Activation of ERK1/2-mTORC1-NOX4 mediates TGF-β1-induced epithelial-mesenchymal transition and fibrosis in retinal pigment epithelial cells

Soo-Jin Kim; Yun-Sang Kim; Jeong Hun Kim; Ha Young Jang; Dat Da Ly; Ranjan Das; Kyu-Sang Park

doi:10.1016/j.bbrc.2020.06.034

Activation of ERK1/2-mTORC1-NOX4 mediates TGF-β1-induced epithelial-mesenchymal transition and fibrosis in retinal pigment epithelial cells

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2020.06.034 ◽

2020 ◽

Vol 529 (3) ◽

pp. 747-752

Author(s):

Soo-Jin Kim ◽

Yun-Sang Kim ◽

Jeong Hun Kim ◽

Ha Young Jang ◽

Dat Da Ly ◽

...

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Tgf Β1 ◽

Pigment Epithelial Cells

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MicroRNA-29b regulates TGF-β1-mediated epithelial–mesenchymal transition of retinal pigment epithelial cells by targeting AKT2

Experimental Cell Research ◽

10.1016/j.yexcr.2014.09.026 ◽

2016 ◽

Vol 345 (2) ◽

pp. 115-124 ◽

Cited By ~ 21

Author(s):

Min Li ◽

Hui Li ◽

Xiaoqiang Liu ◽

Ding Xu ◽

Fang Wang

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Tgf Β1 ◽

Pigment Epithelial Cells

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Role of LINC01592 in TGF-β1-induced epithelial-mesenchymal transition of retinal pigment epithelial cells

Aging ◽

10.18632/aging.203023 ◽

2021 ◽

Author(s):

Ying Su ◽

Ziyan Tang ◽

Feng Wang

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Tgf Β1 ◽

Pigment Epithelial Cells

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Eupatilin attenuates TGF-β2-induced proliferation and epithelial-mesenchymal transition of retinal pigment epithelial cells

Cutaneous and Ocular Toxicology ◽

10.1080/15569527.2021.1902343 ◽

2021 ◽

pp. 1-24

Author(s):

Ayca Kupeli Cinar ◽

S. Altan Ozal ◽

Riza Serttas ◽

Suat Erdogan

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Download Full-text

High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells

International Journal of Molecular Medicine ◽

10.3892/ijmm.2016.2768 ◽

2016 ◽

Vol 38 (6) ◽

pp. 1815-1822 ◽

Cited By ~ 9

Author(s):

Di Che ◽

Ti Zhou ◽

Yuqing Lan ◽

Jinye Xie ◽

Haijun Gong ◽

...

Keyword(s):

Epithelial Cells ◽

High Glucose ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

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Blocking connexin43 hemichannels prevents TGF‐β2 upregulation and epithelial‐mesenchymal transition in retinal pigment epithelial cells

Cell Biology International ◽

10.1002/cbin.11718 ◽

2021 ◽

Author(s):

Heather Lyon ◽

Naibo Yin ◽

Ilva D. Rupenthal ◽

Colin R. Green ◽

Odunayo O. Mugisho

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Download Full-text

Exosomes mediate an epithelial‐mesenchymal transition cascade in retinal pigment epithelial cells: Implications for proliferative vitreoretinopathy

Journal of Cellular and Molecular Medicine ◽

10.1111/jcmm.15951 ◽

2020 ◽

Vol 24 (22) ◽

pp. 13324-13335

Author(s):

Yao Zhang ◽

Kaizhe Wang ◽

Jiabin Pan ◽

Shuai Yang ◽

Haipei Yao ◽

...

Keyword(s):

Epithelial Cells ◽

Proliferative Vitreoretinopathy ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Download Full-text

Peer Review #3 of "Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy (v0.2)"

10.7287/peerj.10136v0.2/reviews/3 ◽

2020 ◽

Keyword(s):

Epithelial Cells ◽

Peer Review ◽

Proliferative Vitreoretinopathy ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Download Full-text

MicroRNA‑29b participates in the epithelial‑mesenchymal transition of retinal pigment epithelial cells through p‑p65

Experimental and Therapeutic Medicine ◽

10.3892/etm.2021.10300 ◽

2021 ◽

Vol 22 (2) ◽

Author(s):

Min Li ◽

Hui Li ◽

Shuai Yang ◽

Xin Liao ◽

Chun Zhao ◽

...

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Download Full-text

The role of mechanical stretch and TGF-β2 in epithelial-mesenchymal transition of retinal pigment epithelial cells

International Journal of Ophthalmology ◽

10.18240/ijo.2019.12.03 ◽

2019 ◽

Vol 12 (12) ◽

pp. 1832-1838 ◽

Cited By ~ 3

Author(s):

Qian Cao

Keyword(s):

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Mechanical Stretch ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Download Full-text

Peer Review #2 of "Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy (v0.1)"

10.7287/peerj.10136v0.1/reviews/2 ◽

2020 ◽

Author(s):

S He

Keyword(s):

Epithelial Cells ◽

Peer Review ◽

Proliferative Vitreoretinopathy ◽

Retinal Pigment Epithelial ◽

Epithelial Mesenchymal Transition ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Mesenchymal Transition ◽

Pigment Epithelial ◽

Pigment Epithelial Cells

Download Full-text