Identification of retinoblastoma related genes with shortest path in a protein–protein interaction network

Biochimie ◽  
2012 ◽  
Vol 94 (9) ◽  
pp. 1910-1917 ◽  
Author(s):  
Bi-Qing Li ◽  
Jian Zhang ◽  
Tao Huang ◽  
Lei Zhang ◽  
Yu-Dong Cai
Keyword(s):  
Shortest Path ◽  
Protein Interaction ◽  
Protein Interaction Network ◽  
Interaction Network ◽  
Protein Protein Interaction ◽  
Protein Protein Interaction Network

scholarly journals Identifying Gastric Cancer Related Genes Using the Shortest Path Algorithm and Protein-Protein Interaction Network

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Yang Jiang ◽  
Yang Shu ◽  
Ying Shi ◽  
Li-Peng Li ◽  
Fei Yuan ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Shortest Path ◽  
Protein Interaction ◽  
Protein Interaction Network ◽  
High Probability ◽  
Biological Process ◽  
Interaction Network ◽  
Shortest Path Algorithm ◽  
Protein Protein Interaction ◽  
Protein Protein Interaction Network

Gastric cancer, as one of the leading causes of cancer related deaths worldwide, causes about 800,000 deaths per year. Up to now, the mechanism underlying this disease is still not totally uncovered. Identification of related genes of this disease is an important step which can help to understand the mechanism underlying this disease, thereby designing effective treatments. In this study, some novel gastric cancer related genes were discovered based on the knowledge of known gastric cancer related ones. These genes were searched by applying the shortest path algorithm in protein-protein interaction network. The analysis results suggest that some of them are indeed involved in the biological process of gastric cancer, which indicates that they are the actual gastric cancer related genes with high probability. It is hopeful that the findings in this study may help promote the study of this disease and the methods can provide new insights to study various diseases.

scholarly journals Diabetic Retinopathy and Laser Therapy in Rats: A Protein-Protein Interaction Network Analysis

2017 ◽  
Vol 8 (Suppl 1) ◽  
pp. S20-S21 ◽  
Author(s):  
Akram Safaei ◽  
Mostafa Rezaei Tavirani ◽  
Mona Zamanian Azodi ◽  
Alireza Lashay ◽  
Seyed Farzad Mohammadi ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Network Analysis ◽  
Laser Therapy ◽  
Protein Interaction ◽  
Protein Interaction Network ◽  
Interaction Network ◽  
Protein Protein Interaction ◽  
Protein Protein Interaction Network
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