Novel electrical detection of label-free disease marker proteins using piezoresistive self-sensing micro-cantilevers

2005 ◽  
Vol 20 (10) ◽  
pp. 1932-1938 ◽  
Author(s):  
Kyung Wook Wee ◽  
Ghi Yuun Kang ◽  
Jaebum Park ◽  
Ji Yoon Kang ◽  
Dae Sung Yoon ◽  
...  
Keyword(s):  
Label Free ◽  
Electrical Detection ◽  
Disease Marker ◽  
Marker Proteins

Label-free electrical detection of DNA by means of field-effect nanoplate capacitors: Experiments and modeling

2012 ◽  
Vol 209 (5) ◽  
pp. 925-934 ◽  
Author(s):  
Maryam H. Abouzar ◽  
Arshak Poghossian ◽  
Andrey G. Cherstvy ◽  
Angela M. Pedraza ◽  
Sven Ingebrandt ◽  
...  
Keyword(s):  
Field Effect ◽  
Label Free ◽  
Electrical Detection

Label-Free Electrical Detection of DNA Hybridization on Graphene using Hall Effect Measurements: Revisiting the Sensing Mechanism

2013 ◽  
Vol 23 (18) ◽  
pp. 2301-2307 ◽  
Author(s):  
Cheng-Te Lin ◽  
Phan Thi Kim Loan ◽  
Tzu-Yin Chen ◽  
Keng-Ku Liu ◽  
Chang-Hsiao Chen ◽  
...  
Keyword(s):  
Hall Effect ◽  
Dna Hybridization ◽  
Label Free ◽  
Electrical Detection ◽  
Sensing Mechanism ◽  
Hall Effect Measurements

A Dual-Gate Field-Effect Transistor for Label-Free Electrical Detection of Avian Influenza

2012 ◽  
Vol 2 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Jee-Yeon Kim ◽  
Jae-Hyuk Ahn ◽  
Dong-Il Moon ◽  
Sungho Kim ◽  
Tae Jung Park ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Label Free ◽  
Electrical Detection ◽  
Dual Gate ◽  
Effect Transistor

Monitoring Amyloid Sup35NM Growth with Label-Free Electrical Detection Using a Field-Effect Transistor Biosensor

2013 ◽  
Vol 1 (1) ◽  
pp. 51-54 ◽  
Author(s):  
Sho Hideshima ◽  
Shofarul Wustoni ◽  
Shigeki Kuroiwa ◽  
Takuya Nakanishi ◽  
Ayumi Koike-Takeshita ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Label Free ◽  
Electrical Detection ◽  
Effect Transistor

Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips

2014 ◽  
Vol 211 (6) ◽  
pp. 1423-1428 ◽  
Author(s):  
Chunsheng Wu ◽  
Thomas Bronder ◽  
Arshak Poghossian ◽  
Carl Frederik Werner ◽  
Matthias Bäcker ◽  
...  
Keyword(s):  
Label Free ◽  
Electrical Detection ◽  
Dna Chips

Single-Molecule Electrical Detection with Real-Time Label-Free Capability and Ultrasensitivity

Small Methods ◽  
2017 ◽  
Vol 1 (5) ◽  
pp. 1700071 ◽  
Author(s):  
Chunhui Gu ◽  
Chuancheng Jia ◽  
Xuefeng Guo
Keyword(s):  
Real Time ◽  
Single Molecule ◽  
Label Free ◽  
Electrical Detection

scholarly journals Rapid Quantification of Disease-Marker Proteins Using Continuous-Flow Immunoseparation in a Nanosieve Fluidic Device

2009 ◽  
Vol 81 (16) ◽  
pp. 7067-7074 ◽  
Author(s):  
Masumi Yamada ◽  
Pan Mao ◽  
Jianping Fu ◽  
Jongyoon Han
Keyword(s):  
Continuous Flow ◽  
Disease Marker ◽  
Marker Proteins ◽  
Fluidic Device ◽  
Rapid Quantification

Electrical Detection of Protein Biomarkers Using Nanoneedle Biosensors

2012 ◽  
Vol 1414 ◽  
Author(s):  
Rahim Esfandyarpour ◽  
Hesaam Esfandyarpour ◽  
Mehdi Javanmard ◽  
James S. Harris ◽  
Ronald W. Davis
Keyword(s):  
Physical Adsorption ◽  
Ionic Current ◽  
Microfluidic Channel ◽  
Protein Detection ◽  
High Sensitivity ◽  
Receptor Protein ◽  
Label Free ◽  
Electrical Detection ◽  
Protein Biomarkers ◽  
Impedance Modulation

Abstract:Here we present the development of an array of electrical nano-biosensors in a microfluidic channel, called Nanoneedle biosensors. Then we present the proof of concept study for protein detection. A Nanoneedle biosensor is a real-time, label-free, direct electrical detection platform, which is capable of high sensitivity detection, measuring the change in ionic current and impedance modulation, due to the presence or reaction of biomolecules such as proteins or nucleic acids. We show that the sensors which have been fabricated and characterized for the protein detection. We have functionalized Nanoneedle biosensors with receptors specific to a target protein using physical adsorption for immobilization. We have used biotinylated bovine serum albumin as the receptor and sterptavidin as the target analyte. The detection of streptavidin binding to the receptor protein is also presented.

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