cells ◽  
Superoxide Anion Radical

A sensitively non-enzymatic amperometric sensor and its application in living cell superoxide anion radical detection

Talanta ◽  
2018 ◽  
Vol 186 ◽  
pp. 248-255 ◽  
Author(s):  
Xinhe Liu ◽  
Miaomiao Ran ◽  
Guoan Liu ◽  
Xiuhui Liu ◽  
Zhonghua Xue ◽  
...  
Keyword(s):  
Superoxide Anion ◽  
Living Cell ◽  
Anion Radical ◽  
Superoxide Anion Radical ◽  
Amperometric Sensor ◽  
Radical Detection

Superoxide Anion Radical: Generation and Detection in Cellular and Non-Cellular Systems

2015 ◽  
Vol 22 (37) ◽  
pp. 4234-4256 ◽  
Author(s):  
Renan Chiste ◽  
Marisa Freitas ◽  
Adriana Mercadante ◽  
Eduarda Fernandes
Keyword(s):  
Superoxide Anion ◽  
Anion Radical ◽  
Cellular Systems ◽  
Superoxide Anion Radical ◽  
Radical Generation

scholarly journals Effect of extraction conditions of paprika oleoresins on their free radical scavenging and anticancer activity

2014 ◽  
Vol 12 (3) ◽  
pp. 377-385 ◽  
Author(s):  
Vesna Šaponjac ◽  
Dragana Četojević-Simin ◽  
Gordana Ćetković ◽  
Jasna Čanadanović-Brunet ◽  
Sonja Djilas ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Cell Line ◽  
Antiproliferative Activity ◽  
Superoxide Anion ◽  
Anion Radical ◽  
Radical Scavenging ◽  
Superoxide Anion Radical ◽  
Food Ingredients ◽  
Supercritical Carbon

AbstractGround spice paprika was extracted with hexane, by conventional Soxhlet procedure (SX oleoresin), and with supercritical carbon dioxide at three different pressures — 20, 30 and 40 MPa (SF20, SF30 and SF40 oleoresins). The effect of extraction method and conditions on the colour intesity of paprika oleoresins, content of α-tocopherol, as well as antioxidant and antiproliferative activity was examined. Hexane showed highest selectivity for paprika pigments (886.02 ASTA), while α-tocopherol showed highest solubility (3846.9 mg kg−1) in supercritical carbon dioxide at 20 MPa. All paprika oleoresins exhibited good superoxide anion radical scavenging activity SF30 being the best superoxide anion radical scavenger. Cell growth activity was evaluated in vitro in human cell lines:cervix epitheloid carcinoma (HeLa), breast adenocarcinoma (MCF7) and colon adenocarcinoma (HT-29). The highest antiproliferative activity was exhibited by SX in MCF7 cell line (IC50=14.28 mg mL−1). Extract SF40 produced significant and selective antiproliferative action towards HeLa cell line. These results suggest that paprika oleoresins, due to high antiradical and tumor cell-inhibiting activity, can be regarded as functional food ingredients.

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