Label-free, nucleotide-mediated dispersion of magnetic nanoparticles for “non-sandwich type” MRI-based quantification of enzyme

2013 ◽  
Vol 41 ◽  
pp. 78-83 ◽  
Author(s):  
Guohai Liang ◽  
Lifu Xiao ◽  
Hui Chen ◽  
Qian Liu ◽  
Song Zhang ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Label Free ◽  
Free Nucleotide ◽  
Sandwich Type

Electrochemical Immunosensors Based on Nanostructured Materials for Sensing of Prostate-Specific Antigen: A Review

2020 ◽  
Vol 28 ◽  
Author(s):  
Hayati Filik ◽  
Asiye Aslıhan Avan ◽  
Mustafa Özyürek
Keyword(s):  
Prostate Specific Antigen ◽  
Nanostructured Materials ◽  
Specific Antigen ◽  
Electrochemical Immunosensor ◽  
Label Free ◽  
Electrochemical Immunosensors ◽  
Metal Metal ◽  
Different Types ◽  
Sandwich Type ◽  
Carbon Based Nanomaterials

: The prostate-specific antigen (PSA) has been considered a crucial serological marker for distinguishing prostate based cancer. This surveys recent progress in the construction of nanomaterial-based electrochemical immunosensors for a PSA. This review (from 2015 to 2020) reports the latest progress in PSA sensing based on the employ of different types of nanostructured materials. The most popular used nanostructured materials are metal, metal oxide, carbon-based nanomaterials, and their hybrid architectures utilized for distinct amplification protocols. In this review, the electrochemical immunosensors for prostate-specific antigen sensing are classified into three categories such as sandwich type@labeled, label free@nonlabeled and aptamer-based electrochemical immunosensor.

scholarly journals Volumetric registration of magnetic nanoparticles for optimization of quantitative immunochromatographic assays for detection of small molecules

2018 ◽  
Vol 185 ◽  
pp. 10006 ◽  
Author(s):  
Natalia V. Guteneva ◽  
Sergey L. Znoyko ◽  
Alexey V. Orlov ◽  
Maxim P. Nikitin ◽  
Petr I. Nikitin
Keyword(s):  
Magnetic Nanoparticles ◽  
Small Molecules ◽  
Optical Methods ◽  
Magnetic Method ◽  
Label Free ◽  
Spectral Correlation ◽  
Entire Volume ◽  
Specificity And Sensitivity ◽  
Particle Quantification

Precise quantitative and highly sensitive detection of small molecules (haptens) is highly demanded in medicine, food quality control, in vitro diagnostics, criminalistics, environmental monitoring, etc. In the present work, the magnetic method of particle quantification and the optical methods of spectral correlation and spectral phase interferometry complement each other for optimization of a quantitative assay for measuring concentrations of small molecules. The assay employs magnetic nanoparticles as labels in rapid immunochromatographic format. The approach was demonstrated with fluorescein as a model molecule. The interferometric label-free biosensors were employed for selection of optimal reagents that produced high specificity and sensitivity. The method of magnetic particle quantification counted the magnetic labels over the entire volume of the immunochromatographic membrane to provide their distribution along the test strip. Such distribution was used for optimization of such parameters as concentrations of the used reagents and of antibody immobilized on the labels, amount of the labels and conjugates of haptens with protein carriers to realize the advanced quantitative immunochromatographic assay.

scholarly journals Indirect magnetic force microscopy

2019 ◽  
Vol 1 (6) ◽  
pp. 2348-2355 ◽  
Author(s):  
Joshua Sifford ◽  
Kevin J. Walsh ◽  
Sheng Tong ◽  
Gang Bao ◽  
Gunjan Agarwal
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Force Microscopy ◽  
Magnetic Force ◽  
Label Free ◽  
Force Microscopy ◽  
Novel Approach

Indirect magnetic force microscopy (ID-MFM): a novel approach to detect magnetic nanoparticles in a multimodal, label-free manner.

Yolk–shell nanostructured Fe3O4@C magnetic nanoparticles with enhanced peroxidase-like activity for label-free colorimetric detection of H2O2and glucose

Nanoscale ◽  
2017 ◽  
Vol 9 (13) ◽  
pp. 4508-4515 ◽  
Author(s):  
Na Lu ◽  
Min Zhang ◽  
Lei Ding ◽  
Jing Zheng ◽  
Caixia Zeng ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Colorimetric Detection ◽  
Label Free

Label-free protein quantification after ultrafast digestion of complex proteomes using ultrasonic energy and immobilized-trypsin magnetic nanoparticles

Talanta ◽  
2019 ◽  
Vol 196 ◽  
pp. 262-270 ◽  
Author(s):  
Gonçalo Martins ◽  
Javier Fernández-Lodeiro ◽  
Jamila Djafari ◽  
Carlos Lodeiro ◽  
J.L. Capelo ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Protein Quantification ◽  
Ultrasonic Energy ◽  
Label Free ◽  
Free Protein ◽  
Immobilized Trypsin
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