A label-free colorimetric aptasensor for simple, sensitive and selective detection of Pt (II) based on platinum (II)-oligonucleotide coordination induced gold nanoparticles aggregation

2016 ◽  
Vol 85 ◽  
pp. 771-776 ◽  
Author(s):  
Daoqing Fan ◽  
Qingfeng Zhai ◽  
Weijun Zhou ◽  
Xiaoqing Zhu ◽  
Erkang Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Selective Detection ◽  
Label Free ◽  
Colorimetric Aptasensor

A gold nanoparticle-based label free colorimetric aptasensor for adenosine deaminase detection and inhibition assay

The Analyst ◽  
2015 ◽  
Vol 140 (5) ◽  
pp. 1572-1577 ◽  
Author(s):  
Fen Cheng ◽  
Yue He ◽  
Xiao-Jing Xing ◽  
Dai-Di Tan ◽  
Yi Lin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Adenosine Deaminase ◽  
Gold Nanoparticle ◽  
Label Free ◽  
Inhibition Assay ◽  
Free Gold ◽  
Novel Strategy ◽  
Colorimetric Aptasensor

A novel strategy for the fabrication of a colorimetric aptasensor using label free gold nanoparticles (AuNPs) is proposed. The aptasensor consists of adenosine (AD) aptamer, AD and AuNPs. The strategy has been employed for the assay of adenosine deaminase (ADA) activity.

A facile label-free colorimetric aptasensor for ricin based on the peroxidase-like activity of gold nanoparticles

RSC Advances ◽  
2015 ◽  
Vol 5 (21) ◽  
pp. 16036-16041 ◽  
Author(s):  
Jingting Hu ◽  
Pengjuan Ni ◽  
Haichao Dai ◽  
Yujing Sun ◽  
Yilin Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Label Free ◽  
First Time ◽  
Colorimetric Aptasensor

A facile colorimetric aptasensor for ricin based on the peroxidase-like activity of gold nanoparticles was demonstrated for the first time.

Label-free colorimetric aptasensor for highly sensitive and selective detection of proteins by using PNA/DNA hybrids and a cyanine dye

2018 ◽  
Vol 10 (31) ◽  
pp. 3824-3829 ◽  
Author(s):  
Mengjia Xu ◽  
Shu Xing ◽  
Xiaojun Xu ◽  
Pan Fu ◽  
Wanxing Xu ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Cyanine Dye ◽  
Selective Detection ◽  
Label Free ◽  
Highly Sensitive ◽  
Colorimetric Aptasensor

A label-free colorimetric aptasensor that uses PNA/DNA hybrids and a cyanine dye (DiSC2(5)) was developed for highly sensitive and selective detection of proteins in aqueous solution.

scholarly journals Experimental and theoretical approaches for the selective detection of thymine in real samples using gold nanoparticles as a biochemical sensor

RSC Advances ◽  
2018 ◽  
Vol 8 (43) ◽  
pp. 24328-24337 ◽  
Author(s):  
Kamlesh Shrivas ◽  
Nidhi Nirmalkar ◽  
Santosh Singh Thakur ◽  
Ramsingh Kurrey ◽  
Deepak Sinha ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cost Effective ◽  
Selective Detection ◽  
Label Free ◽  
Real Samples ◽  
Qualitative And Quantitative ◽  
Biochemical Sensor ◽  
Theoretical Approaches ◽  
Cost Effective Method

We report a simple, selective and cost effective method for the qualitative and quantitative determination of thymine in a DNA standard and in urine samples using gold nanoparticles (AuNPs) as a label-free colorimetric biochemical sensor.

scholarly journals Ultrasensitive and label free electrochemical immunosensor for detection of ROR1 as an oncofetal biomarker using gold nanoparticles assisted LDH/rGO nanocomposite

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rozita Abolhasan ◽  
Balal Khalilzadeh ◽  
Hadi Yousefi ◽  
Sahar Samemaleki ◽  
Forough Chakari-Khiavi ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Flexible Structures ◽  
Modified Electrodes ◽  
Electrochemical Immunosensor ◽  
Lymphocytic Leukemia ◽  
Orphan Receptor ◽  
Detection Sensitivity ◽  
Label Free ◽  
Serum Samples ◽  
Limit Of Quantification

AbstractIn the present article, we developed a highly sensitive label-free electrochemical immunosensor based on NiFe-layered double hydroxides (LDH)/reduced graphene oxide (rGO)/gold nanoparticles modified glassy carbon electrode for the determination of receptor tyrosine kinase-like orphan receptor (ROR)-1. In this electrochemical immunoassay platform, NiFe-LDH/rGO was used due to great electron mobility, high specific surface area and flexible structures, while Au nanoparticles were prepared and coated on the modified electrodes to improve the detection sensitivity and ROR1 antibody immobilizing (ROR1Ab). The modification procedure was approved by using cyclic voltammetry and differential pulse voltammetry based on the response of peak current to the step by step modifications. Under optimum conditions, the experimental results showed that the immunosensor revealed a sensitive response to ROR1 in the range of 0.01–1 pg mL−1, and with a lower limit of quantification of 10 attogram/mL (10 ag mL−1). Furthermore, the designed immunosensor was applied for the analysis of ROR1 in several serum samples of chronic lymphocytic leukemia suffering patients with acceptable results, and it also exhibited good selectivity, reproducibility and stability.

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