Steric configuration-enabled selective antimicrobial activity of chiral cysteine

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Jing Qian ◽  
Jiayi Gu ◽  
Wenjing Yan ◽  
Jianhao Zhang
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2009 ◽  
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Atul Kumar Tiwari ◽  
Munesh Kumar Gupta ◽  
Govind Pandey ◽  
Roger J. Narayan ◽  
Prem C. Pandey

Abstract


Biopolymers ◽  
2017 ◽  
Vol 108 (3) ◽  
pp. e23006 ◽  
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Zachary B. Jenner ◽  
Christopher M. Crittenden ◽  
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Kerry A. Bruns

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2015 ◽  
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Adam A. Strömstedt ◽  
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Jan G. Bruhn ◽  
Hesham El-Seedi ◽  
...  

2009 ◽  
Vol 13 (1) ◽  
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Pan Dong Ryu

2019 ◽  
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Tathagata Mondal ◽  
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Amrita Sikder ◽  
Suhrit Ghosh

2020 ◽  
Vol 15 (1) ◽  
pp. 1934578X2090140
Author(s):  
Nicholas J. Morehouse ◽  
Andrew J. Flewelling ◽  
John A. Johnson ◽  
Christopher A. Gray

An extract of the fungus Penicillium roseopurpureum (KP1-135C) isolated from the marine alga Petalonia fascia showed selective antimicrobial activity against Staphylococcus aureus and Mycobacterium tuberculosis H37Ra. Bioassay-guided fractionation revealed that three halogenated bianthrones, neobulgarone D, neobulgarone E, and neobulgarone F, were responsible for the observed activity of the extract. The stereochemistry of the neobulgarones was unambiguously assigned based on polarimetric data and the analysis of 1H-nuclear magnetic resonance data obtained for the three bianthrones.


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