Corrigendum to ‘Mitofusin 2 ameliorates hypoxia-induced apoptosis via mitochondrial function and signaling pathways title of article’ [International Journal of Biochemistry and Cell Biology 69 (2015) 29–40]

2016 ◽  
Vol 73 ◽  
pp. 137
Author(s):  
Cheng Peng ◽  
Wei Rao ◽  
Lei Zhang ◽  
Kai Wang ◽  
Hao Hui ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Mitochondrial Function ◽  
Cell Biology ◽  
Mitofusin 2 ◽  
Induced Apoptosis

scholarly journals Activation of MST/Krs and c-Jun N-terminal Kinases by Different Signaling Pathways during Cytotrienin A-induced Apoptosis

2000 ◽  
Vol 275 (12) ◽  
pp. 8766-8771 ◽  
Author(s):  
Masahiko Watabe ◽  
Hideaki Kakeya ◽  
Rie Onose ◽  
Hiroyuki Osada
Keyword(s):  
Signaling Pathways ◽  
Induced Apoptosis

scholarly journals Adenosine Triphosphate Prevents Serum Deprivation-Induced Apoptosis in Human Mesenchymal Stem Cells via Activation of the MAPK Signaling Pathways

Stem Cells ◽  
2014 ◽  
Vol 33 (1) ◽  
pp. 211-218 ◽  
Author(s):  
Jessica L. Berlier ◽  
Sabrina Rigutto ◽  
Antoine Dalla Valle ◽  
Jessica Lechanteur ◽  
Muhammad S. Soyfoo ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Signaling Pathways ◽  
Adenosine Triphosphate ◽  
Human Mesenchymal Stem Cells ◽  
Mapk Signaling ◽  
Serum Deprivation ◽  
Induced Apoptosis ◽  
Mapk Signaling Pathways

scholarly journals Clinical significance of mitofusin-2 and its signaling pathways in hepatocellular carcinoma

2016 ◽  
Vol 14 (1) ◽  
Author(s):  
Yingsheng Wu ◽  
Dongkai Zhou ◽  
Xiaobo Xu ◽  
Xinyi Zhao ◽  
Pengfei Huang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Signaling Pathways ◽  
Clinical Significance ◽  
Mitofusin 2

scholarly journals Inhibitory of EV-A71 virus-induced apoptosis by ZVAD through ROS mediated signaling pathways

BIOCELL ◽  
2022 ◽  
Vol 46 (4) ◽  
pp. 1033-1039
Author(s):  
TIANTIAN XU ◽  
RUILIN ZHENG ◽  
DANYANG CHEN ◽  
HAIYANG CHEN ◽  
MINGQI ZHAO ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Induced Apoptosis

scholarly journals Understanding MAPK Signaling Pathways in Apoptosis

2020 ◽  
Vol 21 (7) ◽  
pp. 2346 ◽  
Author(s):  
Jicheng Yue ◽  
José M. López
Keyword(s):  
Signaling Pathways ◽  
Positive Feedback ◽  
Cell Model ◽  
Mapk Signaling ◽  
Feedback Loops ◽  
Mitogen Activated Protein Kinase ◽  
Cellular Mechanisms ◽  
Mitogen Activated Protein ◽  
Induced Apoptosis ◽  
Mapk Signaling Pathways

MAPK (mitogen-activated protein kinase) signaling pathways regulate a variety of biological processes through multiple cellular mechanisms. In most of these processes, such as apoptosis, MAPKs have a dual role since they can act as activators or inhibitors, depending on the cell type and the stimulus. In this review, we present the main pro- and anti-apoptotic mechanisms regulated by MAPKs, as well as the crosstalk observed between some MAPKs. We also describe the basic signaling properties of MAPKs (ultrasensitivity, hysteresis, digital response), and the presence of different positive feedback loops in apoptosis. We provide a simple guide to predict MAPKs’ behavior, based on the intensity and duration of the stimulus. Finally, we consider the role of MAPKs in osmostress-induced apoptosis by using Xenopus oocytes as a cell model. As we will see, apoptosis is plagued with multiple positive feedback loops. We hope this review will help to understand how MAPK signaling pathways engage irreversible cellular decisions.

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