Real-time, in situ DNA hybridization detection with attomolar sensitivity without amplification using (pb(Mg1/3Nb2/3)O3)0.65–(PbTiO3)0.35 piezoelectric plate sensors

2013 ◽  
Vol 43 ◽  
pp. 391-399 ◽  
Author(s):  
Wei Wu ◽  
Ceyhun E Kirimli ◽  
Wei-Heng Shih ◽  
Wan Y. Shih
Keyword(s):  
Real Time ◽  
Dna Hybridization ◽  
Piezoelectric Plate ◽  
Hybridization Detection

scholarly journals In-situ DNA hybridization detection with a reflective microfiber grating biosensor

2014 ◽  
Vol 61 ◽  
pp. 541-546 ◽  
Author(s):  
Dandan Sun ◽  
Tuan Guo ◽  
Yang Ran ◽  
Yunyun Huang ◽  
Bai-Ou Guan
Keyword(s):  
Dna Hybridization ◽  
Hybridization Detection

scholarly journals DNA hybridization detection with 100 zM sensitivity using piezoelectric plate sensors with an improved noise-reduction algorithm

The Analyst ◽  
2014 ◽  
Vol 139 (11) ◽  
pp. 2754-2763 ◽  
Author(s):  
Ceyhun E. Kirimli ◽  
Wei-Heng Shih ◽  
Wan Y. Shih
Keyword(s):  
Piezoelectric Plate ◽  
Peak Position ◽  
Lead Magnesium Niobate ◽  
Buffer Solution ◽  
Target Dna ◽  
Fitting Algorithm ◽  
Lead Magnesium ◽  
Thick Lead ◽  
Hybridization Detection

We have examined real-time,in situhybridization detection of target DNA (tDNA) in a buffer solution and in urine using 8 μm-thick lead magnesium niobate–lead titanate (PMN–PT) piezoelectric plate sensors (PEPSs) with improved 3-mercaptopropyltrimethoxysilane (MPS) insulation and a new multiple-parabola (>50) resonance peak position fitting algorithm.

scholarly journals Resolution-improved in situ DNA hybridization detection based on microwave photonic interrogation

2015 ◽  
Vol 23 (21) ◽  
pp. 27061 ◽  
Author(s):  
Yuan Cao ◽  
Tuan Guo ◽  
Xudong Wang ◽  
Dandan Sun ◽  
Yang Ran ◽  
...  
Keyword(s):  
Dna Hybridization ◽  
Microwave Photonic ◽  
Hybridization Detection

In-situ ultrasensitive label-free DNA hybridization detection using optical fiber specklegram

2018 ◽  
Vol 272 ◽  
pp. 160-165 ◽  
Author(s):  
Fu Feng ◽  
Wang Chen ◽  
Dihan Chen ◽  
Wei Lin ◽  
Shih-Chi Chen
Keyword(s):  
Optical Fiber ◽  
Dna Hybridization ◽  
Label Free ◽  
Free Dna ◽  
Hybridization Detection

scholarly journals In-situ DNA hybridization detection based on a reflective microfiber probe

2020 ◽  
Vol 28 (2) ◽  
pp. 970
Author(s):  
Yanpeng Li ◽  
Fang Fang ◽  
Liuyang Yang ◽  
ShiJie Tan ◽  
Zhijun Yan ◽  
...  
Keyword(s):  
Dna Hybridization ◽  
Hybridization Detection

Probing the Dynamic Self-Assembly Behaviour of Photoswitchable Wormlike Micelles in Real Time

2018 ◽  
Author(s):  
Elaine A. Kelly ◽  
Judith E. Houston ◽  
Rachel Evans
Keyword(s):  
Real Time ◽  
Absorption Spectroscopy ◽  
Self Assembly ◽  
Uv Light ◽  
Wormlike Micelles ◽  
Tetraethylene Glycol ◽  
Light Illumination ◽  
First Time ◽  
Dependent Processes

Understanding the dynamic self-assembly behaviour of azobenzene photosurfactants (AzoPS) is crucial to advance their use in controlled release applications such as<i></i>drug delivery and micellar catalysis. Currently, their behaviour in the equilibrium <i>cis-</i>and <i>trans</i>-photostationary states is more widely understood than during the photoisomerisation process itself. Here, we investigate the time-dependent self-assembly of the different photoisomers of a model neutral AzoPS, <a>tetraethylene glycol mono(4′,4-octyloxy,octyl-azobenzene) </a>(C<sub>8</sub>AzoOC<sub>8</sub>E<sub>4</sub>) using small-angle neutron scattering (SANS). We show that the incorporation of <i>in-situ</i>UV-Vis absorption spectroscopy with SANS allows the scattering profile, and hence micelle shape, to be correlated with the extent of photoisomerisation in real-time. It was observed that C<sub>8</sub>AzoOC<sub>8</sub>E<sub>4</sub>could switch between wormlike micelles (<i>trans</i>native state) and fractal aggregates (under UV light), with changes in the self-assembled structure arising concurrently with changes in the absorption spectrum. Wormlike micelles could be recovered within 60 seconds of blue light illumination. To the best of our knowledge, this is the first time the degree of AzoPS photoisomerisation has been tracked <i>in</i><i>-situ</i>through combined UV-Vis absorption spectroscopy-SANS measurements. This technique could be widely used to gain mechanistic and kinetic insights into light-dependent processes that are reliant on self-assembly.

Flat Flexible Thin Milli-electrode Array for Real-time in situ Water Quality Monitoring in Distribution Systems

2017 ◽  
Vol 2017 (4) ◽  
pp. 5598-5617
Author(s):  
Zhiheng Xu ◽  
Wangchi Zhou ◽  
Qiuchen Dong ◽  
Yan Li ◽  
Dingyi Cai ◽  
...  
Keyword(s):  
Water Quality ◽  
Real Time ◽  
Distribution Systems ◽  
Electrode Array ◽  
Water Quality Monitoring ◽  
Quality Monitoring

A new method for the in situ assay of α-glucosidase activity and inhibitor screening through an enzyme substrate-mediated DNA hybridization chain reaction

2019 ◽  
Vol 43 (24) ◽  
pp. 9458-9465
Author(s):  
Xiquan Yue ◽  
Lihong Su ◽  
Xu Chen ◽  
Junfeng Liu ◽  
Longpo Zheng ◽  
...  
Keyword(s):  
Small Molecule ◽  
Dna Hybridization ◽  
New Method ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Inhibitor Screening ◽  
Glucosidase Activity ◽  
Enzyme Substrate ◽  
In Situ Assay

The strategy is based on small molecule-mediated hybridization chain reaction.

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