Stereospecific reduction of a potent kinesin spindle protein (KSP) inhibitor in human tissues

2010 ◽  
Vol 79 (10) ◽  
pp. 1526-1533 ◽  
Author(s):  
Chunze Li ◽  
Bing Lu ◽  
Robert M. Garbaccio ◽  
Edward S. Tasber ◽  
Mark E. Fraley ◽  
...  
Keyword(s):  
Human Tissues ◽  
Stereospecific Reduction ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitor

Stereospecific reduction of haloperidol in human tissues

1992 ◽  
Vol 44 (5) ◽  
pp. 867-871 ◽  
Author(s):  
Darryl W. Eyles ◽  
Susan M. Pond
Keyword(s):  
Human Tissues ◽  
Stereospecific Reduction

Phase I trial of novel kinesin spindle protein (KSP) inhibitor SB-715992 IV days 1, 8, 15 q 28 days

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 2004-2004 ◽  
Author(s):  
H. A. Burris ◽  
P. Lorusso ◽  
S. Jones ◽  
T. M. Guthrie ◽  
J. B. Orr ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Trial ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitor

Phase I trial of novel kinesin spindle protein (KSP) inhibitor SB-715992 IV days 1, 8, 15 q 28 days

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 2004-2004 ◽  
Author(s):  
H. A. Burris ◽  
P. Lorusso ◽  
S. Jones ◽  
T. M. Guthrie ◽  
J. B. Orr ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Trial ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitor

Phase I trial of novel kinesin spindle protein (KSP) inhibitor SB-715992 IV Q 21 days

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 2078-2078 ◽  
Author(s):  
Q. S. Chu ◽  
K. D. Holen ◽  
E. K. Rowinsky ◽  
G. Wilding ◽  
J. L. Volkman ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Trial ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitor

A phase I-II trial of the kinesin spindle protein (KSP) inhibitor SB-743921 on days 1 and 15 every 28 days in non-Hodgkin or Hodgkin lymphoma

2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 8539-8539 ◽  
Author(s):  
O. A. O’Connor ◽  
A. Goy ◽  
R. Orlowski ◽  
J. D. Hainsworth ◽  
J. P. Leonard ◽  
...  
Keyword(s):  
Phase I ◽  
Hodgkin Lymphoma ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitor

scholarly journals A phase I trial of MK-0731, a Kinesin Spindle Protein (KSP) inhibitor, in patients with solid tumors

2011 ◽  
Vol 30 (3) ◽  
pp. 1088-1095 ◽  
Author(s):  
Kyle Holen ◽  
Robert DiPaola ◽  
Glenn Liu ◽  
Antoinette R. Tan ◽  
George Wilding ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Trial ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitor

Phase I trial of novel kinesin spindle protein (KSP) inhibitor SB-715992 IV Q 21 days

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 2078-2078 ◽  
Author(s):  
Q. S. Chu ◽  
K. D. Holen ◽  
E. K. Rowinsky ◽  
G. Wilding ◽  
J. L. Volkman ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Trial ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitor

Phase I study to determine tolerability and pharmacokinetics (PK) of SB-743921, a novel kinesin spindle protein (KSP) inhibitor

2005 ◽  
Vol 23 (16_suppl) ◽  
pp. 2010-2010 ◽  
Author(s):  
K. D. Holen ◽  
C. P. Belani ◽  
G. Wilding ◽  
S. Ramalingam ◽  
J. L. Volkman ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Study ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitor
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